NBME practice exam #1
Questions and Answers 100%
PASS
Mitotic cyclin synthesis—ANSWER-G2 phase
Vitamin E def anemia—ANSWER-Hemolytic anemia~ red antioxidants vs B12 def
(megaloblastic macrocytic anemia)
Hemolysis~ dec Hgb/hematocrit, inc LDH (normal MCV), and neurologic symptoms
vs B12 def: dec Hgb/hematocrit, inc MCV, and neurologic symptoms (dorsal column)
Volume of distribution—ANSWER-Vd = (amount of drug in the body) / (plasma drug
concentration)
Achondroplasia—ANSWER-Endochondrial ossification dysfunction (inhibit chondrocyte
proliferation)
TGF beta over expression—ANSWER-Fibroblast growth factor ~ keloid and hypertrophic scar
development
,Thyroglossal duct cyst—ANSWER-a palpable cystic midline mass (fill w/mucous) in the neck
sub>supra hyoid bone ~incomplete closure of the thyroglossal duct lined by lymphoid and
mucous cells
Connects tongue to thyroid gland developing: originates from tongue tissue
Doesn't close completely-> cyst (fill w/mucous)
-enlarge in infections, inc mucous, form thyroid cancer via ectopic thyroid tissue
Moves w/tongue mvmt
Immunoreactive trypsinogen (IRT)—ANSWER-Measurement in blood of newborn babies is
an assay in rapidly increasing use as a screening test for cystic fibrosis
Positive~ CF (2 mutations- AR to cause CF phenotype)
Mullerian agenesis (Mayer-Rokitansky-Kuster-Hauser syndrome) vs androgen insensitivity—
ANSWER-Both present w/blind vaginal pouch and absent 1st menstrual period
© 2026 Copyright. All Rights Reserved. This document is
protected by copyright law, Copyrighted By Brittie Donald
, AI: XY w/absent hair development (inc tesoterone-> estrogen production and female
characteristics) MIF still made in embryo, also may be very tall~ lack of androgen mediated
growth plate closure
MA: XX w/NORMAL hair development
suspensory ligament of ovary—ANSWER-Ligament that contains ovarian vessels
-posterior to ligament~ ureter
Oophorectomy: divides suspensory ligament~ risk of ovarian vessel of ureter damage
Ureter: also runs behind the uterine artery (F) and vas deferens (M) near its entrance to the
bladder
delirium tremens (DTs)—ANSWER-the dramatic physical and psychological effects of alcohol
withdrawal
-> autonomic instability~ hypokalemia (catecholamine mediated intracellular shifts of K+ via
inc Na/K+ ATPase activity)-> arrythmias
Beneficence—ANSWER-weighing risks and costs of procedure against the benefits of treat
ment vs nonmaleficence: avoiding the causation of harm
Questions and Answers 100%
PASS
Mitotic cyclin synthesis—ANSWER-G2 phase
Vitamin E def anemia—ANSWER-Hemolytic anemia~ red antioxidants vs B12 def
(megaloblastic macrocytic anemia)
Hemolysis~ dec Hgb/hematocrit, inc LDH (normal MCV), and neurologic symptoms
vs B12 def: dec Hgb/hematocrit, inc MCV, and neurologic symptoms (dorsal column)
Volume of distribution—ANSWER-Vd = (amount of drug in the body) / (plasma drug
concentration)
Achondroplasia—ANSWER-Endochondrial ossification dysfunction (inhibit chondrocyte
proliferation)
TGF beta over expression—ANSWER-Fibroblast growth factor ~ keloid and hypertrophic scar
development
,Thyroglossal duct cyst—ANSWER-a palpable cystic midline mass (fill w/mucous) in the neck
sub>supra hyoid bone ~incomplete closure of the thyroglossal duct lined by lymphoid and
mucous cells
Connects tongue to thyroid gland developing: originates from tongue tissue
Doesn't close completely-> cyst (fill w/mucous)
-enlarge in infections, inc mucous, form thyroid cancer via ectopic thyroid tissue
Moves w/tongue mvmt
Immunoreactive trypsinogen (IRT)—ANSWER-Measurement in blood of newborn babies is
an assay in rapidly increasing use as a screening test for cystic fibrosis
Positive~ CF (2 mutations- AR to cause CF phenotype)
Mullerian agenesis (Mayer-Rokitansky-Kuster-Hauser syndrome) vs androgen insensitivity—
ANSWER-Both present w/blind vaginal pouch and absent 1st menstrual period
© 2026 Copyright. All Rights Reserved. This document is
protected by copyright law, Copyrighted By Brittie Donald
, AI: XY w/absent hair development (inc tesoterone-> estrogen production and female
characteristics) MIF still made in embryo, also may be very tall~ lack of androgen mediated
growth plate closure
MA: XX w/NORMAL hair development
suspensory ligament of ovary—ANSWER-Ligament that contains ovarian vessels
-posterior to ligament~ ureter
Oophorectomy: divides suspensory ligament~ risk of ovarian vessel of ureter damage
Ureter: also runs behind the uterine artery (F) and vas deferens (M) near its entrance to the
bladder
delirium tremens (DTs)—ANSWER-the dramatic physical and psychological effects of alcohol
withdrawal
-> autonomic instability~ hypokalemia (catecholamine mediated intracellular shifts of K+ via
inc Na/K+ ATPase activity)-> arrythmias
Beneficence—ANSWER-weighing risks and costs of procedure against the benefits of treat
ment vs nonmaleficence: avoiding the causation of harm
