answers 2025\2025 A+ Grade
Antibiotic Classes and examples of infectious disease drugs
- correct answer ß-Lactams : penicillins
-Penicillin G, V
-Nafcillin, oxacillin, dicloxacillin
-ampicillin, amoxicillin
-piperacillin
-combo-amp/sulbactam(unasyn), amox/clav (augmentin), pip/taco (zosyn)
B-lactation: cephalosporin
-cephalexin (keflex)
-cefoxitin (mefoxin)
-cefotaxime (claforan)
-cefepime (maxipime)
-ceftaroline (teflaro)
Fluoroquinolones
-ciprofloxacin (cipro)
-ofloxacin (floxin)
-levofloxacin (levaquin)
-moxifloxacin (avelox)
Tetracyclines and Macrolides
-tetracycline, doxycycline
-erythromycin, azithromycin(zithromax), clarithromycin (Biaxin)
Sulfonamides, Trimethoprim, and Nitrofurantoin
-sulfadiazine, sulfamethoxazole(bactrim)
-trimethoprim (primsol)
-TMP/SMZ: trimethoprim/sulfamethoxazole
,-nitrofurantoin (macrodantin)
Examples of cell wall synthesis inhibitors
- correct answer penicillin, cephalosporin, imipenem, vancomycin
What are the considerations when choosing antibiotic therapy
- correct answer *The HOST
-history of allergy, cross allergy or intolerance
-preexisting conditions: HIV, cancer, autoimmune disorders, diabetes
-renal/hepatic function-cr clearance
-Age, pregnancy and lactation, recent antibiotic use, exposure history (wt based dosing for pediatric and
geriatric population)
*The SYNDROME or PRESENTING ILLNESS
-what system is impacted
-how aggressive the infection
-consider non-bacterial causes
-carefully examine clinical presentation of illness
*The PATHOGEN
-obtaining culture and sensitivity/resistance
-how susceptibility is determined
AST/Petri dish growth
When prescribing macrolides what is the patient teaching
- correct answer Take with food to reduce G.I. disturbances
Which antibiotic should have a culture done before therapy begins
- correct answer Vancomyosin, Carbapenem, Penicillin
Which antibiotics do not require a culture prior to start of therapy
- correct answer Tetracyclines and macrolides
, Situations when PO or IV antibiotics should be prescribed
- correct answer critical or severe infections Iv
Mild/moderate or a patients admitted for other diagnoses who have an infection PO
When can IV antibiotics be switched to PO?
- correct answer WHen pt is stable
Bactericides antibiotics
- correct answer Directly kill bacteria
Examples include aminoglycosides Beta lactums, Fluoroquinolones, metronidazole, most
antimycobacterial agents, streptogramins, and vancomycin
Bacteriostatic agents
- correct answer Inhibit bacterial proliferation while the hosts immune system does the killing
Examples include Clindamycin, macrolides sulfonamides and tetracyclines
Broad-spectrum antibiotic uses
- correct answer Target wider number of bacteria types
Acts on both Graham negative and gram-positive organisms
Commonly used for empiric therapy when the pathogen is unknown or infection with multiple types of
bacteria and suspected
commonly used for empiric therapy when the pathogen is unknown or infection with multiple types of
bacteria and suspected
Risks of using broad-spectrum antibiotics
- correct answer Disruption of normal flora and development of anabiotic resistance
Narrow spectrum antibiotic uses
- correct answer Affective against a specific bacteria type used when infecting pathogens are known
reduces risk of disruption of normal flora and
reduce development of anabiotic resistance