TEST BANK j
PharmacotherapeuticsjforjAdvancedjPractice:jAjPracticaljApproach
byjVirginiajPoolejArcangelo,jAndrewjM.jPeterson
FifthjEdition
FULL TEST BANK!!!
j j
,Chapterj1jIssuesjforjthejPractitionerjinjDrugjTherapy
MULTIPLEjCHOICE
1. Nursejpractitionerjprescriptivejauthorityjisjregulatedjby:
A. ThejNationaljCounciljofjStatejBoardsjofjNursing
B. ThejU.S.jDrugjEnforcementjAdministration
C. ThejStatejBoardjofjNursingjforjeachjstate
D. ThejStatejBoardjofjPharmacy
ANS:j C PTS:j 1
2. PhysicianjAssistantj(PA)jprescriptivejauthorityjisjregulatedjby:
A. ThejNationaljCounciljofjStatejBoardsjofjNursing
B. ThejU.S.jDrugjEnforcementjAdministration
C. ThejStatejBoardjofjNursing
D. ThejStatejBoardjofjMedicaljExaminers
ANS:j D PTS:j 1
3. Clinicaljjudgmentjinjprescribingjincludes:
A. Factoringjinjthejcostjtojthejpatientjofjthejmedicationjprescribed
B. Alwaysjprescribingjthejnewestjmedicationjavailablejforjthejdiseasejprocess
C. Handingjoutjdrugjsamplesjtojpoorjpatients
D. Prescribingjalljgenericjmedicationsjtojcutjcosts
ANS:j A PTS:j 1
4. Criteriajforjchoosingjanjeffectivejdrugjforjajdisorderjinclude:
A. Askingjthejpatientjwhatjdrugjtheyjthinkjwouldjworkjbestjforjthem
B. Consultingjnationallyjrecognizedjguidelinesjforjdiseasejmanagement
C. Prescribingjmedicationsjthatjarejavailablejasjsamplesjbeforejwritingjajprescription
D. FollowingjU.S.jDrugjEnforcementjAdministrationj(DEA)jguidelinesjforjp
rescribing
ANS:j B PTS:j 1
5. Nursejpractitionerjpracticejmayjthrivejunderjhealth-carejreformjduejto:
A. Thejdemonstratedjabilityjofjnursejpractitionersjtojcontroljcostsjandjimprovejpatientjo
utcomes
B. Thejfactjthatjnursejpractitionersjwilljbejablejtojpracticejindependently
C. Thejfactjthatjnursejpractitionersjwilljhavejfulljreimbursementjunderjhealth-
carejreform
D. ThejabilityjtojshiftjaccountabilityjforjMedicaidjtojthejstatejlevel
ANS:j A PTS:j 1
, 14
jj
lOMoAR cPSD| 210076
Chapterj2.PharmacokineticjBasisjofjTherapeuticsjandjPharmacodynamic
MULTIPLEjCHOICE
1. Ajpatient'sjnutritionaljintakejandjlabjworkjreflectsjhypoalbuminemia.jThisjisjcriticaljtojpr
escribingjbecause:
A. Distributionjofjdrugsjtojtargetjtissuejmayjbejaffected
B. Thejsolubilityjofjthejdrugjwilljnotjmatchjthejsitejofjabsorption
C. Therejwilljbejlessjfreejdrugjavailablejtojgeneratejanjeffect
D. Drugsjboundjtojalbuminjarejreadilyjexcretedjbyjthejkidney
ANS:j A PTS:j 1
2. Drugsjthatjhavejajsignificantjfirst-passjeffect:
A. Mustjbejgivenjbyjthejenteralj(oral)jroutejonly
B. Bypassjthejhepaticjcirculation
C. Arejrapidlyjmetabolizedjbyjthejliverjandjmayjhavejlittlejifjanyjdesiredjaction
D. Arejconvertedjbyjthejliverjtojmorejactivejandjfat-solublejforms
ANS:j C PTS:j 1
3. Thejroutejofjexcretionjofjajvolatilejdrugjwilljlikelyjbe:
A. Thejkidneys
B. Thejlungs
C. Thejbilejandjfeces
D. Thejskin
ANS:j B PTS:j 1
4. Medroxyprogesteronej(DepojProvera)jisjprescribedjIMjtojcreatejajstoragejreservoirjofjthejdr
ug.jStoragejreservoirs:
A. Assurejthatjthejdrugjwilljreachjitsjintendedjtargetjtissue
B. Arejthejreasonjforjgivingjloadingjdoses
C. Increasejthejlengthjofjtimejajdrugjisjavailablejandjactive
D. Arejmostjcommonjinjcollagenjtissues
ANS:j C PTS:j 1
5. ThejNPjchoosesjtojgivejcephalexinjeveryj8jhoursjbasedjonjknowledgejofjthejdrug's:
A. Propensityjtojgojtojthejtargetjreceptor
B. Biologicaljhalf-life
C. Pharmacodynamics
D. Safetyjandjsidejeffects
ANS:j B PTS:j 1
6. Azithromycinjdosingjrequiresjthejfirstjday'sjdosejbejtwicejthosejofjthejotherj4jdaysjofjthejpre
scription.jThisjisjconsideredjajloadingjdose.jAjloadingjdose:
A. Rapidlyjachievesjdrugjlevelsjinjthejtherapeuticjrange
B. Requiresjfourjtojfivejhalf-livesjtojattain
C. Isjinfluencedjbyjrenaljfunction
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jj
lOMoAR cPSD| 210076
D. Isjdirectlyjrelatedjtojthejdrugjcirculatingjtojthejtargetjtissues
ANS:j A PTS:j j 1
7. Thejpointjinjtimejonjthejdrugjconcentrationjcurvejthatjindicatesjthejfirstjsignjofjajtherapeuticjeff
ectjisjthe:
A. Minimumjadversejeffectjlevel
B. Peakjofjaction
C. Onsetjofjaction
D. Therapeuticjrange
ANS:j C PTS:j 1
8. Phenytoinjrequiresjajtroughjleveljbejdrawn.jPeakjandjtroughjlevelsjarejdone:
A. Whenjthejdrugjhasjajwidejtherapeuticjrange
B. Whenjthejdrugjwilljbejadministeredjforjajshortjtimejonly
C. Whenjtherejisjajhighjcorrelationjbetweenjthejdosejandjsaturationjofjreceptorjsites
D. Tojdeterminejifjajdrugjisjinjthejtherapeuticjrange
ANS:j D PTS:j 1
9. Ajlaboratoryjresultjindicatesjthejpeakjleveljforjajdrugjisjabovejthejminimumjtoxicjco
ncentration.jThisjmeansjthatjthe:
A. Concentrationjwilljproducejtherapeuticjeffects
B. Concentrationjwilljproducejanjadversejresponse
C. Timejbetweenjdosesjmustjbejshortened
D. Durationjofjactionjofjthejdrugjisjtoojlong
ANS:j B PTS:j 1
10. Drugsjthatjarejreceptorjagonistsjmayjdemonstratejwhatjproperty?
A. Irreversiblejbindingjtojthejdrugjreceptorjsite
B. Up-regulationjwithjchronicjuse
C. Desensitizationjorjdown-regulationjwithjcontinuousjuse
D. Inversejrelationshipjbetweenjdrugjconcentrationjandjdrugjaction
ANS:j C PTS:j 1
11. Drugsjthatjarejreceptorjantagonists,jsuchjasjbetajblockers,jmayjcause:
A. Down-regulationjofjthejdrugjreceptor
B. Anjexaggeratedjresponsejifjabruptlyjdiscontinued
C. Partialjblockadejofjthejeffectsjofjagonistjdrugs
D. Anjexaggeratedjresponsejtojcompetitivejdrugjagonists
ANS:j B PTS:j 1
12. Factorsjthatjaffectjgastricjdrugjabsorptionjinclude:
A. Liverjenzymejactivity
B. Protein-bindingjpropertiesjofjthejdrugjmolecule
C. Lipidjsolubilityjofjthejdrug
D. Abilityjtojchewjandjswallow
ANS:j C PTS:j 1
WWW.TEGTBANKTANK.COM
PharmacotherapeuticsjforjAdvancedjPractice:jAjPracticaljApproach
byjVirginiajPoolejArcangelo,jAndrewjM.jPeterson
FifthjEdition
FULL TEST BANK!!!
j j
,Chapterj1jIssuesjforjthejPractitionerjinjDrugjTherapy
MULTIPLEjCHOICE
1. Nursejpractitionerjprescriptivejauthorityjisjregulatedjby:
A. ThejNationaljCounciljofjStatejBoardsjofjNursing
B. ThejU.S.jDrugjEnforcementjAdministration
C. ThejStatejBoardjofjNursingjforjeachjstate
D. ThejStatejBoardjofjPharmacy
ANS:j C PTS:j 1
2. PhysicianjAssistantj(PA)jprescriptivejauthorityjisjregulatedjby:
A. ThejNationaljCounciljofjStatejBoardsjofjNursing
B. ThejU.S.jDrugjEnforcementjAdministration
C. ThejStatejBoardjofjNursing
D. ThejStatejBoardjofjMedicaljExaminers
ANS:j D PTS:j 1
3. Clinicaljjudgmentjinjprescribingjincludes:
A. Factoringjinjthejcostjtojthejpatientjofjthejmedicationjprescribed
B. Alwaysjprescribingjthejnewestjmedicationjavailablejforjthejdiseasejprocess
C. Handingjoutjdrugjsamplesjtojpoorjpatients
D. Prescribingjalljgenericjmedicationsjtojcutjcosts
ANS:j A PTS:j 1
4. Criteriajforjchoosingjanjeffectivejdrugjforjajdisorderjinclude:
A. Askingjthejpatientjwhatjdrugjtheyjthinkjwouldjworkjbestjforjthem
B. Consultingjnationallyjrecognizedjguidelinesjforjdiseasejmanagement
C. Prescribingjmedicationsjthatjarejavailablejasjsamplesjbeforejwritingjajprescription
D. FollowingjU.S.jDrugjEnforcementjAdministrationj(DEA)jguidelinesjforjp
rescribing
ANS:j B PTS:j 1
5. Nursejpractitionerjpracticejmayjthrivejunderjhealth-carejreformjduejto:
A. Thejdemonstratedjabilityjofjnursejpractitionersjtojcontroljcostsjandjimprovejpatientjo
utcomes
B. Thejfactjthatjnursejpractitionersjwilljbejablejtojpracticejindependently
C. Thejfactjthatjnursejpractitionersjwilljhavejfulljreimbursementjunderjhealth-
carejreform
D. ThejabilityjtojshiftjaccountabilityjforjMedicaidjtojthejstatejlevel
ANS:j A PTS:j 1
, 14
jj
lOMoAR cPSD| 210076
Chapterj2.PharmacokineticjBasisjofjTherapeuticsjandjPharmacodynamic
MULTIPLEjCHOICE
1. Ajpatient'sjnutritionaljintakejandjlabjworkjreflectsjhypoalbuminemia.jThisjisjcriticaljtojpr
escribingjbecause:
A. Distributionjofjdrugsjtojtargetjtissuejmayjbejaffected
B. Thejsolubilityjofjthejdrugjwilljnotjmatchjthejsitejofjabsorption
C. Therejwilljbejlessjfreejdrugjavailablejtojgeneratejanjeffect
D. Drugsjboundjtojalbuminjarejreadilyjexcretedjbyjthejkidney
ANS:j A PTS:j 1
2. Drugsjthatjhavejajsignificantjfirst-passjeffect:
A. Mustjbejgivenjbyjthejenteralj(oral)jroutejonly
B. Bypassjthejhepaticjcirculation
C. Arejrapidlyjmetabolizedjbyjthejliverjandjmayjhavejlittlejifjanyjdesiredjaction
D. Arejconvertedjbyjthejliverjtojmorejactivejandjfat-solublejforms
ANS:j C PTS:j 1
3. Thejroutejofjexcretionjofjajvolatilejdrugjwilljlikelyjbe:
A. Thejkidneys
B. Thejlungs
C. Thejbilejandjfeces
D. Thejskin
ANS:j B PTS:j 1
4. Medroxyprogesteronej(DepojProvera)jisjprescribedjIMjtojcreatejajstoragejreservoirjofjthejdr
ug.jStoragejreservoirs:
A. Assurejthatjthejdrugjwilljreachjitsjintendedjtargetjtissue
B. Arejthejreasonjforjgivingjloadingjdoses
C. Increasejthejlengthjofjtimejajdrugjisjavailablejandjactive
D. Arejmostjcommonjinjcollagenjtissues
ANS:j C PTS:j 1
5. ThejNPjchoosesjtojgivejcephalexinjeveryj8jhoursjbasedjonjknowledgejofjthejdrug's:
A. Propensityjtojgojtojthejtargetjreceptor
B. Biologicaljhalf-life
C. Pharmacodynamics
D. Safetyjandjsidejeffects
ANS:j B PTS:j 1
6. Azithromycinjdosingjrequiresjthejfirstjday'sjdosejbejtwicejthosejofjthejotherj4jdaysjofjthejpre
scription.jThisjisjconsideredjajloadingjdose.jAjloadingjdose:
A. Rapidlyjachievesjdrugjlevelsjinjthejtherapeuticjrange
B. Requiresjfourjtojfivejhalf-livesjtojattain
C. Isjinfluencedjbyjrenaljfunction
, 14
jj
lOMoAR cPSD| 210076
D. Isjdirectlyjrelatedjtojthejdrugjcirculatingjtojthejtargetjtissues
ANS:j A PTS:j j 1
7. Thejpointjinjtimejonjthejdrugjconcentrationjcurvejthatjindicatesjthejfirstjsignjofjajtherapeuticjeff
ectjisjthe:
A. Minimumjadversejeffectjlevel
B. Peakjofjaction
C. Onsetjofjaction
D. Therapeuticjrange
ANS:j C PTS:j 1
8. Phenytoinjrequiresjajtroughjleveljbejdrawn.jPeakjandjtroughjlevelsjarejdone:
A. Whenjthejdrugjhasjajwidejtherapeuticjrange
B. Whenjthejdrugjwilljbejadministeredjforjajshortjtimejonly
C. Whenjtherejisjajhighjcorrelationjbetweenjthejdosejandjsaturationjofjreceptorjsites
D. Tojdeterminejifjajdrugjisjinjthejtherapeuticjrange
ANS:j D PTS:j 1
9. Ajlaboratoryjresultjindicatesjthejpeakjleveljforjajdrugjisjabovejthejminimumjtoxicjco
ncentration.jThisjmeansjthatjthe:
A. Concentrationjwilljproducejtherapeuticjeffects
B. Concentrationjwilljproducejanjadversejresponse
C. Timejbetweenjdosesjmustjbejshortened
D. Durationjofjactionjofjthejdrugjisjtoojlong
ANS:j B PTS:j 1
10. Drugsjthatjarejreceptorjagonistsjmayjdemonstratejwhatjproperty?
A. Irreversiblejbindingjtojthejdrugjreceptorjsite
B. Up-regulationjwithjchronicjuse
C. Desensitizationjorjdown-regulationjwithjcontinuousjuse
D. Inversejrelationshipjbetweenjdrugjconcentrationjandjdrugjaction
ANS:j C PTS:j 1
11. Drugsjthatjarejreceptorjantagonists,jsuchjasjbetajblockers,jmayjcause:
A. Down-regulationjofjthejdrugjreceptor
B. Anjexaggeratedjresponsejifjabruptlyjdiscontinued
C. Partialjblockadejofjthejeffectsjofjagonistjdrugs
D. Anjexaggeratedjresponsejtojcompetitivejdrugjagonists
ANS:j B PTS:j 1
12. Factorsjthatjaffectjgastricjdrugjabsorptionjinclude:
A. Liverjenzymejactivity
B. Protein-bindingjpropertiesjofjthejdrugjmolecule
C. Lipidjsolubilityjofjthejdrug
D. Abilityjtojchewjandjswallow
ANS:j C PTS:j 1
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