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FORPATHOPHYSIOLOGY2NDEDITION
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BY CAPRIOTTI
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, Chapter 1, The Cell in Health and Illness
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Multiple Choice
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Identify the choice that best completes the statement or answers the question.
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1. Which statement regarding the sodium–potassium pump is correct?
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1. The cell’s plasma membrane is more soluble to sodium ions than potassium ions.
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2. The concentration of sodium ions should be higher inside the cell compartment.
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3. The concentration of potassium ions should be higher outside the cell
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compartment.
4. The active transport involves pumping out three sodium ions and pumping in two
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potassium ions. q
2. In the absence of oxygen, which cellular function creates the same amount of energy as is created in
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the presence of oxygen?
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1. Dissipation of pyruvic acid q q q
2. Initiation of the citric acid cycle q q q q q
3. Activation of acetyl-coenzyme A q q q
4. Creation of acidosis via lactic acid q q q q q
3. How many adenosine triphosphates (ATPs) are produced in aerobic energy metabolism?
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1. 2 q q
2. 3 q q
3. 34 q q
4. 53 q q
4. Which cell organelles differ in their number according to the cell’s energy needs?
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1. Ribosomes
2. Mitochondria
3. Ribonucleic acids q
4. Deoxyribonucleic acids q
5. Which option best supports the reason more energy is produced when a person is exercising?
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1. Exercise causes an increase in the synthesis of protein. q q q q q q q q
2. There is an increase in the production of pyruvic acid in the cells.
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3. The conversion of pyruvic acid to lactic acid is increased by exercise.
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4. Muscle cells have more mitochondria to meet energy demands.
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6. When does ribosomal protein synthesis cease?
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1. During endoplasmic reticulum stress q q q
2. During the synthesis of adenosine triphosphate (ATP)
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3. During a severe hypoxic state q q q q
4. During the processing of prohormone q q q q
7. Which cellular organelles are responsible for propelling mucus and inhaled debris out of the lungs?
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1. Cilia
2. Microfilaments
3. Secretory vesicles q
, 4. Endoplasmic reticula q
q 8. Which are the key proteins in the contractile units of the muscle cells?
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1. Actin and myosin q q
2. Prohormone and tubulin q q
3. Tubulin and actin q q
4. Myosin and prohormone q q
q 9. q Which deficiency causes Tay–Sachs disease?
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1. Proteasome
2. Peroxisome
3. Macrophage
4. Lysosomal enzymes q
10. Which is a characteristic of adrenoleukodystrophy?
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1. Accumulation of ganglioside q q
2. Cessation of ribosomal protein synthesis q q q q
3. Acceleration of cellular proteasome activity q q q q
4. Accumulation of long-chain fatty acids in the nervous system q q q q q q q q
11. Which statement regarding endoplasmic reticulum (ER) stress is correct?
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1. During ER stress, proteins are rapidly degraded.
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2. During ER stress, lipids cannot travel to their proper intracellular locations.
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3. During ER stress, long-chain fatty acids accumulate in the nervous system.
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4. During ER stress, n o n d eNgU
r aRd eSdI sT
qtaB
nc.eC
s Oa c cumulate in the cesll.
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12. A client is diagnosed with type 1 diabetes mellitus. At a cellular level, which function is likely to be
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involved?
1. Inability of ribosomes to produce a specific type of protein
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2. Incorrect processing of a protein by the Golgi apparatus q q q q q q q q
3. Stagnation of a previously dynamic action in microtubules q q q q q q q
4. Obstruction of the smooth endoplasmic reticulum q q q q q
13. A newborn patient exhibits characteristics of severe physical deformities. Which cellular component
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is examined to determine the cause and probability of the disease being genetically transferred?
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1. Transfer RNA q
2. Ribosomal RNA q
3. Double helix of DNA q q q
4. Mitochondrial DNA q
14. A hiker experiences muscle pain and acidosis while ascending a mountain during a long, steep
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climb. Which is the reason for these manifestations?
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1. Cellular hypoxia q
2. Autolysis
3. Heterolysis
4. Cellular edema q
15. Which factor provides DNA the unique molecular ability to replicate?
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1. The pairing of nitrogenous bases
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, 2. The presence of pyrimidine bases
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3. The presence of nucleotides
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4. The nitrogenous base and phosphate bond
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16. How many nitrogenous bases compose a single codon?
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1. 2 q q
2. 3 q q
3. 4 q q
4. 5 q q
17. Which components form the structure of DNA?
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1. Nucleotides
2. Amino acids q
3. Fatty acids q
4. Phosphates
18. Which factor is essential in order for protein synthesis to occur?
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1. Free-standing ribosomes within the cell q q q q
2. Protein blueprint from the cell of the DNA q q q q q q q
3. Specific information from the nucleus of the cell q q q q q q q
4. Transfer RNA to move the protein out of the cell q q q q q q q q q
19. Tetracycline antibiotic is prescribed for an adult client with chlamydia infection. Which is the
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mechanism of action of the drug? q q q q q
1. It prevents the replicatio
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2. It alters the configuration of bacterial cytoplasm.
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3. It interferes with the function of bacterial ribosomes.
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4. It inhibits the functions of bacterial mitochondria.
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20. Where does the conversion of a prohormone into a hormone take place?
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1. In the ribosomes q q
2. In the Golgi apparatusq q q
3. In the secretory granules
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4. In the endoplasmic reticulum
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21. Which is the cell’s “master mind”?
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1. Nucleus
2. Ribosome
3. Golgi apparatus q
4. Endoplasmic reticulum q
Multiple Response
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Identify one or more choices that best complete the statement or answer the question.
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22. Which statements regarding the microtubules are true? Select all that apply.
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1. Microtubules are solid. q q
2. Microtubules are flexible. q q
3. Microtubules are composed of tubulin. q q q q