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MedSurg 242 Unit 4 with 100+ Q&A – Fluid, Electrolyte & Acid-Base Balance (NSG242) – Hyponatremia, ABGs, Potassium, Compensation

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This document contains over 100 detailed Q&A items aligned with Unit 4 of MedSurg 242, covering high-yield topics in fluid and electrolyte balance, acid-base regulation, and critical pathophysiology. Designed for students in NSG242 or Adult Health II, it is ideal for exam prep and concept mastery in nursing programs. Each concept is clearly explained using clinical language, covering mechanisms, lab values, interventions, and causes of imbalances. Topics include: Electrolyte levels: Sodium, Potassium, Calcium, Magnesium Fluid regulation: Osmosis, Diffusion, Filtration, Hormonal control Acid-base balance: Metabolic and Respiratory Acidosis/Alkalosis Interpretation and application of ABG values, compensatory mechanisms, and nursing interventions Nursing priorities in dehydration, edema, renal function, and safety monitoring Clinical references such as Chvostek’s and Trousseau’s signs, effects of medications (e.g., diuretics, ACE inhibitors), and conditions like DKA, COPD, and renal failure are included to support diagnostic thinking. This material follows the structure and learning objectives found in the textbook “Medical-Surgical Nursing: Concepts for Interprofessional Collaborative Care” by Ignatavicius (Iggy). Perfect for students in ASN, BSN, LPN-to-RN bridge programs, or preparing for HESI, ATI, or NCLEX-RN exams. Highly useful for both lecture review and clinical application. Keywords: fluid balance, electrolyte disorders, hyponatremia, hypernatremia, hypokalemia, hyperkalemia, hypocalcemia, ABG interpretation, metabolic acidosis, respiratory alkalosis, acid-base balance, dehydration, renal perfusion, sodium levels, potassium replacement, Trousseau sign, Chvostek sign, DKA, NSG242, MedSurg Unit 4, Iggy textbook, nursing Q&A, NCLEX prep

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Medsurg 242 Unit 4
Galen/Kronenthal 2026 Expert
Verified | Ace the Test



What is filtration? - 🧠 ANSWER ✔✔The movement of fluid through a cell or

blood vessel caused by hydrostatic pressure differences on both sides of

the membrane.


What is hydrostatic pressure? - 🧠 ANSWER ✔✔Force that pushes water

outward from confined space through membrane

What determines the pressure in any body fluid space? - 🧠 ANSWER

✔✔Amount of water

,Edema - 🧠 ANSWER ✔✔Develops with changes in normal hydrostatic

pressure differences


Diffusion - 🧠 ANSWER ✔✔Free movement of particles (solute) across

permeable membrane from higher to lower concentration

Important for most electrolytes

Sodium pumps


Osmosis and filtration - 🧠 ANSWER ✔✔Act together at capillary membrane

to maintain normal ECF and ICF volumes

Ex. thirst mechanism


Hormonal regulation of fluid balance - 🧠 ANSWER ✔✔Aldosterone


Antidiuretic hormone

Natriuretic peptides


Renin-angiotensin II pathway - 🧠 ANSWER ✔✔Blood (plasma) volume and

intracellular fluid most important to keep in balance

Kidneys are major regulator of water and sodium balance; maintain blood

and perfusion pressure to all tissues/organs

When the kidneys sense a low parameter, they secrete renin

, Renin-angiotensin II pathway is greatly stimulated with shock, or when

stress response is stimulated


ACE Inhibitors - 🧠 ANSWER ✔✔Disrupt renin-angiotensin II pathway by

reducing amount of ACE produced

> angiotensin II = less vasoconstriction and reduced peripheral resistance,

lowers B/P

Greater excretion of water and sodium in urine

Pt with HTN often take


Dehydration - 🧠 ANSWER ✔✔fluid intake of the body is not sufficient to

meet the fluid needs of the body = fluid volume deficit


Dehydration assessment - 🧠 ANSWER ✔✔Physical assessment


Pt safety

Pulmonary congestion or edema, flash pulmonary edema can occur fast

Drug therapy

Nutrition therapy - monitor sodium

Monitor I&O




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