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PANCE Blueprint: Neurology (Smarty PANCE) 2026 PDF | PA Exam Study Guide

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This PANCE Blueprint: Neurology (Smarty PANCE) 2026 PDF is a focused study resource for Physician Assistant candidates preparing for the PANCE exam. It covers high-yield neurology topics including stroke, seizure disorders, headaches, neuropathies, and neurodegenerative diseases. With concise review notes, practice questions, and key clinical pearls, this guide helps learners reinforce critical neurology concepts, test their knowledge, and confidently approach neurology questions on the PANCE in 2026.

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NeurologyPANCEExamQuestionsWithcorrectanswers f f f f f f




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A 73 year-old male presents to the clinic with his wife.His wife has noticed that he has
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developed a resting tremor in his right hand and a shuffling gait over the last year.
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What finding on physical examination would support your suspected diagnosis?
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A Chorea
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B Dystonia
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C Masked facies
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D Hyperreflexia:C
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ThepatientsymptomsareconsistentwithParkinsonism.Physicalexamfindingsin- clude
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maskedfacies,micrographia,decreasedarmswing,andmonotonousspeech.
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1. A patient with an upper motor neuron lesion would exhibit which of the
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following findings?
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A Fasciculations
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B Areflexia
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C Muscular atrophy
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D Spasticity:D
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Spasticityisan uppermotor neuron lesion finding.Fasciculations,areflexia and muscle
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atrophy are consistent with lower motor neuron lesions.
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2. What test is the single most useful test in establishing the diagnosis of
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multiple sclerosis?
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, A Cerebral spinal fluid cell count and protein level
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B Cerebral spinal fluid immunoglobulin studies
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C Evoked potentials
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D Magnetic Resonance Imaging:D
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The presence of plaques on MRI is a key finding in establishing the diagnosis of MS.While
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cerebralspinalfluidcellcount,proteinlevels,andimmunoglobinsmaybe abnormal they
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are not specific for multiple sclerosis.
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Evoked potentialsaremost usefulin the detection of subclinical involvement of
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neuropathways in MS, but does not establish the diagnosis.
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3. A22-year-oldmalepresentstothecliniccomplainingofexcessivedaytime
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somnolence and strong desires to sleep at inappropriate times. He came in today
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because he had an episode of "feeling paralyzed" as he was falling asleep
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yesterday.Whatisthemostappropriatediagnostictesttoconfirmthis patient's
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diagnosis?
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A MRI of the brain
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B Electroencephalogram
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Welcome to smart study hub-your go-to-place for clear, well organized, and exam ready study notes. I provide concise summaries, solved past papers ,and detailed guides to help you learn faster and score higher . Whether you are preparing for assignments , tests , or final exams, these resources are designed to save you time and also boost your grades

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