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NR293: Antilipemic and Anemia Drugs
(Chapter 27 and 54) Questions and Answers
Latest Update
What are the functions of HMG-COA reductase inhibitors? Ans: "-statin"
Examples: Pravastatin (Pravachol), simvastatin (Zocor), atorvastatin (Lipitor)
Reduce cholesterol synthesis in liver.
Reduce inflammation, platelet aggregation and clot formation.
How would you administer HMG-COA reductase inhibitors? Ans: PO; take in
PM
What are the adverse effects of HMG-COA reductase inhibitors? Ans:
Elevations in liver enzymes or liver disease.
Mild and transient GI disturbances
Myopathy (muscle pain) possibly leading to increased serious
rhabdomyolysis.
What are the functions of bile acid sequestrants? Ans: Example:
Cholestyramine (Questran)
Bind and remove bile acid in small intestine; promotes excretion, decreases
LDL.
Adjunct to statins
© 2025 All rights reserved
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How would you administer bile acid sequestrants? Ans: PO; powdered form
Take with food and water; choking hazard when dry
Other med: Take 1 hour before or 4-6 hours after meals
What are the adverse effects of bile acid sequestrants? Ans: Nausea
Bloating
Constipation
Flatulence
What are the functions of niacin (nicotinic acid)? Ans: Reduce metabolism or
catabolism of cholesterol and triglycerides.
How would you administer niacin (nicotinic acid)? Ans: PO: Start low and
increase slowly
Take small dose of NSAID to decrease flushing
Take with meals
Other medications should be taken 1 hour before or 4 to 6 hours after meals
to avoid interference with absorption.
What are the adverse effects of niacin (nicotinic acid)? Ans: Flushing
Pruritis
GI distress
Hepatotoxic
© 2025 All rights reserved
NR293: Antilipemic and Anemia Drugs
(Chapter 27 and 54) Questions and Answers
Latest Update
What are the functions of HMG-COA reductase inhibitors? Ans: "-statin"
Examples: Pravastatin (Pravachol), simvastatin (Zocor), atorvastatin (Lipitor)
Reduce cholesterol synthesis in liver.
Reduce inflammation, platelet aggregation and clot formation.
How would you administer HMG-COA reductase inhibitors? Ans: PO; take in
PM
What are the adverse effects of HMG-COA reductase inhibitors? Ans:
Elevations in liver enzymes or liver disease.
Mild and transient GI disturbances
Myopathy (muscle pain) possibly leading to increased serious
rhabdomyolysis.
What are the functions of bile acid sequestrants? Ans: Example:
Cholestyramine (Questran)
Bind and remove bile acid in small intestine; promotes excretion, decreases
LDL.
Adjunct to statins
© 2025 All rights reserved
, 2 | Page
How would you administer bile acid sequestrants? Ans: PO; powdered form
Take with food and water; choking hazard when dry
Other med: Take 1 hour before or 4-6 hours after meals
What are the adverse effects of bile acid sequestrants? Ans: Nausea
Bloating
Constipation
Flatulence
What are the functions of niacin (nicotinic acid)? Ans: Reduce metabolism or
catabolism of cholesterol and triglycerides.
How would you administer niacin (nicotinic acid)? Ans: PO: Start low and
increase slowly
Take small dose of NSAID to decrease flushing
Take with meals
Other medications should be taken 1 hour before or 4 to 6 hours after meals
to avoid interference with absorption.
What are the adverse effects of niacin (nicotinic acid)? Ans: Flushing
Pruritis
GI distress
Hepatotoxic
© 2025 All rights reserved
