1 | Page
EDAPT: NCLEX Readiness:
Pharmacological and Parenteral Therapies
Part 2 Questions and Answers Latest Update
For each blood transfusion reaction, match the blood transfusion reaction
to the prevention strategy. Ans: Acute hemolytic reaction - Confirm that the
blood to be transfused is compatible with the client's blood type.
Febrile reaction - Consider leukocyte-reduced blood products.
Mild allergic reaction - Consider premedication with diphenhydramine.
Circulatory overload reaction - Adjust transfusion volume and slow the flow
rate.
A nurse is caring for a client who is prescribed one unit of packed red blood
cells to treat anemia. Pre-infusion vital signs are T 101.2 °F (38.4 °C), pulse
104, blood pressure 124/76, and respiratory rate 20. Which action should
the nurse take? Ans: Delay starting the transfusion and contact the
healthcare provider.
Which items should be checked during the verification process? Select all
that apply. Ans: Correct blood product based on the prescription
Expiration date on blood product bag
Client's name and date of birth
After reviewing the electronic health record, which information should be
clarified by the nurse? Ans: Laboratory values
© 2025 All rights reserved
, 2 | Page
The client asks the nurse which type of packed red blood cells are
acceptable for transfusion. The nurse responds that the client can receive
__________ blood products. Ans: O negative
If the nurse were to transfuse O positive blood to a client whose blood type
is O negative, the client is likely to experience a __________ caused by
__________. Ans: Acute hemolytic reaction
RBC destruction
The nurse is providing preoperative education to a client who will undergo a
left hip arthroplasty in 3 weeks. The client asks the nurse if they will need a
blood transfusion after the surgery. Since the client has a very rare blood
type, the nurse recommends the client consider __________. Ans: Elective
phlebotomy
The nurse is preparing to administer one unit of packed red blood cells to
client and has just completed the verification process. Place the steps the
nurse should take to transfuse the blood into the correct order. Ans: 1.
Spike the normal saline bag and prime the Y tubing.
2. Close the clamp that leads to the normal saline bag.
3. Spike the blood bag, open the upper clamp, and allow blood to flow
through the tubing.
4. Start the transfusion slowly for 15 minutes.
5. Obtain vital signs and compare them to baseline.
The charge nurse is observing a nurse during orientation who is
administering a blood transfusion. Which action taken by the nurse would
require the charge nurse to intervene? Ans: Prepares to administer
cefotaxime intravenously in the port closest to the insertion site.
The nurse is caring for several clients who need blood component
transfusions. Match the client to the appropriate component to be
© 2025 All rights reserved
, 3 | Page
transfused. Ans: Packed red blood cells - A client whose hemoglobin and
hematocrit are low following a bowel resection surgery
Fresh frozen plasma - A client with liver disease and a vitamin K deficiency
Platelets - A client who has thrombocytopenia
Albumin - A client who has hypovolemic shock following a motor vehicle
accident
The nurse reviews laboratory findings for a client with advanced liver
disease. Identify if each blood product should be requested or not requested
from the primary healthcare provider. Select one answer in each row. Ans:
Request:
Packed red blood cells
Fresh frozen plasma
Do Not Request:
Platelets
Whole blood
Cryoprecipitates
The nurse assesses a client admitted to the emergency department after a
motor vehicle accident. Findings include pulse 114 beats/minute, blood
pressure 84/45 (MAP 58) mm Hg, and pulse oximetry reading 93% on room
air. Laboratory data reveals a hemoglobin level of 7.5 g/dL (reference range
14-18 g/dL).
The nurse determines that __________ is the most concerning finding,
__________ is the most likely cause, and __________ is the priority action,
followed by the administration of __________. Ans: Blood pressure
© 2025 All rights reserved
EDAPT: NCLEX Readiness:
Pharmacological and Parenteral Therapies
Part 2 Questions and Answers Latest Update
For each blood transfusion reaction, match the blood transfusion reaction
to the prevention strategy. Ans: Acute hemolytic reaction - Confirm that the
blood to be transfused is compatible with the client's blood type.
Febrile reaction - Consider leukocyte-reduced blood products.
Mild allergic reaction - Consider premedication with diphenhydramine.
Circulatory overload reaction - Adjust transfusion volume and slow the flow
rate.
A nurse is caring for a client who is prescribed one unit of packed red blood
cells to treat anemia. Pre-infusion vital signs are T 101.2 °F (38.4 °C), pulse
104, blood pressure 124/76, and respiratory rate 20. Which action should
the nurse take? Ans: Delay starting the transfusion and contact the
healthcare provider.
Which items should be checked during the verification process? Select all
that apply. Ans: Correct blood product based on the prescription
Expiration date on blood product bag
Client's name and date of birth
After reviewing the electronic health record, which information should be
clarified by the nurse? Ans: Laboratory values
© 2025 All rights reserved
, 2 | Page
The client asks the nurse which type of packed red blood cells are
acceptable for transfusion. The nurse responds that the client can receive
__________ blood products. Ans: O negative
If the nurse were to transfuse O positive blood to a client whose blood type
is O negative, the client is likely to experience a __________ caused by
__________. Ans: Acute hemolytic reaction
RBC destruction
The nurse is providing preoperative education to a client who will undergo a
left hip arthroplasty in 3 weeks. The client asks the nurse if they will need a
blood transfusion after the surgery. Since the client has a very rare blood
type, the nurse recommends the client consider __________. Ans: Elective
phlebotomy
The nurse is preparing to administer one unit of packed red blood cells to
client and has just completed the verification process. Place the steps the
nurse should take to transfuse the blood into the correct order. Ans: 1.
Spike the normal saline bag and prime the Y tubing.
2. Close the clamp that leads to the normal saline bag.
3. Spike the blood bag, open the upper clamp, and allow blood to flow
through the tubing.
4. Start the transfusion slowly for 15 minutes.
5. Obtain vital signs and compare them to baseline.
The charge nurse is observing a nurse during orientation who is
administering a blood transfusion. Which action taken by the nurse would
require the charge nurse to intervene? Ans: Prepares to administer
cefotaxime intravenously in the port closest to the insertion site.
The nurse is caring for several clients who need blood component
transfusions. Match the client to the appropriate component to be
© 2025 All rights reserved
, 3 | Page
transfused. Ans: Packed red blood cells - A client whose hemoglobin and
hematocrit are low following a bowel resection surgery
Fresh frozen plasma - A client with liver disease and a vitamin K deficiency
Platelets - A client who has thrombocytopenia
Albumin - A client who has hypovolemic shock following a motor vehicle
accident
The nurse reviews laboratory findings for a client with advanced liver
disease. Identify if each blood product should be requested or not requested
from the primary healthcare provider. Select one answer in each row. Ans:
Request:
Packed red blood cells
Fresh frozen plasma
Do Not Request:
Platelets
Whole blood
Cryoprecipitates
The nurse assesses a client admitted to the emergency department after a
motor vehicle accident. Findings include pulse 114 beats/minute, blood
pressure 84/45 (MAP 58) mm Hg, and pulse oximetry reading 93% on room
air. Laboratory data reveals a hemoglobin level of 7.5 g/dL (reference range
14-18 g/dL).
The nurse determines that __________ is the most concerning finding,
__________ is the most likely cause, and __________ is the priority action,
followed by the administration of __________. Ans: Blood pressure
© 2025 All rights reserved
