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COGS 17 Midterm 2 UCSD Johnson W18 Latest Exam and All Correct Answers 2026 Updated.

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Visual Receptors - Answer Contain photopigment molecules that react to light Spontaneous, graded release of NT Isomerization - Answer Converting light into neural signal: Causes Na+/Ca++ gates to close, increasing receptor's polarity, decreasing NT release Outer Segment - Answer This portion of receptors is composed of lamellae with embedded photopigment Photopigment - Answer Molecules that react to light (made of opsin) Opsin - Answer Long protein chain, makes up photopigment Changes color ("bleached") when retinal detaches Retinal - Answer Short lipid segment, synthesized from Vitamin A, attached to opsin When absorbs photon, changes shape and detaches from opsin Photopigment Regeneration - Answer Recombination of retinal and opsin using enzymes from pigment epithelium; takes time Light Adapted - Answer Hard to see indoors after bright sunlight; as the photopigment regenerates, sensitivity is restored Dark Adapted - Answer Hard to see just after turning off the lights; as the photopigment regenerates, sensitivity is restored Retina - Answer Composed of neurons, multi-layered, covering rear, inner wall of eyeball

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COGS 17 Midterm 2 UCSD Johnson
W18 Latest Exam and All Correct
Answers 2026 Updated.
Visual Receptors - Answer Contain photopigment molecules that react to light



Spontaneous, graded release of NT



Isomerization - Answer Converting light into neural signal:



Causes Na+/Ca++ gates to close, increasing receptor's polarity, decreasing NT release



Outer Segment - Answer This portion of receptors is composed of lamellae with embedded
photopigment



Photopigment - Answer Molecules that react to light (made of opsin)



Opsin - Answer Long protein chain, makes up photopigment



Changes color ("bleached") when retinal detaches



Retinal - Answer Short lipid segment, synthesized from Vitamin A, attached to opsin



When absorbs photon, changes shape and detaches from opsin



Photopigment Regeneration - Answer Recombination of retinal and opsin using enzymes
from pigment epithelium; takes time



Light Adapted - Answer Hard to see indoors after bright sunlight; as the photopigment
regenerates, sensitivity is restored



Dark Adapted - Answer Hard to see just after turning off the lights; as the photopigment
regenerates, sensitivity is restored



Retina - Answer Composed of neurons, multi-layered, covering rear, inner wall of eyeball

,Receptors - Answer Rods and Cones, rearmost layer of retina



Rods - Answer Larger, in periphery, ~120 million/eye



Cones - Answer Smaller, dispersed throughout retina, ~ 6 million/eye



Fovea - Answer Small central area of high conc. of cones (no rods); for detail resolution



Very Low Convergence, 1:1 ganglions.



Bipolars - Answer Postsynaptic to receptors, spontaneous firing, graded potentials, releases
excitatory NT



Ganglions - Answer Postsynaptic to bipolars, action potentials



Axons form Optic Nerve



Blind Spot - Answer Where Optice Nerve leaves eye & blood vessels enter/leave; No
receptors



Optic Disk - Answer aka Blind Spot



Interneurons - Answer Perpendicular to pathway, influence interactions between above
neurons



Horizontals - Answer Graded potentials, mostly inhibitory NT, modify interface of receptors
and bipolars



Amacrines - Answer Graded potentials, mostly inhibitory NT, modify interface of Bipolars and
Ganglions



(many kinds)



Pigment Epithelium - Answer Rearmost layer of (non-neural) cells; feeds/recycles from
receptors; helps reflect/maximize light



Off - Answer Light turns receptor cells...

, On - Answer Darkness turns receptors cells...



Dark Current - Answer In the absence of stimulation, Receptor's Na+ gates open, Na+ flows
in and out, Ca++ gates open, causing continuous release of NT, Ca++ gates actively pumped out



Dark - Answer In (the dark/bright light/dim light), receptors release inhibitory NT to prevent
Bipolars from triggering Ganglions, so Ganglions (by not firing) report: "dark/bright/dim"



Bright Light - Answer In (the dark/bright light/dim light), receptors are shut down, don't
inhibit bipolars, bipolars spontaneously release excitatory NT to pass Ganglion's threshold,
ganglions report: "dark/bright/dim"



Dim Light - Answer In (the dark/bright light/dim light), receptor's spontaneous release is
decreased so bipolars only somewhat inhibited, release enough NT to sometimes trigger
ganglions



Connectivity Patterns - Answer Critical role in information-transmission functions



Convergence in Retina - Answer Individual receptors synapse onto multiple ganglions



Rods: High, 120:1

Cones: Low, 6:1.



Accounts for acuity and sensitivity differences between rods/cones



Acuity - Answer Detail resolution; high in cones, low in rods



Sensitivity - Answer In dim light, rods are more likely to trigger ganglions (bc more rods per
ganglion than cones - summation)



Receptive Field (RF) - Answer Set of Receptors whose activity influences activity of target cell
(any downstream cell)



Size/type determined by patterns of convergence and lateral influences



Large Receptive Field - Answer Ganglions along path from converging rods have a
(large/small receptive field)

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