NURS6630 -NURS 6630 PSYCHOPHARMACOLOGY MIDTERM EXAM 2 VERSIONS
ACTUAL MIDTERM EXAM SUMMER QRT| MOST RECENT WALDEN
UNIVERSITY|AGRADED
Serotonin regulates - CORRECT ANSWER Mood, emotion, feeding, and
reproductive behavior
QUESTION : This class of antidepressants binds to presynaptic SERT and inhibits
them from reuptake of serotonin to increase levels in the synaptic cleft to bind
with postsysnaptic 5HT2 receptors - CORRECT ANSWER SSRIs
QUESTION : First line therapy for MDD due to milder side effect profiles -
CORRECT ANSWER SSRIs
QUESTION : Six Common SSRIs - CORRECT ANSWER citalopram,
escitalopram, fluoxetine, fluvoxamine, sertraline, paroxetine
QUESTION : Onset of therapeutic benefit from SSRIs - CORRECT ANSWER
4-6 weeks
QUESTION : In addition to MDD, SSRIs also treat - CORRECT ANSWER
Chronic Anxiety, PTSD, OCD, and eating disorders (bulimia)
QUESTION : Five Common side effects of SSRIs include - CORRECT
ANSWER Anxiety, insomnia, GI distress, sexual dysfunction (ED), SIADH
UPDATED exam 2026
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QUESTION : Severe side effect of SSRIs in children/adolescents under age 25
years old - CORRECT ANSWER suicidal ideation
QUESTION : Life threatening adverse effect of SSRIs, especially when used in
combination with other serotonergic drugs (SNRIs, TCAs, MAOIs, etc.) -
CORRECT ANSWER Serotonin Syndrome
QUESTION : Excess accumulation of serotonin resulting in overstimulation of
the nervous system - CORRECT ANSWER Serotonin Syndrome
QUESTION : Seven symptoms of Serotonin Syndrome - CORRECT
ANSWER Flushing, hyperthermia, agitation, muscle rigidity, seizure, coma,
HYPERreflexia
QUESTION : The treatment for serotonin syndrome - CORRECT ANSWER
Cyproheptadine (5-HT2 receptor antagonist)
QUESTION : Cyproheptadine treats serotonin syndrome by - CORRECT
ANSWER blocking 5-HT2 receptors (serotonin antagonist)
QUESTION : When SSRIs or SNRIs are stopped abruptly, common symptoms of
withdrawal include - CORRECT ANSWER Irritability, headaches, and
insomnia
QUESTION : Medicine specific side effect of citalopram - CORRECT
ANSWER Prolonged QT interval (normal=0.4.-0.44 seconds)
UPDATED exam 2026
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QUESTION : This SSRI is pregnancy category D due to associations with
congenital heart defects - CORRECT ANSWER Paroxetine
QUESTION : All SSRIs but paroxetine (D) are pregnancy category - CORRECT
ANSWER C
QUESTION : Three SSRIs that are inhibitors of Cytochrome P450 enzymes -
CORRECT ANSWER fluoxetine, fluvoxamine, and paroxetine
QUESTION : Five common SNRIs include - CORRECT ANSWER
duloxetine, venlafaxine, desvenlafaxine, milnacipran, levomilnacipran
QUESTION : This antidepressant class of medications works by binding to
presynaptic SERT and NET to inhibit them from reuptake of serotonin and
norepinephrine to increase their levels in the synaptic cleft - CORRECT
ANSWER SNRIs
QUESTION : In addition to MDD SNRIs treat - CORRECT ANSWER
Anxiety and neuropathic pain (peripheral neuropathy)
QUESTION : Medication specific indications of duloxetine: - CORRECT
ANSWER urinary incontinence and Fibromyalgia
UPDATED exam 2026