Discussion week 4 complete solution latest 2020

Ethical Dimensions of Research Research helps guide our practice. It contributes new knowledge to the nursing profession and helps improve patient care (Laureate Education, 2012d). We research to acquire knowledge and to identify the best practice of care. Research addresses the problems and questions into study or investigation (Polit & Beck, 2017). The research involves human, one of the basic concepts in research who contribute information in the study (Polit & Beck, 2017). Clinical research “aims to advance medical knowledge by studying people, either through direct interaction or through the collection and analysis of blood, tissues, or other samples” (National Institute of Child Health and Human Development, n.d.). However, it is crucial to consider the individual who volunteers to participate and involve in research. Research ethics provides guidelines to protect the person who volunteers and to preserve the integrity of the research. The guiding principles of ethics are the pursuing the protection of research participants. The Belmont Report outlines the three major principles for the ethical conduct of research with a human subject, these are based on respect for human dignity, beneficence, and justice (Schmith & Brown, 2012). In 2004, there was an ethical issue about the research into selective serotonin reuptake inhibitors (SSRI) such as Prozac, Paxil, and Zoloft use in childhood depression. The controversy heightens due to increasing the number of suicide and the Pitman case who was 12 years old and under the influence of Zoloft, a powerful psychotropic drug, when he killed his grandparents This study resource was shared via CourseH (Alliance for Human Research Protection, 2005). In addition, the drug company Pfizer failed to Zoloft suicide risk in NYT advertisement in 2004. The root of this dilemma is the variation in the experimental design. According to the FDA report, in two studies there were six suicide events in the Zoloft group and two in the placebo group. “After combining the two studies, of the children in the Zoloft group, 69% had a successful response, whereas 59% of the children in the placebo group experienced a successful response: not a large difference, but enough to make the headlines” (Leo, 2008). It is obvious that the marketing department was successful in its management of the negative information surrounding this study. Consequently, the study raises ethical issues by using the anti-psychotic drugs to a vulnerable group (children) of the population, the fault of peer reviewers to question the discrepancy in Zoloft study, and the authors that published the research.