This expert-verified Learning Module 2 for NUR 370 delivers over 70 detailed Q&A entries on essential topics including autonomic nervous system (ANS) regulation, stress physiology, immune response, and pain mechanisms. Designed for BSN and ABSN nursing students, it bridges foundational science with clinical pharmacology, helping learners understand systemic regulation, medication actions, and nursing implications.
The autonomic nervous system section explains the roles of the sympathetic (“fight or flight”) and parasympathetic (“rest and digest”) systems in regulating homeostasis. It details how neurotransmitters like norepinephrine, epinephrine, and acetylcholine interact with alpha, beta, muscarinic, and nicotinic receptors, and how adrenergic and cholinergic drugs work as agonists or antagonists for treating shock, asthma, urinary retention, and more.
Included pharmacologic agents:
Epinephrine and dopamine (adrenergic agonists)
Nonselective adrenergic blockers
Direct-acting cholinergic agonists
Anticholinergic agents (parasympatholytics)
In the stress and homeostasis section, the document covers:
HPA axis regulation
GAS (General Adaptation Syndrome): alarm, resistance, exhaustion
Acute vs. chronic stress impacts on immune function and health
Negative feedback systems and neural/endocrine integration during stress
The immune response module outlines:
Leukocyte types (T-cells, B-cells, macrophages, NK cells)
Lymphoid tissues (bone marrow, spleen, lymph nodes)
Cytokines and immune proteins like TNF, interleukins, interferons
Innate and adaptive immunity, including natural vs. artificial immunity (active/passive)
The final section focuses on pain physiology and pharmacology:
Types of pain: nociceptive, neuropathic, psychogenic
Pain fibers: A, A-delta, and C fibers
Gate Control Theory and the pain transmission pathway
Opioid receptor sites, opioid agonists (e.g., morphine), and opioid agonist-antagonists for moderate to severe pain management
Best suited for:
Nursing students studying pharmacology, pathophysiology, or neuro/immune systems
Learners preparing for NUR 370 exams or NCLEX coverage of ANS, pain, or immunity
Clinical prep on sympathetic vs. parasympathetic drug mechanisms
Comprehensive and exam-aligned, this Q&A guide makes it easy to grasp complex drug-receptor interactions, body-wide systemic responses, and foundational concepts critical to safe nursing care.
Keywords:
sympathetic system, parasympathetic drugs, adrenergic agonists, cholinergic receptors, HPA axis, stress response, immune defense, cytokines, leukocytes, pain fibers, gate control theory, opioid agonists, nociceptive pain, NUR 370
Content preview
NUR 370 LM2
Autonomic Nervous System - 🧠 ANSWER ✔✔Regulate homeostasis
through CNS, PNS, and endocrine
Nerve impulse in PNS to CNS
CNS impulses to stimulate organs, glands, muscles
Sympathetic Nervous System - 🧠 ANSWER ✔✔Fight or flight
Increase HR, BP, RR, broncho + pupil dilation, glucose breakdown
Decrease elimination, digestion, reproduction
CNS in thoracic and lumbar stimulate nerve ganglia
NT released, mostly norepinephrine and epinephrine
, Adrenergic/Sympathetic Receptors - 🧠 ANSWER ✔✔Alpha and beta
receptors respond to epinephrine and norepinephrine -> different receptors
(A1, A2, B1, B2) have different responses
Alpha and Beta Adrenergic Agonists - 🧠 ANSWER ✔✔Treat: hypotension
(decrease BP), shock, bronchospasm, asthma
Action:
Adverse Effects: Sympathetic NS stimulation
Epinephrine (AB Adrenergic Agonsit) - 🧠 ANSWER ✔✔Causes
vasoconstriction, increased HR + BP, bronchodilation
Treats: bronchospasm (asthma), anaphylaxis
Dopamine (AB Adrenergic Agonist) - 🧠 ANSWER ✔✔Increases HR + BP,
preserves blood flow to kidneys
Treats: Shock
Nonselective Adrenergic Blocking Agents - 🧠 ANSWER ✔✔Treats: Cardiac
issues like hypertension and tachycardia
Action: competitive inhibitor of A1 and B receptors in SNS