NR565 Advanced Pharmacology
Midterm Exam Study Guide Question
and answers verified to pass
2025/2026
Drugs that APRNs can prescribe - correct answer ✔Schedule 3-5 drugs
Determined by State Boards of Nursing, Medicine, and Pharmacy - correct answer ✔Prescriptive
authority regulation
Leads to fewer treatment options for patients, requiring them to find providers with authority - correct
answer ✔Limited prescriptive authority impact
Understanding prescribed drugs, their effects, contraindications, and ensuring correct dosages - correct
answer ✔Key responsibilities of prescribing
Acronym for CYP450 enzyme inducers: Barbiturates, St. John's Wort, Carbamazepine, Rifampin, Alcohol,
Phenytoin, Griseofulvin, Phenobarbital, Sulfonylureas - correct answer ✔BSCRAP GPS Incudes Rage
Amount of active drug reaching systemic circulation from administration site - correct answer
✔Bioavailability
Include forgetfulness, lack of planning, cost, dissatisfaction, and altered dosing - correct answer
✔Reasons for medication nonadherence
Absorption is slow in neonates due to low muscle blood flow; absorption becomes rapid in early infancy
- correct answer ✔IM administration in neonates and infants
, Gastric emptying time is prolonged and irregular in early infancy, affecting drug absorption - correct
answer ✔Oral administration in neonates/infants
Based on body surface area (BSA) calculation - correct answer ✔Dosage determination for pediatric
patients
Steps include defining the problem, setting therapeutic objectives, choosing treatment, verifying its
suitability, starting treatment, giving information, and monitoring treatment - correct answer ✔Guiding
principles for prescribers
Examples include Valproate, Isoniazid, Sulfonamides, Amiodarone, Chloramphenicol, Ketoconazole,
Grapefruit juice, Quinidine - correct answer ✔CYP450 inhibitors
Basis for prescribing decisions, considering drug interactions and effects on target receptors - correct
answer ✔Pharmacokinetics and pharmacodynamics
Tool identifying inappropriate medication use in older adults, cautioning against certain drugs and
interactions - correct answer ✔Beer's Criteria
Include adverse drug events, increased healthcare interactions, cognitive impairment, reduced
adherence, falls, and mortality - correct answer ✔Impacts of polypharmacy
They decrease medication metabolism - correct answer ✔CYP450 inhibitors function
May cause toxicity if enzymes are inactive or ineffectiveness if enzymes are overactive - correct answer
✔CYP450 inhibitors consequences
Occurs when CYP2D6 alleles have inactivating mutations, leading to enzyme synthesis with impaired or
no activity - correct answer ✔Poor metabolism phenotype
Midterm Exam Study Guide Question
and answers verified to pass
2025/2026
Drugs that APRNs can prescribe - correct answer ✔Schedule 3-5 drugs
Determined by State Boards of Nursing, Medicine, and Pharmacy - correct answer ✔Prescriptive
authority regulation
Leads to fewer treatment options for patients, requiring them to find providers with authority - correct
answer ✔Limited prescriptive authority impact
Understanding prescribed drugs, their effects, contraindications, and ensuring correct dosages - correct
answer ✔Key responsibilities of prescribing
Acronym for CYP450 enzyme inducers: Barbiturates, St. John's Wort, Carbamazepine, Rifampin, Alcohol,
Phenytoin, Griseofulvin, Phenobarbital, Sulfonylureas - correct answer ✔BSCRAP GPS Incudes Rage
Amount of active drug reaching systemic circulation from administration site - correct answer
✔Bioavailability
Include forgetfulness, lack of planning, cost, dissatisfaction, and altered dosing - correct answer
✔Reasons for medication nonadherence
Absorption is slow in neonates due to low muscle blood flow; absorption becomes rapid in early infancy
- correct answer ✔IM administration in neonates and infants
, Gastric emptying time is prolonged and irregular in early infancy, affecting drug absorption - correct
answer ✔Oral administration in neonates/infants
Based on body surface area (BSA) calculation - correct answer ✔Dosage determination for pediatric
patients
Steps include defining the problem, setting therapeutic objectives, choosing treatment, verifying its
suitability, starting treatment, giving information, and monitoring treatment - correct answer ✔Guiding
principles for prescribers
Examples include Valproate, Isoniazid, Sulfonamides, Amiodarone, Chloramphenicol, Ketoconazole,
Grapefruit juice, Quinidine - correct answer ✔CYP450 inhibitors
Basis for prescribing decisions, considering drug interactions and effects on target receptors - correct
answer ✔Pharmacokinetics and pharmacodynamics
Tool identifying inappropriate medication use in older adults, cautioning against certain drugs and
interactions - correct answer ✔Beer's Criteria
Include adverse drug events, increased healthcare interactions, cognitive impairment, reduced
adherence, falls, and mortality - correct answer ✔Impacts of polypharmacy
They decrease medication metabolism - correct answer ✔CYP450 inhibitors function
May cause toxicity if enzymes are inactive or ineffectiveness if enzymes are overactive - correct answer
✔CYP450 inhibitors consequences
Occurs when CYP2D6 alleles have inactivating mutations, leading to enzyme synthesis with impaired or
no activity - correct answer ✔Poor metabolism phenotype
