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CCRN Neonatal – Questions and Answers | Critical Care Nursing | 2026–2027 A+ Grade

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This document provides a comprehensive set of CCRN Neonatal practice questions with detailed answers, covering essential concepts in neonatal critical care. Key topics include neonatal assessment, respiratory and cardiovascular management, fluid and electrolyte balance, pharmacology, infection control, and evidence-based interventions for critically ill neonates. Tailored for the 2026–2027 academic year, this guide supports exam preparation, skill reinforcement, and achieving an A+ level performance on the CCRN Neonatal certification.

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CCRN neonatal questions and answers
2026\2027 A+ Grade

Fetal fibronectin
- correct answer biochemical marker useful for predicting preterm birth within 2 weeks



placental α-microglobulin-1 (PAMG-1) protein
- correct answer presence indicates rupture of membranes



Fetal heart rate variability
- correct answer best indicator of fetal oxygenation status (absence of metabolic acidemia)



Biophysical profile
- correct answer -fetal tone

-fetal breathing

-fetal movement

-nonstress test

-amniotic fluid volume



Late decelerations
- correct answer transient response to hypoxemia during contractions



Variable decelerations
- correct answer cord compression

-tx: amnioinfusion, intrauterine pressure catheter



Maternal serum α-fetoprotein
- correct answer -Elevated: neural tube defect, abdominal wall defect, EA/duodenal atresia

, -Decreased: Down syndrome



Target preductal sat after birth
- correct answer -1 minute 60-65%

-2 minutes 65-70%

-3 minutes 70-75%

-4 minutes 75-80%

-5 minutes 80-85%

-10 minutes 85-90%



Arterial cord blood gas
- correct answer reveals the metabolic status of the fetus before delivery and strongly correlates with
perinatal asphyxia



Turner syndrome
- correct answer -SGA with a broad chest

-widely spaced nipples

-edema of the extremities

-short webbed neck



Trisomy 13
- correct answer -cutis aplasia

-overlapping digits

-low-set ears, cleft palate

-microcephaly

-microphthalmia

-polydactyly

-rocker bottom feet

-numerous organ abnormalities (including cardiac)

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