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HESI A2 Anatomy and Physiology – Nursing Entrance Exam Preparation, Academic Year 2026 – Complete Review and Practice Material

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This document covers all essential topics in anatomy and physiology for the HESI A2 exam, including body systems, cellular structure, organ function, and physiological processes. It provides review notes, practice questions, and explanations to help students prepare effectively for the HESI A2 entrance exam. The material is aligned with current HESI standards for comprehensive exam preparation. Keywords: HESI A2 Anatomy and physiology Body systems Cell structure Organ function Skeletal system Muscular system Cardiovascular system Respiratory system Nervous system Digestive system Endocrine system Urinary system Reproductive system Physiological processes

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HESI A2 ANATOMY AND PHYSIOLOGY | LATEST UPDATE
| QUESTIONS AND VERIFIED ANSWERS |
GRADED A+

What is histology?
- ANSWER: The study of tissues

What is a tissue?
- ANSWER: A group of cells that act together to perform a specific function.

What are the fundamental tissues?
- ANSWER: Epithelial
Connective
Muscle
Nerve
(Elephants Can Make News)

What is the function of epithelial cells?
- ANSWER: Cover, line, and protect the body and the internal organs.

What is the function of connective tissue?
- ANSWER: Framework of the body. Provides support and structure to organs.

What is neuroglia?
- ANSWER: The neurons and connective tissue cells that compose nerve tissue.

What ability does muscle tissue have?
- ANSWER: Ability to contract and shorten.

What is muscle tissue classified as?
- ANSWER: Voluntary(skeletal muscles) and involuntary(smooth & cardiac)

What is meiosis?
- ANSWER: The cell division that takes place in the gonads, i.e. the ovaries and testes.

,What two layers compose the skin?
- ANSWER: Epidermis and dermis.

What is the epidermis?
- ANSWER: The outermost protective layer of dead keratinized epithelial cells.

What is the dermis?
- ANSWER: The underlying layer of connective tissue with blood vessels, nerve
endings, and the associated skin tissues.

What are the layers of the epidermis?
- ANSWER: Corneum
Lucidum
Granulosum
Germivatum ( basale & spinosum)
Mnemonic: Candy Lions Growl Great.

What does the protein pigment melanin protect against?
- ANSWER: Radiation from the Sun

What is the dermis composed of?
- ANSWER: Fibrous connective tissue with nerve endings, blood vessels, sensory nerve
endings, hair follicles, and glands.

What are the 2 types of sweat glands?
- ANSWER: ecrine & apocrine

What do ecrine sweat glands produce?
- ANSWER: Sweat. Regulate body temperature.

What do apocrine sweat glands produce?
- ANSWER: Secretions contain bits of cytoplasm from cells, attracting bacteria that
produces body odor.

What do sebaceous glands secrete?
- ANSWER: They secrete sebum through the hair follicles, which lubricates the skin and
prevents drying.

, What secretion produces oil?
- ANSWER: Holocrine secretion.

What are sebaceous glands prone to during adolescence?
- ANSWER: Becoming clogged and attracting bacteria.

What protein composes the hair and skin?
- ANSWER: Keratin

What makes the body's framework?
- ANSWER: Bone, cartilage, ligaments & joints.

What are the functions of the skeletal system?
- ANSWER: Support, movement, blood cell formation, protection of internal organs,
detoxification, muscle attachment, mineral storage. *A MIME BATHED SEALS
SINGING "MY PONY"*

How are bones classified?
- ANSWER: By shape.
Long
Short
flat
irregular
sesamoid
*LEMURS SING SALSA FOR INDIANS*

What is the name for the cells that compose compact bone?
- ANSWER: Osteoblasts

What occurs to osteoblasts when they become fixed in the dense bone matrix?
- ANSWER: They stop dividing but continue to maintain body tissues as osteocytes.

How many bones make up the axial skeleton?
- ANSWER: 28 bones of the skull. 14-facial, 14-cranium.

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