NR 546 MIDTERM REVIEW MIDTERM AND FINAL EXAM
REVIEW NOTES WITH KEY CONCEPTS EXPLAINED SIMPLY
Neuroscience matters - correct answer -Neuroscience is the foundation for mental health
prescribing, especially as the future moves toward symptom-based prescribing rather than
selecting a drug class based on a diagnosis. Know what area of the brain is associated with
presenting symptoms AND how the medication works on that area of the brain to treat that
symptom (the medication mechanism of action)
Functional neuroanatomy - correct answer -Classifying how regions within the nervous system
relate to psychology and behavior.
If a particular area of the brain is affected, what is the expected response? What symptoms
would you expect to see? Link the assessment to the affected brain area.
Ethical Issues - correct answer -course Explore section and readings
Epigenetics - correct answer -the study of influences on gene expression that occur without a
DNA change
Why is epigenetics important? - correct answer -Involved in switching genes on and off
i.e. controlling transcription/translation
How does epigenetics impact a person's mental health? - correct answer -
Genetics - correct answer -The scientific study of heredity
How does the CYP450 affect pharmacodynamics and pharmacokinetics? - correct answer -
, What are some very common/concerning interactions? - correct answer -Also see Stahl Ch 2.
Incidence of mental illness - correct answer -what factors are increasing the incidence? This is
covered in the course Explore section
CYP450 - correct answer --Enzyme family most important in metabolizing drugs
-Always available in the liver
-Evolved to eliminate toxic chemicals from plants
-Function can be altered by alcohol & barbiturates
CYP450 inducers - correct answer -Kenytoin Rides Shotgun in Barbie's Crazy Girly Motor Car
phenytoin
rifampin
st. john's wart
barbiturates
chronic alcohol use
griseofulvan
modafinil
carbamazepine
How does an inhibitor or inducer affect medication efficacy? - correct answer -
CYP450 inhibitors - correct answer -CRACK AMIGOS
Cimetidine
Ritonavir (protease inhibitor)
REVIEW NOTES WITH KEY CONCEPTS EXPLAINED SIMPLY
Neuroscience matters - correct answer -Neuroscience is the foundation for mental health
prescribing, especially as the future moves toward symptom-based prescribing rather than
selecting a drug class based on a diagnosis. Know what area of the brain is associated with
presenting symptoms AND how the medication works on that area of the brain to treat that
symptom (the medication mechanism of action)
Functional neuroanatomy - correct answer -Classifying how regions within the nervous system
relate to psychology and behavior.
If a particular area of the brain is affected, what is the expected response? What symptoms
would you expect to see? Link the assessment to the affected brain area.
Ethical Issues - correct answer -course Explore section and readings
Epigenetics - correct answer -the study of influences on gene expression that occur without a
DNA change
Why is epigenetics important? - correct answer -Involved in switching genes on and off
i.e. controlling transcription/translation
How does epigenetics impact a person's mental health? - correct answer -
Genetics - correct answer -The scientific study of heredity
How does the CYP450 affect pharmacodynamics and pharmacokinetics? - correct answer -
, What are some very common/concerning interactions? - correct answer -Also see Stahl Ch 2.
Incidence of mental illness - correct answer -what factors are increasing the incidence? This is
covered in the course Explore section
CYP450 - correct answer --Enzyme family most important in metabolizing drugs
-Always available in the liver
-Evolved to eliminate toxic chemicals from plants
-Function can be altered by alcohol & barbiturates
CYP450 inducers - correct answer -Kenytoin Rides Shotgun in Barbie's Crazy Girly Motor Car
phenytoin
rifampin
st. john's wart
barbiturates
chronic alcohol use
griseofulvan
modafinil
carbamazepine
How does an inhibitor or inducer affect medication efficacy? - correct answer -
CYP450 inhibitors - correct answer -CRACK AMIGOS
Cimetidine
Ritonavir (protease inhibitor)
