NM717 FINAL CERTIFICATION EVALUATION SET
2026 COMPLETE QUESTIONS AND ANSWERS
◉ Fluconazole big take aways. Answer: Used for yeast/fungal
infections
CYP450 interactions b/c it works by inhibiting fungal CYP450
Can cause HA, GI
Avoid with hx of heart arrhythmia, liver/kidney disease
lots of drug interactions
Can use in pregnancy and lactation but ideally topical
◉ Acylcovir big take aways. Answer: Used to treat herpes
genitalia/simplex/zoster, and varicella
crosses placenta and enters breastmilk
most of metabolism is in liver and excretion in urine
inhibits viral DNA sythesis
Does not cure latent herpes virus
SE: n/v, diarrhea, HA, skin rash, acute renal failure (rare with PO)
Can use in pregnancy and lactation
Take with full glass of water
**Valacyclovir: prodrug
,Famciclovir: prodrug, both of these have better bioavailability than
acylclovir
◉ Alendronate take aways. Answer: Bisphosphonate used for
prevention and treatment of osteoporosis
3-6 months till max absorption
Dont take with food, coffee, calcium (wait 2hrs), or orange juice
it inhibits the activity of osteoclasts, which reduces bone resportion
SE: GI problems, esophageal ulcers/erosions,
hypocalcemia, osteonecrosis of the jaw,
Need to stay upright x30min after taking it
avoid with renal impairment, hypocalcemia
Take in the morning with 8oz of water, no other drinks, foods, meds
for 30-60min
◉ Oxybutynin take aways. Answer: Antimuscarinic Anticholinergic
Used for overactive bladder
Can cause anticholinergic SE: dry mouth, blurred vision,
constipation, tachycardia, urinary retention, drowsiness, impaired
sweating, confusion
Drug interactions with CYP3A4 inhibitors
Take with full glass of water, can take with or without food, caution
with overheating
,Caution with uncontrolled narrow-angle glaucoma, gastric or
urinary retention, esophageal disease, liver/kidney disease, heart
disease, HTN, older adults
◉ Atorvastatin take aways. Answer: 1st line treatment for reduction
of LDL
decreases cholesterol production in the liver and increases LDL
reuptake in liver.
AE: muscle pain, rhabdomyolysis: if they have severe muscle pain or
weakness, or dark colored urine check creatinine kinase levels
GI: abdominal pain, constipation, diarrhea, nausea
Lots of drug interactions, including warfarin, digoxin, and CYP3A4
inhibitors
Contraindicated in pregnancy or with liver disease
◉ Tamoxifen take aways. Answer: Selective Estrogen Receptor
Modulator (SERM)
Used to treat and prevent estrogen receptor positive breast cancer
primarily excreted in feces
AE: VTE, endometrial cancer, hot flashes, nausea, vaginal dryness,
menstrual irregularities, weight gain, bone loss if premenopausal
◉ Pitocin Take Aways. Answer: Onset: 3-4min, steady state in 30-
40min, half life in 6-10min
, IV: subsides in 1 hr after d/c
IM: duration of action for 2-3hrs
minimally crosses placenta
Risk for water intoxication
◉ Nitrous Take aways. Answer: 50/50 nitrous and O2
crosses placenta but rapidly eliminated
mostly breathed out
can cause N/V, megaloblastic anemia with low B12
◉ Betamethasone take aways. Answer: promotion of fetal lung
maturity
two 12mg doses 24hrs apart
if <34weeks AND first course was >7-14 days ago can give single
rescue course
◉ Magnesium Sulfate take aways. Answer: Anticonvulsant
seizure prophylaxis with (pre)eeclampsia
fetal neuroprotection if anticipating <32 week birth
short term (<48h) tocolytic
Usually IV: loading dose 4-6g in 100mL over 20-30min, then
maintenance 2g/hr x 12-24hrs
2026 COMPLETE QUESTIONS AND ANSWERS
◉ Fluconazole big take aways. Answer: Used for yeast/fungal
infections
CYP450 interactions b/c it works by inhibiting fungal CYP450
Can cause HA, GI
Avoid with hx of heart arrhythmia, liver/kidney disease
lots of drug interactions
Can use in pregnancy and lactation but ideally topical
◉ Acylcovir big take aways. Answer: Used to treat herpes
genitalia/simplex/zoster, and varicella
crosses placenta and enters breastmilk
most of metabolism is in liver and excretion in urine
inhibits viral DNA sythesis
Does not cure latent herpes virus
SE: n/v, diarrhea, HA, skin rash, acute renal failure (rare with PO)
Can use in pregnancy and lactation
Take with full glass of water
**Valacyclovir: prodrug
,Famciclovir: prodrug, both of these have better bioavailability than
acylclovir
◉ Alendronate take aways. Answer: Bisphosphonate used for
prevention and treatment of osteoporosis
3-6 months till max absorption
Dont take with food, coffee, calcium (wait 2hrs), or orange juice
it inhibits the activity of osteoclasts, which reduces bone resportion
SE: GI problems, esophageal ulcers/erosions,
hypocalcemia, osteonecrosis of the jaw,
Need to stay upright x30min after taking it
avoid with renal impairment, hypocalcemia
Take in the morning with 8oz of water, no other drinks, foods, meds
for 30-60min
◉ Oxybutynin take aways. Answer: Antimuscarinic Anticholinergic
Used for overactive bladder
Can cause anticholinergic SE: dry mouth, blurred vision,
constipation, tachycardia, urinary retention, drowsiness, impaired
sweating, confusion
Drug interactions with CYP3A4 inhibitors
Take with full glass of water, can take with or without food, caution
with overheating
,Caution with uncontrolled narrow-angle glaucoma, gastric or
urinary retention, esophageal disease, liver/kidney disease, heart
disease, HTN, older adults
◉ Atorvastatin take aways. Answer: 1st line treatment for reduction
of LDL
decreases cholesterol production in the liver and increases LDL
reuptake in liver.
AE: muscle pain, rhabdomyolysis: if they have severe muscle pain or
weakness, or dark colored urine check creatinine kinase levels
GI: abdominal pain, constipation, diarrhea, nausea
Lots of drug interactions, including warfarin, digoxin, and CYP3A4
inhibitors
Contraindicated in pregnancy or with liver disease
◉ Tamoxifen take aways. Answer: Selective Estrogen Receptor
Modulator (SERM)
Used to treat and prevent estrogen receptor positive breast cancer
primarily excreted in feces
AE: VTE, endometrial cancer, hot flashes, nausea, vaginal dryness,
menstrual irregularities, weight gain, bone loss if premenopausal
◉ Pitocin Take Aways. Answer: Onset: 3-4min, steady state in 30-
40min, half life in 6-10min
, IV: subsides in 1 hr after d/c
IM: duration of action for 2-3hrs
minimally crosses placenta
Risk for water intoxication
◉ Nitrous Take aways. Answer: 50/50 nitrous and O2
crosses placenta but rapidly eliminated
mostly breathed out
can cause N/V, megaloblastic anemia with low B12
◉ Betamethasone take aways. Answer: promotion of fetal lung
maturity
two 12mg doses 24hrs apart
if <34weeks AND first course was >7-14 days ago can give single
rescue course
◉ Magnesium Sulfate take aways. Answer: Anticonvulsant
seizure prophylaxis with (pre)eeclampsia
fetal neuroprotection if anticipating <32 week birth
short term (<48h) tocolytic
Usually IV: loading dose 4-6g in 100mL over 20-30min, then
maintenance 2g/hr x 12-24hrs
