Fetal Growth Restriction(100% Correct answers)
How do you define the term fetal growth restriction and small of gestational age? correct
answers1) FGR = <10%ile for gestational age
2) SGA = Newborns who are <10%ile weight for gestational age when they are born
What are the common etiologies of fetal growth restriction? correct answers1) Thrombophlic
diseases
2) Maternal malnutrition
3) Substance abuse
4) Twin gestation
5) Teratogen exposure
6) Infectious diseases
7) Genetic abnormalities
8) Placental and umbilical cord disease processes
What are some maternal disorders that cause fetal growth restriction? correct answersVascular
Related Disorders that cause hypercoagulable state = APLA syndrome, TTP/HUS, SLE, ect.
How does substance abuse impact fetal growth? correct answers1) Tobacco use causes 3.5 fold
increase in SGA
2) Alcohol (increased with 1-2 drinks daily)
3) Other substances include cocaine and narcotics
How does maternal malnutrition affect fetal growth? correct answers1) Poor protein intake
before 26 weeks associated with SGA
2) Severe caloric restriction only modest decreases in birth weight
How does multiple gestations affect fetal birth weight? correct answers1) Account for 2-3% live
births, associated with increased rate of SGA and preterm birth (25% for twins, 60% for triplets)
2) Monochorionic twins at risk of TTTS, increased risk of SGA
What are some teratogens that can impact fetal growth? correct answers1) Antineoplastic
medications (cyclophosphamide)
2) Antiepileptic medications (valproic acid)
3) Antithrombotic drugs (warfarin)
NOTE: Dependent on the drug dosage, length of exposure, timing of exposure.
What are some infectious diseases that affect fetal growth? correct answers1) Malaria accounts
for FGR worldwide
2) CMV
3) Rubella
4) Toxoplasmosis
5) Syphillis
6) Varicella
NOTE: Think TORCHES infections with FGR.
How do you define the term fetal growth restriction and small of gestational age? correct
answers1) FGR = <10%ile for gestational age
2) SGA = Newborns who are <10%ile weight for gestational age when they are born
What are the common etiologies of fetal growth restriction? correct answers1) Thrombophlic
diseases
2) Maternal malnutrition
3) Substance abuse
4) Twin gestation
5) Teratogen exposure
6) Infectious diseases
7) Genetic abnormalities
8) Placental and umbilical cord disease processes
What are some maternal disorders that cause fetal growth restriction? correct answersVascular
Related Disorders that cause hypercoagulable state = APLA syndrome, TTP/HUS, SLE, ect.
How does substance abuse impact fetal growth? correct answers1) Tobacco use causes 3.5 fold
increase in SGA
2) Alcohol (increased with 1-2 drinks daily)
3) Other substances include cocaine and narcotics
How does maternal malnutrition affect fetal growth? correct answers1) Poor protein intake
before 26 weeks associated with SGA
2) Severe caloric restriction only modest decreases in birth weight
How does multiple gestations affect fetal birth weight? correct answers1) Account for 2-3% live
births, associated with increased rate of SGA and preterm birth (25% for twins, 60% for triplets)
2) Monochorionic twins at risk of TTTS, increased risk of SGA
What are some teratogens that can impact fetal growth? correct answers1) Antineoplastic
medications (cyclophosphamide)
2) Antiepileptic medications (valproic acid)
3) Antithrombotic drugs (warfarin)
NOTE: Dependent on the drug dosage, length of exposure, timing of exposure.
What are some infectious diseases that affect fetal growth? correct answers1) Malaria accounts
for FGR worldwide
2) CMV
3) Rubella
4) Toxoplasmosis
5) Syphillis
6) Varicella
NOTE: Think TORCHES infections with FGR.
