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HESI A2 Anatomy & Physiology | 2026 Exam Q&A | 200+ Verified Questions | Muscles, Hormones, Brain, Bones, Organs

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This document contains over 200 expertly crafted and verified multiple-choice questions with answers for the 2026 HESI A2 Anatomy & Physiology exam. Structured in a flashcard-style Q&A format across 10 well-organized pages, it covers a wide range of anatomical and physiological topics that are highly relevant for students preparing for nursing and allied health program admissions. Core topics reviewed in the document include: Muscle physiology and skeletal structure (e.g., sarcomeres, ligaments vs. tendons, ossification, joint types) Endocrine system and hormonal regulation (e.g., cortisol, aldosterone, oxytocin, insulin, estrogen) Brain anatomy and nervous system function (e.g., cerebrum, cerebellum, medulla oblongata, afferent neurons, Wernicke's area) Digestive and urinary systems (e.g., bile, chyme, nephron, kidney function, cecum-to-anus flow) Respiratory and circulatory systems (e.g., alveoli gas exchange, pulmonary arteries, heart chambers and valves) Tissue types and cellular basics (e.g., epithelial, connective, stratum germinativum, monocytes, neutrophils) Reproductive system (e.g., estrogen’s role, sperm maturation, fallopian tube fertilization, placenta, hormone cycles) Skeletal labeling and movement terms (e.g., diaphysis, epiphysis, carpals, tarsals, abductors vs. adductors) This guide is highly valuable for: Nursing students (BSN, ADN, LPN) HESI A2 exam candidates Pre-nursing, pre-med, and allied health learners Students taking introductory anatomy & physiology courses Whether used for focused unit review or full-exam prep, the resource provides rich, accurate content to reinforce test-critical knowledge. Keywords: HESI A2 2026, anatomy and physiology, muscle tissue, hormones, sarcomeres, cerebrum, spinal cord, endocrine system, nephron, urinary system, digestive process, reproductive anatomy, bones, cartilage, joints, blood vessels, alveoli, reflex arc, nervous system, verified questions, nursing entrance exam

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Hesi A2 Anatomy and Physiology 2026
Exam Questions and Correct Answers |
New Update



Which is NOT a function of the digestive tract - 🧠ANSWER ✔✔perform gas

exchange


Endocrine system communicates - 🧠ANSWER ✔✔through hormones


Anatomical position - 🧠ANSWER ✔✔forward facing


Vitamin K is produced in - 🧠ANSWER ✔✔intestinal tract


Tissue doctor - 🧠ANSWER ✔✔histologist

, Erythropoiesis - 🧠ANSWER ✔✔red blood cell formation


Relationship between sarcomeres and muscle cells - 🧠ANSWER

✔✔muscle cells contain myofibrils, which in turn contain sarcomeres


Muscles produce contractions due to sliding action of - 🧠ANSWER

✔✔filaments


Simple reflexes travel through - 🧠ANSWER ✔✔spinal cord


Estrogen initiates - 🧠ANSWER ✔✔preparation of endometrium for

pregnancy

NOT a role of cortisol (produced in adrenal gland) - 🧠ANSWER

✔✔controlling motor impulses


Base of the skull - 🧠ANSWER ✔✔foramen magnum


Dendrite--->________, Axons----->__________ - 🧠ANSWER ✔✔toward,

away


Soleus muscle located in - 🧠ANSWER ✔✔leg


Hormones are responsible for - 🧠ANSWER ✔✔differentiation in cells


Sperm stored in - 🧠ANSWER ✔✔epididymis

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