Pharm Opioids- Nagelhout Exam Questions With
Correct Answers
What |are |the |3 |naturally |occurring |phenanthrenes? |- |CORRECT |ANSWER✔✔-1) |Morphine |--> |
HISTAMINE
2) |Codeine |---> |HISTAMINE
3) |Thebaine
What |are |the |5 |semisynthetic |phenanthrenes? |- |CORRECT |ANSWER✔✔-1) |heroin
2) |vicodin |(Hydrocodone) |
3) |dialudid |(hydromorphone)
4) |oxycodone |(oxycontin)
5) |oxymorphone
What |are |the |7 |synthetic |phenanthrenes? |- |CORRECT |ANSWER✔✔-1) |levorphanol
2) |butorphanol
3) |nalbuphine
4) |pentazocine
5) |naloxone
6) |naltrexone
7) |nalmefene
What |are |the |two |mixed |opioids? |(synthetic |phenanthrenes) |- |CORRECT |ANSWER✔✔-1) |
nalbuphine |- |can |antagonize |respiratory |depression |and |pruritus, |but |maintain |analgesia |
2) |butorphanol
,MU |antagonists, |Kappa |partial |agonists, |and |Delta |agonists
What |are |the |6 |piperidines? |(all |are |referred |to |as |phenylpiperidines |even |though |this |isn't |
technically |correct) |- |CORRECT |ANSWER✔✔-1) |meperidine |--> |HISTAMINE
2) |loperamide
3) |Fentanyl
4) |Sufentanil
5) |Alfentanil
6) |Remifentanil
What |is |the |only |diphenylheptane? |- |CORRECT |ANSWER✔✔-methadone
Which |are |the |3 |specific |drugs |that |are |MOST |likely |to |stimulate |histamine |release? |- |CORRECT
|ANSWER✔✔-1) |codeine
2) |morphine
3) |meperidine
-general |rule |= |phenanthrines |and |demerol
Are |there |cross |allergies |between |classes? |- |CORRECT |ANSWER✔✔-NO
-just |AMONG |classes
1) |If |someone |is |allergic |to |Vicodin |can |they |have |oxycodone?
2) |If |someone |is |allergic |to |morphine |can |they |have |dilaudid?
3) |If |someone |is |allergic |to |codeine |can |they |have |demerol?
4) |If |someone |is |allergic |to |fentanyl |can |they |have |morphine? |- |CORRECT |ANSWER✔✔-1) |NO
2) |NO
3) |YES
, 4) |YES
Why |do |opioids |cause |analgesia? |- |CORRECT |ANSWER✔✔--suppress |release |of |pain |chemicals |
-PRESYNAPTIC |AGONISTS |THAT |CAUSE |INHIBITION |OF |RELEASE |OF |SUBSTANCE |P |and |other |
neurotransmitters
What |class |includes |the |drugs |of |choice |for |asthmatics? |- |CORRECT |ANSWER✔✔--
phenylpiperidines |EXCEPT |demerol |
-ex: |FENTANYL |is |safe
Opioid |with |equal |potency |to |fentanyl |- |CORRECT |ANSWER✔✔-remifentanil
Opioid |with |weakest |potency |- |CORRECT |ANSWER✔✔-codeine
Opioid |with |strongest |potency |- |CORRECT |ANSWER✔✔-Sufentanil |(MU |agonist)
What |are |the |4 |endogenous |opioid |peptides? |- |CORRECT |ANSWER✔✔-1) |enkephalins
2) |B-endorphins
3) |Dynorphins |
4) |Endomorphins
What |is |the |MAIN |receptor |that |causes |analgesia? |- |CORRECT |ANSWER✔✔--MU
-if |all |do |the |action |write |MU |because |it |is |the |MAIN |one
What |endogenous |receptor |causes |dysphoria |AND |sedation? |- |CORRECT |ANSWER✔✔--Kappa |
-also |think |SHIVERING |for |kappa
Correct Answers
What |are |the |3 |naturally |occurring |phenanthrenes? |- |CORRECT |ANSWER✔✔-1) |Morphine |--> |
HISTAMINE
2) |Codeine |---> |HISTAMINE
3) |Thebaine
What |are |the |5 |semisynthetic |phenanthrenes? |- |CORRECT |ANSWER✔✔-1) |heroin
2) |vicodin |(Hydrocodone) |
3) |dialudid |(hydromorphone)
4) |oxycodone |(oxycontin)
5) |oxymorphone
What |are |the |7 |synthetic |phenanthrenes? |- |CORRECT |ANSWER✔✔-1) |levorphanol
2) |butorphanol
3) |nalbuphine
4) |pentazocine
5) |naloxone
6) |naltrexone
7) |nalmefene
What |are |the |two |mixed |opioids? |(synthetic |phenanthrenes) |- |CORRECT |ANSWER✔✔-1) |
nalbuphine |- |can |antagonize |respiratory |depression |and |pruritus, |but |maintain |analgesia |
2) |butorphanol
,MU |antagonists, |Kappa |partial |agonists, |and |Delta |agonists
What |are |the |6 |piperidines? |(all |are |referred |to |as |phenylpiperidines |even |though |this |isn't |
technically |correct) |- |CORRECT |ANSWER✔✔-1) |meperidine |--> |HISTAMINE
2) |loperamide
3) |Fentanyl
4) |Sufentanil
5) |Alfentanil
6) |Remifentanil
What |is |the |only |diphenylheptane? |- |CORRECT |ANSWER✔✔-methadone
Which |are |the |3 |specific |drugs |that |are |MOST |likely |to |stimulate |histamine |release? |- |CORRECT
|ANSWER✔✔-1) |codeine
2) |morphine
3) |meperidine
-general |rule |= |phenanthrines |and |demerol
Are |there |cross |allergies |between |classes? |- |CORRECT |ANSWER✔✔-NO
-just |AMONG |classes
1) |If |someone |is |allergic |to |Vicodin |can |they |have |oxycodone?
2) |If |someone |is |allergic |to |morphine |can |they |have |dilaudid?
3) |If |someone |is |allergic |to |codeine |can |they |have |demerol?
4) |If |someone |is |allergic |to |fentanyl |can |they |have |morphine? |- |CORRECT |ANSWER✔✔-1) |NO
2) |NO
3) |YES
, 4) |YES
Why |do |opioids |cause |analgesia? |- |CORRECT |ANSWER✔✔--suppress |release |of |pain |chemicals |
-PRESYNAPTIC |AGONISTS |THAT |CAUSE |INHIBITION |OF |RELEASE |OF |SUBSTANCE |P |and |other |
neurotransmitters
What |class |includes |the |drugs |of |choice |for |asthmatics? |- |CORRECT |ANSWER✔✔--
phenylpiperidines |EXCEPT |demerol |
-ex: |FENTANYL |is |safe
Opioid |with |equal |potency |to |fentanyl |- |CORRECT |ANSWER✔✔-remifentanil
Opioid |with |weakest |potency |- |CORRECT |ANSWER✔✔-codeine
Opioid |with |strongest |potency |- |CORRECT |ANSWER✔✔-Sufentanil |(MU |agonist)
What |are |the |4 |endogenous |opioid |peptides? |- |CORRECT |ANSWER✔✔-1) |enkephalins
2) |B-endorphins
3) |Dynorphins |
4) |Endomorphins
What |is |the |MAIN |receptor |that |causes |analgesia? |- |CORRECT |ANSWER✔✔--MU
-if |all |do |the |action |write |MU |because |it |is |the |MAIN |one
What |endogenous |receptor |causes |dysphoria |AND |sedation? |- |CORRECT |ANSWER✔✔--Kappa |
-also |think |SHIVERING |for |kappa
