2025 AQA GCSE COMBINED SCIENCE: TRILOGY 8464/B/2F
Foundation Tier Biology Paper 2F
Question Paper with Marking Scheme Attached
Please write clearly in block capitals.
Centre number Candidate number
Surname
Forename(s)
Candidate signature
I declare this is my own work.
GCSE
COMBINED SCIENCE: TRILOGY
Foundation Tier
F
Biology Paper 2F
Monday 9 June 2025 Morning Time allowed: 1 hour 15 minutes
Materials For Examiner’s Use
For this paper you must have:
• a ruler Question Mark
• a scientific calculator. 1
2
Instructions
• Use black ink or black ball-point pen. 3
• Pencil should only be used for drawing. 4
• Fill in the boxes at the top of this page. 5
• Answer all questions in the spaces provided.
6
• If you need extra space for your answer(s), use the lined pages at the end of
this book. Write the question number against your answer(s). TOTAL
• Do all rough work in this book. Cross through any work you do not want to be
marked.
• In all calculations, show clearly how you work out your answer.
Information
• The maximum mark for this paper is 70.
• The marks for questions are shown in brackets.
• You are expected to use a calculator where appropriate.
• You are reminded of the need for good English and clear presentation in your answers.
, 2
Do not write
outside the
0 1 The concentration of glucose in the blood can be controlled. box
0 1 . 1 A person drinks a glucose solution.
What happens to the person’s blood glucose concentration soon after drinking
the glucose solution?
[1 mark]
Tick (✓) one box.
Blood glucose concentration decreases.
Blood glucose concentration stays the same.
Blood glucose concentration increases.
0 1 . 2 Insulin controls blood glucose concentration.
Which organ produces insulin?
[1 mark]
Tick (✓) one box.
Pancreas
Pituitary
Stomach
IB/M/Jun25/8464/B/2F
, 3
Do not write
outside the
0 1 . 3 Organs affected by insulin are called target organs. box
Which two organs are target organs for insulin?
[2 marks]
Tick (✓) two boxes.
Liver
Lung
Muscle
Ovary
Spinal cord
0 1 . 4 Complete the sentences.
Choose answers from the box.
[2 marks]
DNA glucose glycogen urea
Insulin causes cells to take in .
The storage molecule made inside the cells is .
Question 1 continues on the next page
Turn over ►
IB/M/Jun25/8464/B/2F
, 4
Do not write
outside the
0 1 . 5 Complete the sentence. box
Choose the answer from the box.
[1 mark]
increase stay the same decrease
Insulin causes blood glucose concentration to .
0 1 . 6 Type 2 diabetes is caused when the body cells no longer respond to insulin.
Give two ways to reduce the risk of developing Type 2 diabetes.
Do not refer to insulin in your answer.
[2 marks]
1
2
9
IB/M/Jun25/8464/B/2F
Foundation Tier Biology Paper 2F
Question Paper with Marking Scheme Attached
Please write clearly in block capitals.
Centre number Candidate number
Surname
Forename(s)
Candidate signature
I declare this is my own work.
GCSE
COMBINED SCIENCE: TRILOGY
Foundation Tier
F
Biology Paper 2F
Monday 9 June 2025 Morning Time allowed: 1 hour 15 minutes
Materials For Examiner’s Use
For this paper you must have:
• a ruler Question Mark
• a scientific calculator. 1
2
Instructions
• Use black ink or black ball-point pen. 3
• Pencil should only be used for drawing. 4
• Fill in the boxes at the top of this page. 5
• Answer all questions in the spaces provided.
6
• If you need extra space for your answer(s), use the lined pages at the end of
this book. Write the question number against your answer(s). TOTAL
• Do all rough work in this book. Cross through any work you do not want to be
marked.
• In all calculations, show clearly how you work out your answer.
Information
• The maximum mark for this paper is 70.
• The marks for questions are shown in brackets.
• You are expected to use a calculator where appropriate.
• You are reminded of the need for good English and clear presentation in your answers.
, 2
Do not write
outside the
0 1 The concentration of glucose in the blood can be controlled. box
0 1 . 1 A person drinks a glucose solution.
What happens to the person’s blood glucose concentration soon after drinking
the glucose solution?
[1 mark]
Tick (✓) one box.
Blood glucose concentration decreases.
Blood glucose concentration stays the same.
Blood glucose concentration increases.
0 1 . 2 Insulin controls blood glucose concentration.
Which organ produces insulin?
[1 mark]
Tick (✓) one box.
Pancreas
Pituitary
Stomach
IB/M/Jun25/8464/B/2F
, 3
Do not write
outside the
0 1 . 3 Organs affected by insulin are called target organs. box
Which two organs are target organs for insulin?
[2 marks]
Tick (✓) two boxes.
Liver
Lung
Muscle
Ovary
Spinal cord
0 1 . 4 Complete the sentences.
Choose answers from the box.
[2 marks]
DNA glucose glycogen urea
Insulin causes cells to take in .
The storage molecule made inside the cells is .
Question 1 continues on the next page
Turn over ►
IB/M/Jun25/8464/B/2F
, 4
Do not write
outside the
0 1 . 5 Complete the sentence. box
Choose the answer from the box.
[1 mark]
increase stay the same decrease
Insulin causes blood glucose concentration to .
0 1 . 6 Type 2 diabetes is caused when the body cells no longer respond to insulin.
Give two ways to reduce the risk of developing Type 2 diabetes.
Do not refer to insulin in your answer.
[2 marks]
1
2
9
IB/M/Jun25/8464/B/2F
