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APHON CHEMO COURSE PRACTICE SCRIPT UPDATED 2026 TESTED SOLUTIONS

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APHON CHEMO COURSE PRACTICE SCRIPT UPDATED 2026 TESTED SOLUTIONS

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APHON CHEMO
Course
APHON CHEMO

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APHON CHEMO COURSE PRACTICE
SCRIPT UPDATED 2026 TESTED SOLUTIONS
⫸ Tyrosine kinase inhibitors (TKIs) are what class Answer: Biotherapy


⫸ Monoclonal antibodies (MoAbs) are what class Answer: Biotherapy


⫸ Define pharmacokinetics Answer: Study of drug absorption,
metabolism, and excretion


⫸ Define pharmacodynamics Answer: The concentration of the drug in
the body and how it produces a response


⫸ Define adjuvant chemotherapy Answer: The use of chemo after
another type of therapy, such as surgery, to treat residual disease or
undetectable metastasis.


⫸ Define neoadjuvant chemotherapy Answer: When chemo is used
preoperatively to decrease tumor burden in order to make it easier to
remove the tumor surgically.


⫸ Define sanctuary sites Answer: Sites within the body where tumor
cells sequester and are not easily reached by chemo such as the CNS


⫸ What normal cells are most often effected by chemotherapy Answer:
Hematopoietic, mucosal (mouth & GI), hair follicles

, ⫸ Why use chemotherapy Answer: To prevent cancer cells from
dividing, metastasizing, and ultimately causing the death of the patient


⫸ Cure Answer: To permanently eradicate the cancer


⫸ Control Answer: To extend the length & QOL when cure is not
feasible or realistic


⫸ Palliation Answer: Minimize pain and suffering during end of life


⫸ Resting phase of cell cycle Answer: Gap 0 - cells not dividing


⫸ Postmitotic phase Answer: Gap 1 - enzymes needed for DNA
synthesis are produced, protein and RNA synthesis takes place (18
Hours)


⫸ Synthesis (S) Phase Answer: Cellular DNA duplicated (20 hours)


⫸ Premitotic phase Answer: Gap 2 - both protein and RNA synthesis
occur, precursors of mitotic spindle are produced. Shortest phase


⫸ Mitosis (M) Phase Answer: Cell division occurs in 4-step phase
(prophase, metaphase, anaphase, telophase) 1 Hour

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