APEA Orthopedics Pharmacology | Latest 2025 Revised Questions & Correct Answers Verified

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APEA- ORTHOPEDICS PHARM LATEST 2025
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increasing the urinary excretion of uric acid and inhibiting the secretion of
penicillin.
Probenecid, used in the treatment of gout, works by:
-decreasing the tubular secretion of uric acid and inhibiting the secretion of
penicillin.
-destroying uric acid crystals in the renal tubular system and slowing the
metabolism of penicillin.
-increasing the urinary excretion of uric acid and inhibiting the secretion of
penicillin.
-promoting the bactericidal activity of penicillin and breaking down uric acid.




Liver function test
Before prescribing Dantrolene (Dantrium), a peripherally-acting muscle relaxant,
obtain a baseline serum:
blood urea nitrogen (BUN).




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complete blood count (CBC).
calcium level.
liver function test.




acute gout exacerbation
Which of the following is NOT a reason to discontinue allopurinol (Zyloprim)?
Acute gout exacerbation
Dysuria
Jaundice
Skin rash




consistently fasting or nonfasting.


do not switch method of administrations- will change absorption of drug
Patients should be instructed to take tizanidine (Zanaflex):
daily, not exceeding 16 mg daily.
before bedtime only.
with food only.
consistently fasting or nonfasting.




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4 grams
The maximum recommended daily dose of acetaminophen (Tylenol) for the
management of pain associated with a clavicular fracture is:
1 gram.
2 grams.
3 grams.
4 grams.




seizures
Patients should be instructed to avoid abrupt withdrawal of baclofen (Lioresal) to
prevent the occurrence of:
hypotonia.
urinary retention.
seizures.
hypothermia.




indicated for short-term treatment of moderate pain.
Ketorolac (Toradol), a nonsteroidal anti-inflammatory drug, is:
indicated for short-term treatment of moderate pain.




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not known to cause renal insufficiency.
indicated for the treatment of moderate pain in children.
indicated for pain following coronary artery bypass graft surgery.




gastrointestinal bleeding


Patients may develop increased gastrointestinal symptoms and bleeding because
both products diminish the gastroprotective effects of prostaglandins.
When corticosteroids are used in combination with nonsteroidal anti-
inflammatory drugs (NSAIDs), patients may develop:
osteoarthritis.
diabetes insipidus.
gastrointestinal bleeding.
hypoglycemia.




tramadol (Ultram)
Which of the following is NOT classified as a muscle relaxant:
metaxalone (Skelaxin).
cyclobenzaprine (Amrix).
methocarbamol (Robaxin).
tramadol (Ultram).




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