SBB Human Blood Groups Exam
QUESTIONS AND ANSWERS 100%
RATED CORRECT WITH 100% SURE
PASS|GRADED A+
How would Ulex europaeus react with O, A, A2, B, A2B, A1B RBCs? - CORRECT ANSWERS
O>A2>B>A2B>A1>A1B
How could you distinguish serologically A1, A2 and A3 - CORRECT ANSWERS Dolichos
biflorus can will react with A1 and not A2. A3 yields mixed field reactions with anti-A and anti-A,B
What is the correct order of type of RBCs to transfuse in an AB patient when AB RBCs are not available?
Why? - CORRECT ANSWERS A, B, O; the residual anti-B in A RBCs is less immunogenic than
the residual anti-A in B RBCs
What type of RBCs would you transfuse to a patient with anti-G - CORRECT ANSWERS RBCs
transfused must lack the D and C antigens
Can you detect a weak D using Gel Technology? - CORRECT ANSWERS No, because there is
no washing phase
Can an Rh positive father and Rh positive mother yield an Rh negative child - CORRECT ANSWERS
Yes, if both parents are heterozygous for the D gene. Inheritance is autosomal recessive
What type of RBCs in regards to Rh phenotype would you transfuse in a patient with anti-f - CORRECT
ANSWERS RBCs should be negative for the c and e antigens
,How could you solve an ABO discrepancy where Anti-M was causing aberrant results in reverse grouping
when the forward type is consistent with A blood group and reverse as O? - CORRECT ANSWERS
Treat A1 cells with ficin to denature the M antigen, repeat reverse grouping with ficin-treated A1 cells.
Why do you see an anti-N like specificity in dialysis patients? - CORRECT ANSWERS
Formaldehyde induced antibody to 'N' due to formaldehyde used in dialysis procedures.
A patient types as follows: anti-A=4+, Anti-B=1+, A1 Cells=2+, B cells=4+. The ABO discrepancy led to
suspicion of a possible cold autoantibody based on patient histopry and diagnosis. RESt was used in an
attept to adsorb the autoantobidy. The type was repeated with adsorbed plasma Anit-A=4+, Anti-B=0,
A1 cells=0, B cells=0. What could be the cause of this discrepancy? - CORRECT ANSWERS
Anti-B was adsorbed out with RESt.
What enzyme may be useful in distinguishing anti-Ge2? - CORRECT ANSWERS papain
The beta 1-3 linkage between galactose and N-acetylglucosamine is found in? - CORRECT ANSWERS
secretions
Represents Type II chain - CORRECT ANSWERS Beta 1-4 linkage between galactose and N
acetyl glucosamine
Represents decreasing concentrations of H antigen on RBCs - CORRECT ANSWERS
O>A2>B>A2B>A1>A1B
The ABO genes are located on what chromosome - CORRECT ANSWERS Chromosome 9
Which glycosyltransferase is needed before A and B antigens are formed? - CORRECT ANSWERS
L-fucosyltransferase
, Which reflects the A3 subgroup - CORRECT ANSWERS mixed field reactions with Anti-A and
Anti-A,B.
Which fo the following reflects the A el subgroup? - CORRECT ANSWERS Positive reactions
with Anti-H
What clinical condition may yield positive reactions with Anti-A, negative with Anti-B, negative with A1
and B cells. - CORRECT ANSWERS hypogammaglobulinemia
What differentiates a Bombay anti-H from an anti-H cold agglutinin? - CORRECT ANSWERS
reactivity at body temperature.
This antigen is associated with linear carbohydrate chains - CORRECT ANSWERS i antigen
The following reactions are found on a 35-year old male. Anti-A=4+, Anti-B=0, Anti-A,B=4+, A1 cells=3+,
B cells=4+, O cells=3+. How could these results be explained? - CORRECT ANSWERS Anti-M
in plasma
Anti-IH would react best with which red blood cells? - CORRECT ANSWERS O RBCs
The acquired B phenomenon is only found in what ABO group? - CORRECT ANSWERS A
blood group
A2 subgroup - CORRECT ANSWERS Anti-A1 does not react. 1-8% of persons will produce
Anti-A1
Anti-Lu3 is associated with - CORRECT ANSWERS Recessive type Lu(a-b-)
The dominant Lu(a-b-) type is associated with what gene? - CORRECT ANSWERS In(Lu)
QUESTIONS AND ANSWERS 100%
RATED CORRECT WITH 100% SURE
PASS|GRADED A+
How would Ulex europaeus react with O, A, A2, B, A2B, A1B RBCs? - CORRECT ANSWERS
O>A2>B>A2B>A1>A1B
How could you distinguish serologically A1, A2 and A3 - CORRECT ANSWERS Dolichos
biflorus can will react with A1 and not A2. A3 yields mixed field reactions with anti-A and anti-A,B
What is the correct order of type of RBCs to transfuse in an AB patient when AB RBCs are not available?
Why? - CORRECT ANSWERS A, B, O; the residual anti-B in A RBCs is less immunogenic than
the residual anti-A in B RBCs
What type of RBCs would you transfuse to a patient with anti-G - CORRECT ANSWERS RBCs
transfused must lack the D and C antigens
Can you detect a weak D using Gel Technology? - CORRECT ANSWERS No, because there is
no washing phase
Can an Rh positive father and Rh positive mother yield an Rh negative child - CORRECT ANSWERS
Yes, if both parents are heterozygous for the D gene. Inheritance is autosomal recessive
What type of RBCs in regards to Rh phenotype would you transfuse in a patient with anti-f - CORRECT
ANSWERS RBCs should be negative for the c and e antigens
,How could you solve an ABO discrepancy where Anti-M was causing aberrant results in reverse grouping
when the forward type is consistent with A blood group and reverse as O? - CORRECT ANSWERS
Treat A1 cells with ficin to denature the M antigen, repeat reverse grouping with ficin-treated A1 cells.
Why do you see an anti-N like specificity in dialysis patients? - CORRECT ANSWERS
Formaldehyde induced antibody to 'N' due to formaldehyde used in dialysis procedures.
A patient types as follows: anti-A=4+, Anti-B=1+, A1 Cells=2+, B cells=4+. The ABO discrepancy led to
suspicion of a possible cold autoantibody based on patient histopry and diagnosis. RESt was used in an
attept to adsorb the autoantobidy. The type was repeated with adsorbed plasma Anit-A=4+, Anti-B=0,
A1 cells=0, B cells=0. What could be the cause of this discrepancy? - CORRECT ANSWERS
Anti-B was adsorbed out with RESt.
What enzyme may be useful in distinguishing anti-Ge2? - CORRECT ANSWERS papain
The beta 1-3 linkage between galactose and N-acetylglucosamine is found in? - CORRECT ANSWERS
secretions
Represents Type II chain - CORRECT ANSWERS Beta 1-4 linkage between galactose and N
acetyl glucosamine
Represents decreasing concentrations of H antigen on RBCs - CORRECT ANSWERS
O>A2>B>A2B>A1>A1B
The ABO genes are located on what chromosome - CORRECT ANSWERS Chromosome 9
Which glycosyltransferase is needed before A and B antigens are formed? - CORRECT ANSWERS
L-fucosyltransferase
, Which reflects the A3 subgroup - CORRECT ANSWERS mixed field reactions with Anti-A and
Anti-A,B.
Which fo the following reflects the A el subgroup? - CORRECT ANSWERS Positive reactions
with Anti-H
What clinical condition may yield positive reactions with Anti-A, negative with Anti-B, negative with A1
and B cells. - CORRECT ANSWERS hypogammaglobulinemia
What differentiates a Bombay anti-H from an anti-H cold agglutinin? - CORRECT ANSWERS
reactivity at body temperature.
This antigen is associated with linear carbohydrate chains - CORRECT ANSWERS i antigen
The following reactions are found on a 35-year old male. Anti-A=4+, Anti-B=0, Anti-A,B=4+, A1 cells=3+,
B cells=4+, O cells=3+. How could these results be explained? - CORRECT ANSWERS Anti-M
in plasma
Anti-IH would react best with which red blood cells? - CORRECT ANSWERS O RBCs
The acquired B phenomenon is only found in what ABO group? - CORRECT ANSWERS A
blood group
A2 subgroup - CORRECT ANSWERS Anti-A1 does not react. 1-8% of persons will produce
Anti-A1
Anti-Lu3 is associated with - CORRECT ANSWERS Recessive type Lu(a-b-)
The dominant Lu(a-b-) type is associated with what gene? - CORRECT ANSWERS In(Lu)
