MEDICAL SCIENCES UAMS COMPREHENSIVE
EXAM 2026 QUESTIONS WITH SOLUTIONS
GRADED A+
◉ What is the normal size of a RBC. Answer: about the same size as
the nucleus of a lymphocyte
◉ Schistocytes image. Answer:
◉ Dacrocyte image. Answer: tear drop
◉ What is a Dacrocyte. Answer: Round cell with a single elongated
or pointed extremity
◉ What defect is with Ovalocytes?. Answer: Defect in Spectrin
(protein in RBC membrane)
◉ Why will we observe approximate 1% of RBCs as
polychromatophilic?. Answer: Due to the 1% released daily from BM
◉ What is an Ovalocyte?. Answer: Rod or oval shaped
,Oval shape increases as cell matures
Hereditary or acquired conditions
◉ spherocytes image. Answer:
◉ In what conditions do you see Ovalocytes?. Answer: Hereditary
ovalocytosis - if majority are oval
Sickle cell anemia
Iron deficiency anemia
RBC enzyme deficiencies
Pernicious anemia as macro-ovalocytes
Miscellaneous anemia - non-specific
◉ Codocytes image. Answer:
◉ Stomatocytes image. Answer:
◉ What does Hemoglobin S do?. Answer: Decreased solubility
Homozygous causes severe hemolytic anemia
Sickling occurs when oxygen tension decreases
Heterozygous have both normal and abnormal hemoglobin
, ◉ Howell-Jolly Bodies image. Answer:
◉ Basophilic Stippling Image. Answer:
◉ What is an Acanthocyte?. Answer: Membranes have altered lipid
content
Increased cholesterol
Have a normal life span
Slightly decreased osmotic fragility
◉ Siderocytes Image. Answer:
◉ What conditions would you see Acanthocytes?. Answer: Liver
disease
Congenital Abetaproteinemia - rare
Alcoholic liver disease
Post splenectomy
◉ What is a Siderocyte?. Answer: Pappenheimer Bodies
Collection of mitochondria and ribosomes that contain iron
EXAM 2026 QUESTIONS WITH SOLUTIONS
GRADED A+
◉ What is the normal size of a RBC. Answer: about the same size as
the nucleus of a lymphocyte
◉ Schistocytes image. Answer:
◉ Dacrocyte image. Answer: tear drop
◉ What is a Dacrocyte. Answer: Round cell with a single elongated
or pointed extremity
◉ What defect is with Ovalocytes?. Answer: Defect in Spectrin
(protein in RBC membrane)
◉ Why will we observe approximate 1% of RBCs as
polychromatophilic?. Answer: Due to the 1% released daily from BM
◉ What is an Ovalocyte?. Answer: Rod or oval shaped
,Oval shape increases as cell matures
Hereditary or acquired conditions
◉ spherocytes image. Answer:
◉ In what conditions do you see Ovalocytes?. Answer: Hereditary
ovalocytosis - if majority are oval
Sickle cell anemia
Iron deficiency anemia
RBC enzyme deficiencies
Pernicious anemia as macro-ovalocytes
Miscellaneous anemia - non-specific
◉ Codocytes image. Answer:
◉ Stomatocytes image. Answer:
◉ What does Hemoglobin S do?. Answer: Decreased solubility
Homozygous causes severe hemolytic anemia
Sickling occurs when oxygen tension decreases
Heterozygous have both normal and abnormal hemoglobin
, ◉ Howell-Jolly Bodies image. Answer:
◉ Basophilic Stippling Image. Answer:
◉ What is an Acanthocyte?. Answer: Membranes have altered lipid
content
Increased cholesterol
Have a normal life span
Slightly decreased osmotic fragility
◉ Siderocytes Image. Answer:
◉ What conditions would you see Acanthocytes?. Answer: Liver
disease
Congenital Abetaproteinemia - rare
Alcoholic liver disease
Post splenectomy
◉ What is a Siderocyte?. Answer: Pappenheimer Bodies
Collection of mitochondria and ribosomes that contain iron
