CLINICAL IMMUNOLOGY AND SEROLOGY
TEST BANK 2026 COMPLETE QUESTIONS AND
VERIFIED SOLUTIONS GRADED A+
◉ Type I reactions. Answer: immediate-type hypersensitivities
can range from mild food allergies to anaphylatic shock
can be systemic, but most are localized
◉ Type I reactions. Answer: antigens complex with IgE and attach to
basophils or tissue mast cells, which results in the release of
histamines and the synthesis of leukotrienes
◉ Type I reactions. Answer: urticaria (hives)
hay fever
bronchial asthma
food allergies
◉ Type II reactions. Answer: cytotoxic responses
,complement-fixing IgG or IgM antibodies are directed against
cellular or tissue antigens such as those found on the surface of
WBCs and platelets
◉ Type II reactions. Answer: HTR
HDN
immune thrombocytopenia
certain drug allergies
◉ Type III reactions. Answer: immune complex reactions
IgG and IgM antibodies form soluble immune complexes with
antigens
these complexes may be deposited in extravascular tissues, which
results in infiltration by neuts and local tissue damage
complement is also activated and contributes to the inflammatory
response
◉ Type III reactions. Answer: immune glomerulonephritis
serum sickness
arthus reactions
, ◉ Type IV reactions. Answer: delayed-type hypersensitivity
reactions
CD4+ T cells react with the foreign antigen and release lymphokines,
some of which are chemoattractants that attract PMNs, monocytes,
and macrophages
these cells release substances such as proteases, collagenases,
cathepsins, and TNS, which mediate inflammation
◉ Type IV reactions. Answer: Tuberculin skin test
contact dermatitis
◉ autoimmunity. Answer: an expression of the Ir that occurs when
the body's self-tolerance system fails
the body's immune cells are no longer able to recognize "self' and
thus mount an Ir against its own antigens
◉ autoimmune diseases. Answer: all involve immune complexes
strongly influenced by MHC antigens and can involve either Class I
or Class II MHC proteins
TEST BANK 2026 COMPLETE QUESTIONS AND
VERIFIED SOLUTIONS GRADED A+
◉ Type I reactions. Answer: immediate-type hypersensitivities
can range from mild food allergies to anaphylatic shock
can be systemic, but most are localized
◉ Type I reactions. Answer: antigens complex with IgE and attach to
basophils or tissue mast cells, which results in the release of
histamines and the synthesis of leukotrienes
◉ Type I reactions. Answer: urticaria (hives)
hay fever
bronchial asthma
food allergies
◉ Type II reactions. Answer: cytotoxic responses
,complement-fixing IgG or IgM antibodies are directed against
cellular or tissue antigens such as those found on the surface of
WBCs and platelets
◉ Type II reactions. Answer: HTR
HDN
immune thrombocytopenia
certain drug allergies
◉ Type III reactions. Answer: immune complex reactions
IgG and IgM antibodies form soluble immune complexes with
antigens
these complexes may be deposited in extravascular tissues, which
results in infiltration by neuts and local tissue damage
complement is also activated and contributes to the inflammatory
response
◉ Type III reactions. Answer: immune glomerulonephritis
serum sickness
arthus reactions
, ◉ Type IV reactions. Answer: delayed-type hypersensitivity
reactions
CD4+ T cells react with the foreign antigen and release lymphokines,
some of which are chemoattractants that attract PMNs, monocytes,
and macrophages
these cells release substances such as proteases, collagenases,
cathepsins, and TNS, which mediate inflammation
◉ Type IV reactions. Answer: Tuberculin skin test
contact dermatitis
◉ autoimmunity. Answer: an expression of the Ir that occurs when
the body's self-tolerance system fails
the body's immune cells are no longer able to recognize "self' and
thus mount an Ir against its own antigens
◉ autoimmune diseases. Answer: all involve immune complexes
strongly influenced by MHC antigens and can involve either Class I
or Class II MHC proteins
