FAMILY MEDICINE COMAT LATEST QUESTIONS AND ACCURATE
ANSWERS FOR GUARANTEED RESULTS
1. Q: At what age should colorectal cancer screening begin in average-risk
patients? ANSWER Age 45 (updated from 50 in recent guidelines)
2. Q: What is the recommended screening interval for cervical cancer in
women aged 30-65? ANSWER Cytology plus HPV testing every 5 years, or
cytology alone every 3 years
3. Q: When should mammography screening begin for average-risk
women? ANSWER Age 40-50 (shared decision-making), definitely by 50,
continuing biennially until age 74
4. Q: What is the USPSTF recommendation for lung cancer screening?
ANSWER Annual low-dose CT for ages 50-80 with 20 pack-year history who
currently smoke or quit within 15 years
5. Q: At what age should lipid screening begin in men without risk factors?
ANSWER Age 35 (age 20 if risk factors present)
6. Q: What is the recommended screening test for abdominal aortic
aneurysm? ANSWER One-time ultrasound for men aged 65-75 who have ever
smoked
7. Q: When should osteoporosis screening begin in women? ANSWER Age
65, or younger postmenopausal women with increased fracture risk
8. Q: What is the recommended screening tool for depression in primary
care? ANSWER PHQ-9 (Patient Health Questionnaire-9)
9. Q: At what interval should blood pressure be checked in healthy adults?
ANSWER Annually for those with BP 120-129/<80; every 3-5 years if <120/80
10. Q: What is the recommended screening test for hepatitis C? ANSWER
One-time screening for all adults aged 18-79
Cardiovascular Disease
,11. Q: What is first-line treatment for hypertension in a Black patient
without diabetes? ANSWER Thiazide diuretic or calcium channel blocker
12. Q: What blood pressure goal is recommended for most adults with
hypertension? ANSWER <130/80 mmHg
13. Q: What is the first-line medication for stable angina? ANSWER Beta-
blocker
14. Q: Which statin intensity is recommended for secondary prevention of
ASCVD? ANSWER High-intensity statin (atorvastatin 40-80 mg or
rosuvastatin 20-40 mg)
15. Q: What is the target LDL for patients with established ASCVD?
ANSWER <70 mg/dL
16. Q: What physical exam finding is most specific for aortic regurgitation?
ANSWER Diastolic decrescendo murmur at left sternal border
17. Q: What is first-line treatment for acute atrial fibrillation with RVR in
a stable patient? ANSWER Rate control with beta-blocker or calcium channel
blocker
18. Q: What CHA2DS2-VASc score warrants anticoagulation in atrial
fibrillation? ANSWER ≥2 in men, ≥3 in women
19. Q: What is the most common cause of heart failure with preserved
ejection fraction? ANSWER Hypertension
20. Q: What medication reduces mortality in heart failure with reduced
ejection fraction? ANSWER ACE inhibitors, beta-blockers, aldosterone
antagonists, ARNI (sacubitril/valsartan)
Pulmonary Medicine
21. Q: What is the most common cause of community-acquired
pneumonia? ANSWER Streptococcus pneumoniae
22. Q: What are the CURB-65 criteria for pneumonia severity? ANSWER
Confusion, Uremia (BUN >20), Respiratory rate ≥30, BP <90/60, age ≥65
23. Q: What is first-line outpatient treatment for CAP in a healthy patient?
ANSWER Amoxicillin 1g TID or doxycycline
24. Q: What spirometry finding confirms COPD? ANSWER Post-
bronchodilator FEV1/FVC <0.70
, 25. Q: What is first-line maintenance therapy for COPD? ANSWER Long-
acting bronchodilator (LABA or LAMA)
26. Q: What defines severe persistent asthma? ANSWER Symptoms
throughout day, nighttime symptoms ≥7x/week, FEV1 <60% predicted
27. Q: What is the stepwise approach for mild persistent asthma?
ANSWER Low-dose inhaled corticosteroid
28. Q: What finding on chest X-ray is classic for sarcoidosis? ANSWER
Bilateral hilar lymphadenopathy
29. Q: What is the most sensitive test for pulmonary embolism? ANSWER
CT pulmonary angiography (CTPA)
30. Q: What is the Well's score used for? ANSWER Risk stratification for
pulmonary embolism and deep vein thrombosis
Endocrinology
31. Q: What HbA1c level confirms diabetes mellitus? ANSWER ≥6.5%
32. Q: What is the first-line medication for type 2 diabetes? ANSWER
Metformin
33. Q: What is the target HbA1c for most diabetic patients? ANSWER
<7%
34. Q: What diabetic medication causes weight loss and reduces
cardiovascular events? ANSWER GLP-1 receptor agonists and SGLT-2
inhibitors
35. Q: What is the Somogyi effect? ANSWER Morning hyperglycemia due to
nocturnal hypoglycemia causing counter-regulatory hormone release
36. Q: What is the dawn phenomenon? ANSWER Morning hyperglycemia
due to increased growth hormone and cortisol release in early morning
37. Q: What lab finding is most specific for primary hypothyroidism?
ANSWER Elevated TSH with low free T4
38. Q: What is first-line treatment for hypothyroidism? ANSWER
Levothyroxine
39. Q: What is the most common cause of hyperthyroidism? ANSWER
Graves disease
ANSWERS FOR GUARANTEED RESULTS
1. Q: At what age should colorectal cancer screening begin in average-risk
patients? ANSWER Age 45 (updated from 50 in recent guidelines)
2. Q: What is the recommended screening interval for cervical cancer in
women aged 30-65? ANSWER Cytology plus HPV testing every 5 years, or
cytology alone every 3 years
3. Q: When should mammography screening begin for average-risk
women? ANSWER Age 40-50 (shared decision-making), definitely by 50,
continuing biennially until age 74
4. Q: What is the USPSTF recommendation for lung cancer screening?
ANSWER Annual low-dose CT for ages 50-80 with 20 pack-year history who
currently smoke or quit within 15 years
5. Q: At what age should lipid screening begin in men without risk factors?
ANSWER Age 35 (age 20 if risk factors present)
6. Q: What is the recommended screening test for abdominal aortic
aneurysm? ANSWER One-time ultrasound for men aged 65-75 who have ever
smoked
7. Q: When should osteoporosis screening begin in women? ANSWER Age
65, or younger postmenopausal women with increased fracture risk
8. Q: What is the recommended screening tool for depression in primary
care? ANSWER PHQ-9 (Patient Health Questionnaire-9)
9. Q: At what interval should blood pressure be checked in healthy adults?
ANSWER Annually for those with BP 120-129/<80; every 3-5 years if <120/80
10. Q: What is the recommended screening test for hepatitis C? ANSWER
One-time screening for all adults aged 18-79
Cardiovascular Disease
,11. Q: What is first-line treatment for hypertension in a Black patient
without diabetes? ANSWER Thiazide diuretic or calcium channel blocker
12. Q: What blood pressure goal is recommended for most adults with
hypertension? ANSWER <130/80 mmHg
13. Q: What is the first-line medication for stable angina? ANSWER Beta-
blocker
14. Q: Which statin intensity is recommended for secondary prevention of
ASCVD? ANSWER High-intensity statin (atorvastatin 40-80 mg or
rosuvastatin 20-40 mg)
15. Q: What is the target LDL for patients with established ASCVD?
ANSWER <70 mg/dL
16. Q: What physical exam finding is most specific for aortic regurgitation?
ANSWER Diastolic decrescendo murmur at left sternal border
17. Q: What is first-line treatment for acute atrial fibrillation with RVR in
a stable patient? ANSWER Rate control with beta-blocker or calcium channel
blocker
18. Q: What CHA2DS2-VASc score warrants anticoagulation in atrial
fibrillation? ANSWER ≥2 in men, ≥3 in women
19. Q: What is the most common cause of heart failure with preserved
ejection fraction? ANSWER Hypertension
20. Q: What medication reduces mortality in heart failure with reduced
ejection fraction? ANSWER ACE inhibitors, beta-blockers, aldosterone
antagonists, ARNI (sacubitril/valsartan)
Pulmonary Medicine
21. Q: What is the most common cause of community-acquired
pneumonia? ANSWER Streptococcus pneumoniae
22. Q: What are the CURB-65 criteria for pneumonia severity? ANSWER
Confusion, Uremia (BUN >20), Respiratory rate ≥30, BP <90/60, age ≥65
23. Q: What is first-line outpatient treatment for CAP in a healthy patient?
ANSWER Amoxicillin 1g TID or doxycycline
24. Q: What spirometry finding confirms COPD? ANSWER Post-
bronchodilator FEV1/FVC <0.70
, 25. Q: What is first-line maintenance therapy for COPD? ANSWER Long-
acting bronchodilator (LABA or LAMA)
26. Q: What defines severe persistent asthma? ANSWER Symptoms
throughout day, nighttime symptoms ≥7x/week, FEV1 <60% predicted
27. Q: What is the stepwise approach for mild persistent asthma?
ANSWER Low-dose inhaled corticosteroid
28. Q: What finding on chest X-ray is classic for sarcoidosis? ANSWER
Bilateral hilar lymphadenopathy
29. Q: What is the most sensitive test for pulmonary embolism? ANSWER
CT pulmonary angiography (CTPA)
30. Q: What is the Well's score used for? ANSWER Risk stratification for
pulmonary embolism and deep vein thrombosis
Endocrinology
31. Q: What HbA1c level confirms diabetes mellitus? ANSWER ≥6.5%
32. Q: What is the first-line medication for type 2 diabetes? ANSWER
Metformin
33. Q: What is the target HbA1c for most diabetic patients? ANSWER
<7%
34. Q: What diabetic medication causes weight loss and reduces
cardiovascular events? ANSWER GLP-1 receptor agonists and SGLT-2
inhibitors
35. Q: What is the Somogyi effect? ANSWER Morning hyperglycemia due to
nocturnal hypoglycemia causing counter-regulatory hormone release
36. Q: What is the dawn phenomenon? ANSWER Morning hyperglycemia
due to increased growth hormone and cortisol release in early morning
37. Q: What lab finding is most specific for primary hypothyroidism?
ANSWER Elevated TSH with low free T4
38. Q: What is first-line treatment for hypothyroidism? ANSWER
Levothyroxine
39. Q: What is the most common cause of hyperthyroidism? ANSWER
Graves disease
