NUR 545 Final Exam With 100 %
Cottect Answers
Drug interaction for penicillin? - o Aminoglycosides- don't mix penicillin with
this drug. Penicillin deactivates aminoglycoside.
MOA for penicillin? - o disrupts bacterial cells wall which leads to cell death
Adverse effect of penicillin? - o anaphylactic reaction (s/s: SOB, rash,
angioedema). Give epinephrine when this occurs.
High-risk patients for penicillin - o The elderly or renal impairment (reduce
the dose)
What's the cross-reactivity with penicillin (beta lactam ring)? - o
Cephalosporins- a small percentage of people who get a reaction with
penicillin will have a reaction when taking cephalosporins.
High risk population for gentamicin? - patients w/renal impairment
Major adverse effects of gentamicin? - Ototoxicity, nephrotoxicity.
gentamicin s/s of ototoxicity (HHTNV)? - -tinnitus, hearing loss, vertigo,
headache, nausea. (HHTNV)
Gentamicin- first sign of ototoxicity? - h/a
What's the neuromuscular blockade reversal agent for gentamicin? - IV
calcium gluconate.
Therapeutic use for Fosfomycin? - UTI-single dose
Drug interaction for Cefotetan? - o ALCOHOL causes disulfiram reaction
(flushing, palpitation, nausea).
, Adverse effect of Vancomycin? - Red Man Syndrome, red from the torso
up, V/S- hypotension, tachycardia. This occurs when an infusion is given
too quickly.
First-line drug use for tetracycline? - o Rickettsia disease, Chlamydia,
Lyme disease.
Adverse effects of tetracycline? - -Long bone suppression- suppresses
growth in premature infants
-teeth discoloration (for children under the age of eight)
-fetal harm in pregnant women & breast-feeding women (they must avoid
this drug)
Food interaction with tetracycline? - milk products suppress absorption
Adverse effect of trimethoprim/sulfamethoxazole (Bactrim)? - o
Kernicterus in neonates- elevated bilirubin which can lead to cerebral
palsy, hearing loss, and effect the teeth.
For a patient taking trimethoprim/sulfamethoxazole (Bactrim), what
statement indicates that symptoms are not improving? - I'm having flank
pain.
Major adverse effects for fluroquinolones (ciprofloxacin & levofloxacin)? - o
Tendon rupture/tendonitis (patient will complain of heel pain), &
phototoxicity (sunscreen, wear long sleeves, avoid prolonged exposure to
the sun)
Major adverse effect of Macrolide (erythromycin)? - o QT prolongation
which can lead to cardiac death.
Drug use for Acyclovir? - o HSV
Acyclovir- therapeutic goal for treating herpes? - o If a patient is having an
active episode, the goal is to reduce lesions.
Is Acyclovir a teratogenic? - o No, it's safe to use during pregnancy.
Cottect Answers
Drug interaction for penicillin? - o Aminoglycosides- don't mix penicillin with
this drug. Penicillin deactivates aminoglycoside.
MOA for penicillin? - o disrupts bacterial cells wall which leads to cell death
Adverse effect of penicillin? - o anaphylactic reaction (s/s: SOB, rash,
angioedema). Give epinephrine when this occurs.
High-risk patients for penicillin - o The elderly or renal impairment (reduce
the dose)
What's the cross-reactivity with penicillin (beta lactam ring)? - o
Cephalosporins- a small percentage of people who get a reaction with
penicillin will have a reaction when taking cephalosporins.
High risk population for gentamicin? - patients w/renal impairment
Major adverse effects of gentamicin? - Ototoxicity, nephrotoxicity.
gentamicin s/s of ototoxicity (HHTNV)? - -tinnitus, hearing loss, vertigo,
headache, nausea. (HHTNV)
Gentamicin- first sign of ototoxicity? - h/a
What's the neuromuscular blockade reversal agent for gentamicin? - IV
calcium gluconate.
Therapeutic use for Fosfomycin? - UTI-single dose
Drug interaction for Cefotetan? - o ALCOHOL causes disulfiram reaction
(flushing, palpitation, nausea).
, Adverse effect of Vancomycin? - Red Man Syndrome, red from the torso
up, V/S- hypotension, tachycardia. This occurs when an infusion is given
too quickly.
First-line drug use for tetracycline? - o Rickettsia disease, Chlamydia,
Lyme disease.
Adverse effects of tetracycline? - -Long bone suppression- suppresses
growth in premature infants
-teeth discoloration (for children under the age of eight)
-fetal harm in pregnant women & breast-feeding women (they must avoid
this drug)
Food interaction with tetracycline? - milk products suppress absorption
Adverse effect of trimethoprim/sulfamethoxazole (Bactrim)? - o
Kernicterus in neonates- elevated bilirubin which can lead to cerebral
palsy, hearing loss, and effect the teeth.
For a patient taking trimethoprim/sulfamethoxazole (Bactrim), what
statement indicates that symptoms are not improving? - I'm having flank
pain.
Major adverse effects for fluroquinolones (ciprofloxacin & levofloxacin)? - o
Tendon rupture/tendonitis (patient will complain of heel pain), &
phototoxicity (sunscreen, wear long sleeves, avoid prolonged exposure to
the sun)
Major adverse effect of Macrolide (erythromycin)? - o QT prolongation
which can lead to cardiac death.
Drug use for Acyclovir? - o HSV
Acyclovir- therapeutic goal for treating herpes? - o If a patient is having an
active episode, the goal is to reduce lesions.
Is Acyclovir a teratogenic? - o No, it's safe to use during pregnancy.
