PCB 3233 -EXAM 4 QUESTIONS AND ANSWERS

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PCB 3233 -EXAM 4 QUESTIONS AND ANSWERS

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2025/2026

Institution PCB 3233 Immunology

Course PCB 3233 Immunology

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PCB 3233 EXAM 4 STUDY GUID1.

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PCB 3233 -EXAM 4 QUESTIONS AND
ANSWERS

tgf-B0and0Il-170-0ans✔Regulatory0T0cells0secrete0which0of0the0following0cytokines?

True0-0ans✔Sphingosine01-phosphate0directs0naive0T-
cells0into0the0lymph0node0to0the0T-cell0arca.

Notch-1:0stimulate0-0ans✔Activated0T-cells0express0CTLA-
40which0binds0to0________0dendritic0cells0with0very0high0affinity0and0works0to0______
____activation0and0proliferation.

True0-0ans✔Formation0of0the0pre-
TCR0induces0proliferation0of0thymocytes,0during0which0the0expression0of0RAG-
10and0RAG-20is0maintained.

True0-
0ans✔AIRE0(autolmmune0regulator)0is0used0by0a0subpopulation0of0thymic0epithelial0ce
lls0during0positive0selection0to0produce0peripheral0self0peptides

After0they0are0done0maturing0-
0ans✔When0would0you0expect0T0cells0to0begin0exyessing0CD40and0CDB0on
their0surface?

Gamma0chains0and0delta0chains0-0ans✔Double-
negative0thymocytes0will0simultaneously0initiate0rearrangement0of0which0receptor0gene
s0first?

Macrophages0-
0ans✔All0of0the0following0are0professional0antigen0presenting0cells0except:

Beta0chain0Locus0and0Gamma0Chain0Locus0-0ans✔If0the0___________
of0a0TCR0is0successfully0rearranged,0then0the0_______
deleted0and0inactivated0due0to0its0location.

Double0positive0and0Mature0T-cell0in0a0lymph0node0-0ans✔During0T-
cell0maturation,0RAG-10and0RAG-20will0be0expressed0in0which0of0the0following

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Written in: 2025/2026
Type: Exam (elaborations)
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