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PCB 3233 Lab 9: Antiglobulin Test (Coombs Test) Questions and Answers with Complete Solutions | New Update 2026 | University of Central Florida

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PCB 3233 Lab 9: Antiglobulin Test (Coombs Test) Questions and Answers with Complete Solutions | New Update 2026 | University of Central Florida

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PCB 3233 Lab 9: Antiglobulin Test (Coombs Test)
Questions and Answers with Complete Solutions |
New Update 2026 | University of Central Florida

What is our antibody in this lab? - ANSWERS Anti-human globulin


What is affinity? - ANSWERS Strength of bond between a single antigen and
antibody


Is affinity IgG or IgM? - ANSWERS IgG


What is avidity? - ANSWERS Strength of the binding of several antigens and
antibodies


Is avidity IgG or IgM? - ANSWERS IgM


What are the variables in this lab? - ANSWERS - Immunoglobulin class


- Affinity


- Cell to cell interactions


Is agglutination visible with two IgG molecules? - ANSWERS No

, Is agglutination visible with IgM molecules? - ANSWERS Yes


How do we observe antigen-antibody reactions in transfusion testing? -
ANSWERS Observing by agglutination


When do IgM antibodies agglutinate? - ANSWERS Immediately


What kind of test do IgG antibodies require to be detected? - ANSWERS
Antiglobulin test (Coombs test)


What are the two types of antiglobulin tests? - ANSWERS Indirect and direct


What does indirect antiglobulin test do? - ANSWERS Detects IgG antibodies in
serum


What does direct antiglobulin test do? - ANSWERS Detects IgG antibodies on
red cells


In this lab, which test is indirect? - ANSWERS Testing mom's serum


In this lab, which test is direct? - ANSWERS Testing baby's red blood cells


What is the unknown in this lab? - ANSWERS IgG antibodies


AHG applications? - ANSWERS Indirect Coombs and direct Coombs

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