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PCB 3233 Exam 2 Questions and Correct Answers (verified answers) | Graded A+ | New Update 2025 | University of Central Florida

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PCB 3233 Exam 2 Questions and Correct Answers (verified answers) | Graded A+ | New Update 2025 | University of Central Florida

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PCB 3233 Exam 2 Questions and Correct
Answers (verified answers) | Graded A+ | New
Update 2025 | University of Central Florida

What are two cells that use receptors to distinguish between self and non-self
cells? - ANSWERS -Macrophages
-NK Cells


C3b is a ligand for - ANSWERS Macrophage CR1


CR3 & CR4 - ANSWERS Recognize iC3b & other ligands including LPS


Lectins - ANSWERS Carbohydrates-binding proteins
ex: Mannose & glucose receptors


Scavenger Receptors - ANSWERS Prefer molecules that are negatively charged
like nucleic acids, LPS.


Phagocytic Receptors - ANSWERS Bind directly to microbial surface
components


What do surface receptors promote? - ANSWERS Phagocytosis


PRR's bind to - ANSWERS PAMPs on pathogens

, Receptors that detect microbial products signal what? - ANSWERS -
Macrophage activation
-Cytokine Secretion


Toll-Like Receptors (TLR) - ANSWERS -10 receptors
-Has specificities for several microbial products


TLR-4 - ANSWERS -Senses LPS
-Found on macrophages


What can LPS cause? - ANSWERS Septic Shock


What is LPS known for being? - ANSWERS Endotoxin


What is local accumulation of fluid accompanied by? - ANSWERS Swelling,
redness, heat, & pain


What does increased dilation cause? - ANSWERS Reduced blood flow


Complement receptors 3&4 (Mac-1, CD11b, CD8) target what? - ANSWERS
Bacteria & Fungi


CD14 binds to what? - ANSWERS -LPS
-Peptidoglycan

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