HNG 540 EXAM 3 QUESTIONS AND ANSWERS
1. what is colchicine- Answers - type of anti inflammatory med
anti gout agents used in acute phase (gout attack) can also use low dose for prophylaxis
works by inhibiting microtubule formation in neutrophils which reduces inflammation (works by decreasing inflamma- tory
response)
may cause GI upset/ diarrhea and will need renal adjustment
2. Allopurinol- Answers - med class is called xanthine oxidase inhibitors
works by decreasing the production of uric acid in body by inhibiting xanthine oxidase
used for long term treatment of gout/ uric acid kidney stones and tumor lysis syndrome
started after a flare up resolves and may trigger gout flares when stating medication
3. probenecid- Answers - class of drugs called uricosurics
works by inhibiting tubular reabsorption of uric acid leading to an increase in uic acid excretion- lowering high levels of
uric acid in the body by helping the kidneys eliminate it
used for long term control
not ettective in renal impairment patients - any type of kidney failure disease pt will not take this med
encourage high fluid intake
4. 2 types of gout patients- Answers - 1) under excretors - kidneys dont get rid of enough uric acid most gout
cases
2)overr producers- body produces too much uric acid
5. how to find out if pt is an under excreto or over producer for uric acid- Answers - 24
hour urine uric acid test
1/
15
, if there is low uric acid in urine but high in blood then pt is under
excetor if there is high uric acid in both blood and urine then pt is
over producer
under excretor get prescribed probenecid which works by helping they kidney excrete uric acid
over producer are treated with allopurinol which reduces uric acid production
2/
15
1. what is colchicine- Answers - type of anti inflammatory med
anti gout agents used in acute phase (gout attack) can also use low dose for prophylaxis
works by inhibiting microtubule formation in neutrophils which reduces inflammation (works by decreasing inflamma- tory
response)
may cause GI upset/ diarrhea and will need renal adjustment
2. Allopurinol- Answers - med class is called xanthine oxidase inhibitors
works by decreasing the production of uric acid in body by inhibiting xanthine oxidase
used for long term treatment of gout/ uric acid kidney stones and tumor lysis syndrome
started after a flare up resolves and may trigger gout flares when stating medication
3. probenecid- Answers - class of drugs called uricosurics
works by inhibiting tubular reabsorption of uric acid leading to an increase in uic acid excretion- lowering high levels of
uric acid in the body by helping the kidneys eliminate it
used for long term control
not ettective in renal impairment patients - any type of kidney failure disease pt will not take this med
encourage high fluid intake
4. 2 types of gout patients- Answers - 1) under excretors - kidneys dont get rid of enough uric acid most gout
cases
2)overr producers- body produces too much uric acid
5. how to find out if pt is an under excreto or over producer for uric acid- Answers - 24
hour urine uric acid test
1/
15
, if there is low uric acid in urine but high in blood then pt is under
excetor if there is high uric acid in both blood and urine then pt is
over producer
under excretor get prescribed probenecid which works by helping they kidney excrete uric acid
over producer are treated with allopurinol which reduces uric acid production
2/
15
