Pagek1kofk822
TEST BANK k
Katzung's Basic and Clinical Pharm
k k k k
acology, 16th Edition
k k k
by Todd W. Vanderah, Chapters 1 - 66
k k k k k k k k
Katzung'skBasickandkClinicalkPharmacology
, Pagek2kofk822
Table kkkk
tx of tx Contents
kk kk kk kkkk kkkk kk
1. tx kkkk
Introduction: tx The tx Nature tx of tx Drugs tx & tx Drug tx Development tx & tx Regulation
kk kk kkkk
2. tx Drug tx Receptors tx & tx Pharmacodynamics
kk
3. kkkk
tx kk kk kkkk kk kk kkkk kk
Pharmacokinetics tx & tx Pharmacodynamics: tx Rational tx Dosing tx & tx the tx Time tx Course tx of tx Drug tx Action
kk kk
4. tx Drug tx Biotransformation
kk
5. tx Pharmacogenomics
kk
6. tx Introduction kkkk kk tx to tx Autonomic tx Pharmacology
kk
7. tx kkkk
Cholinoceptor-Activating tx & tx Cholinesterase-Inhibiting kk tx Drugs
kk
8. tx kk
Cholinoceptor-Blocking tx Drugs
kk
9. tx Adrenoceptor kk kkkk tx Agonists tx & tx Sympathomimetic kk tx Drugs
kk
10. tx Adrenoceptor kk kk tx Antagonist tx Drugs
11. kktx kk Antihypertensive tx Agents
12. kk kkkk kk kkkk kk
tx Vasodilators tx & tx the tx Treatment tx of tx Angina tx Pectoris
13. kk kk kkkk kk
tx Drugs tx Used tx in tx Heart tx Failure
14. kk kk kkkk kk
tx Agents tx Used tx in tx Cardiac tx Arrhythmias
15. kk kk
tx Diuretic tx Agents
16. kk kk kkkk kk kk
tx Histamine, tx Serotonin, tx & tx the tx Ergot tx Alkaloids
17. kk kk
tx Vasoactive tx Peptides
18. kk kk kk
tx Thekk kk tx Eicosanoids: tx Prostaglandins, tx Thromboxanes, tx Leukotrienes, kkkk kk
tx & tx Related tx Compounds
19. kk kk
tx Nitric tx Oxide
20. kk kk kkkk
tx Drugs tx Used tx in tx Asthma
21. kktx kkkk kk
Introduction kkkk kk tx to tx the tx Pharmacology tx of tx CNS tx Drugs
22. kktx kk
Sedative-Hypnotic tx Drugs
23. kktx The kk tx Alcohols
24. kktx kk
Antiseizure tx Drugs
25. kktx Generalkk tx Anesthetics
26. kktx Local kk tx Anesthetics
27. kktx kk kk
Skeletal tx Muscle tx Relaxants
28. kktx kk kkkk
Pharmacologic kkkk kk tx Management tx of tx Parkinsonism tx & tx Other tx Movement kk tx Disorders
29. kktx kk kkkk
Antipsychotic tx Agents tx & tx Lithium
30. kktx kk
Antidepressant tx Agents
31. kktx Opioidkk kkkk tx Agonists tx & tx Antagonists
32. kktx Drugs kkkk tx of tx Abuse
33. kktx Agents kk kkkk kktx kk kk Used tx in tx Cytopenias; tx Hematopoietic tx Growth tx Factors
34. kktx Drugs kk kkkk kkkk
tx Used tx in tx Disorders tx of tx Coagulation
35. kktx Agents kk kkkk tx Used tx in tx Dyslipidemia
36. kktx kk
Nonsteroidal kk kk kk kk kktx Anti-Inflammatory tx Drugs, tx Disease-Modifying tx Antirheumatic tx Drugs, tx Nonopioid kk tx kkkk kk kkkk
Analgesics, tx & tx Drugs tx Used tx in tx Gout
37. kktx kkkk kk
Hypothalamic tx & tx Pituitary tx Hormones
38. kktx Thyroidkkkk kk tx & tx Antithyroid tx Drugs
39. kktx kkkk kk
Adrenocorticosteroids tx & tx Adrenocortical tx Antagonists
40. kktx The kk kk kkkk
tx Gonadal tx Hormones tx & tx Inhibitors
41. kktx kk kkkk kk
Pancreatic tx Hormones tx & tx Antidiabetic tx Drugs
42. kktx Agents kk kk kk kk kk
tx That tx Affect tx Bone tx Mineral tx Homeostasis
43. kk kkkk kk kk kkkk
tx Beta-Lactam kk tx & tx Other tx Cell tx Wall- tx & tx Membrane-Active tx Antibiotics
44. kktxkk kk kk kk
Tetracyclines,kkkk tx Macrolides, tx Clindamycin, tx Chloramphenicol, tx Streptogramins, tx & tx Oxazolidinones
45. kktx kkkk
Aminoglycosides tx & tx Spectinomycin
46. kktxkk kkkk
Sulfonamides, tx Trimethoprim, tx & tx Quinolones
47. kktx kkAntimycobacterial tx Drugs
48. kk kk
tx Antifungal tx Agents
49. kk kk
tx Antiviral tx Agents
50. kktxkk kk kk kk kkkk
Miscellaneous tx Antimicrobial tx Agents; tx Disinfectants, tx Antiseptics, tx & tx Sterilants
51. kk kk kkkk
tx kk
Clinical tx Use tx of tx Antimicrobial tx Agents
52. kktxkk Antiprotozoal tx Drugs
53. kk kk
tx kkkk kk
Clinical kk tx Pharmacology tx of tx the tx Antihelminthic tx Drugs
54. kk kk
tx Cancer tx Chemotherapy
55. kktx Immunopharmacology
56. kk kkkk kk
tx kkkk
Introduction tx to tx Toxicology: tx Occupational tx & tx Environmental
57. kk kk kk kkkk
tx Heavy tx Metal tx Intoxication tx & tx Chelators
58. kk kkkk kk kk
tx Management tx of tx the tx Poisoned tx Patient
59. kktx Special kk kkkk kkkk kk
tx Aspects tx of tx Perinatal tx & tx Pediatric tx Pharmacology
60. kktx Special kk kkkk kk
tx Aspects tx of tx Geriatric tx Pharmacology
61. kktx kk
Dermatologic tx Pharmacology
62. kktx Drugs kk kkkk kk kkkk
tx kk Used tx in tx the tx Treatment tx of tx Gastrointestinal tx Diseases
63. kktx kkkk kk kkkk
Therapeutic kk tx & tx Toxic tx Potential tx of tx Over-the-Counter tx Agents
64. kktx Dietary kk kkkk kk
tx Supplements tx & tx Herbal tx Medications
65. kktx Rational kk kkkk kk tx Prescribing tx & tx Prescription tx Writing
Katzung'skBasickandkClinicalkPharmacology
, Pagek3kofk822
kk
66. tx Important kk kk
tx Drug tx Interactions kkkk kk
tx & tx Their tx Mechanisms kktx
Chapter kkkk
tx 1. tx Introduction: kk kk kkkk kkkk kk
tx The tx Nature tx of tx Drugs tx & tx Drug tx Development kkkk
tx & tx Regulation
1.
Aknursekworkingkinkradiologykadministerskiodinektokakpatientkwhokiskhavi
ngkakcomputedktomographyk(CT)kscan.kTheknursekworkingkonkthekoncologyk
unitkadministerskchemotherapyktokpatientskwhokhavekcancer.kAtkthekPublickH
ealthkDepartment,kaknursekadministerskakmeasles-mumps-
rubellak(MMR)kvaccinektokak14-month-
oldkchildkaskakroutinekimmunization.kWhichkbranchkofkpharmacologykbestkde
scribeskthekactionskofkallkthreek nurses?
A) Pharmacoeconomics
B) Pharmacotherapeutics
C) Pharmacodynamics
D) Pharmacokinetics
ANSWER: B
Feedback:
Pharmacologykiskthekstudykofkthekbiologickeffectskofkchemicals.kNurseskareki
nvolvedkwithkclinicalkpharmacologykorkpharmacotherapeutics,kwhichkiskakbr
anchkofkpharmacologykthatkdealskwithkthekuseskofkdrugsktoktreat,kprevent,kan
dkdiagnosekdisease.kThekradiologyknursekiskadministeringkakdrugktokhelpkdiag
nosekakdisease.kThekoncologyknursekiskadministeringkakdrugktokhelpktreatkakdi
sease.kPharmacoeconomicskincludeskanykcostskinvolvedkinkdrugk therapy.
Pharmacodynamicskinvolveskhowkakdrugkaffectskthekbodykan
dkpharmacokineticskiskhowkthekbodykactskonkthekbody.
2.
Akphysiciankhaskorderedkintramusculark(IM)kinjectionskofkmorphine,kaknar
cotic,keveryk4khourskaskneededkforkpainkinkakmotorkvehiclekaccidentkvictim.k
Theknursekiskawarekthiskdrugkhaskakhighkabusekpotential.kUnderkwhatkcatego
rykwouldkmorphinekbekclassified?
A) SchedulekI
B) SchedulekII
Katzung'skBasickandkClinicalkPharmacology
, Pagek4kofk822
C) SchedulekIII
D) SchedulekIV
ANSWER: B
Feedback:
NarcoticskwithkakhighkabusekpotentialkarekclassifiedkaskSchedulekIIkdrugskbe
causekofkseverekdependencekliability.kSchedulekIkdrugskhavekhighkabusekpot
entialkandknokacceptedkmedicalkuse.kSchedulekIIIkdrugskhavekaklesserkabusek
potentialkthankIIkandkankacceptedkmedicalkuse.kSchedulekIVkdrugskhaveklowk
abusekpotentialkandklimitedkdependencek liability.
3.
WhenkinvolvedkinkphasekIIIkdrugkevaluationkstudies,kwhatkresponsibili
tieskwouldktheknursekhave?
A) Workingkwithkanimalskwhokarekgivenkexperimentalk drugs
B) Choosingkappropriatekpatientsktokbekinvolvedkinkthekdrugk study
C) Monitoringkandkobservingkpatientskcloselykforkadversek effects
D) Conductingkresearchktokdeterminekeffectivenesskofkthek drug
ANSWER: C
Feedback:
PhasekIIIkstudieskinvolvekusekofkakdrugkinkakvastkclinicalkpopulationkinkwhi
chkpatientskarekaskedktokrecordkanyksymptomsktheykexperiencekwhilektaking
kthekdrugs.kNurseskmaykbekresponsiblekforkhelpingkcollectkandkanalyzektheki
nformationktokbeksharedkwithkthekFoodkandkDrugkAdministrationk(FDA)kbu
tkwouldknotkconductkresearchkindependentlykbecauseknurseskdoknotkprescrib
ekmedications.kUsekofkanimalskinkdrugktestingkiskdonekinkthekpreclinicalktri
als.kSelectkpatientskwhokarekinvolvedkinkphasekIIkstudiesktokparticipatekinkst
udieskwherekthekparticipantskhavekthekdiseasekthekdrugkiskintendedktoktreat.k
Thesekpatientskarekmonitoredkcloselykforkdrugkactionkandkadversekeffects.k
PhasekIkstudieskinvolvekhealthykhumankvolunteerskwhokarekusuallykpaidkfor
ktheirkparticipation.kNurseskmaykobservekforkadversekeffectskandktoxicity.
4.
Whatkconceptkiskconsideredkwhenkgenerickdrugskareksubstitutedkforkbr
andknamekdrugs?
Katzung'skBasickandkClinicalkPharmacology
TEST BANK k
Katzung's Basic and Clinical Pharm
k k k k
acology, 16th Edition
k k k
by Todd W. Vanderah, Chapters 1 - 66
k k k k k k k k
Katzung'skBasickandkClinicalkPharmacology
, Pagek2kofk822
Table kkkk
tx of tx Contents
kk kk kk kkkk kkkk kk
1. tx kkkk
Introduction: tx The tx Nature tx of tx Drugs tx & tx Drug tx Development tx & tx Regulation
kk kk kkkk
2. tx Drug tx Receptors tx & tx Pharmacodynamics
kk
3. kkkk
tx kk kk kkkk kk kk kkkk kk
Pharmacokinetics tx & tx Pharmacodynamics: tx Rational tx Dosing tx & tx the tx Time tx Course tx of tx Drug tx Action
kk kk
4. tx Drug tx Biotransformation
kk
5. tx Pharmacogenomics
kk
6. tx Introduction kkkk kk tx to tx Autonomic tx Pharmacology
kk
7. tx kkkk
Cholinoceptor-Activating tx & tx Cholinesterase-Inhibiting kk tx Drugs
kk
8. tx kk
Cholinoceptor-Blocking tx Drugs
kk
9. tx Adrenoceptor kk kkkk tx Agonists tx & tx Sympathomimetic kk tx Drugs
kk
10. tx Adrenoceptor kk kk tx Antagonist tx Drugs
11. kktx kk Antihypertensive tx Agents
12. kk kkkk kk kkkk kk
tx Vasodilators tx & tx the tx Treatment tx of tx Angina tx Pectoris
13. kk kk kkkk kk
tx Drugs tx Used tx in tx Heart tx Failure
14. kk kk kkkk kk
tx Agents tx Used tx in tx Cardiac tx Arrhythmias
15. kk kk
tx Diuretic tx Agents
16. kk kk kkkk kk kk
tx Histamine, tx Serotonin, tx & tx the tx Ergot tx Alkaloids
17. kk kk
tx Vasoactive tx Peptides
18. kk kk kk
tx Thekk kk tx Eicosanoids: tx Prostaglandins, tx Thromboxanes, tx Leukotrienes, kkkk kk
tx & tx Related tx Compounds
19. kk kk
tx Nitric tx Oxide
20. kk kk kkkk
tx Drugs tx Used tx in tx Asthma
21. kktx kkkk kk
Introduction kkkk kk tx to tx the tx Pharmacology tx of tx CNS tx Drugs
22. kktx kk
Sedative-Hypnotic tx Drugs
23. kktx The kk tx Alcohols
24. kktx kk
Antiseizure tx Drugs
25. kktx Generalkk tx Anesthetics
26. kktx Local kk tx Anesthetics
27. kktx kk kk
Skeletal tx Muscle tx Relaxants
28. kktx kk kkkk
Pharmacologic kkkk kk tx Management tx of tx Parkinsonism tx & tx Other tx Movement kk tx Disorders
29. kktx kk kkkk
Antipsychotic tx Agents tx & tx Lithium
30. kktx kk
Antidepressant tx Agents
31. kktx Opioidkk kkkk tx Agonists tx & tx Antagonists
32. kktx Drugs kkkk tx of tx Abuse
33. kktx Agents kk kkkk kktx kk kk Used tx in tx Cytopenias; tx Hematopoietic tx Growth tx Factors
34. kktx Drugs kk kkkk kkkk
tx Used tx in tx Disorders tx of tx Coagulation
35. kktx Agents kk kkkk tx Used tx in tx Dyslipidemia
36. kktx kk
Nonsteroidal kk kk kk kk kktx Anti-Inflammatory tx Drugs, tx Disease-Modifying tx Antirheumatic tx Drugs, tx Nonopioid kk tx kkkk kk kkkk
Analgesics, tx & tx Drugs tx Used tx in tx Gout
37. kktx kkkk kk
Hypothalamic tx & tx Pituitary tx Hormones
38. kktx Thyroidkkkk kk tx & tx Antithyroid tx Drugs
39. kktx kkkk kk
Adrenocorticosteroids tx & tx Adrenocortical tx Antagonists
40. kktx The kk kk kkkk
tx Gonadal tx Hormones tx & tx Inhibitors
41. kktx kk kkkk kk
Pancreatic tx Hormones tx & tx Antidiabetic tx Drugs
42. kktx Agents kk kk kk kk kk
tx That tx Affect tx Bone tx Mineral tx Homeostasis
43. kk kkkk kk kk kkkk
tx Beta-Lactam kk tx & tx Other tx Cell tx Wall- tx & tx Membrane-Active tx Antibiotics
44. kktxkk kk kk kk
Tetracyclines,kkkk tx Macrolides, tx Clindamycin, tx Chloramphenicol, tx Streptogramins, tx & tx Oxazolidinones
45. kktx kkkk
Aminoglycosides tx & tx Spectinomycin
46. kktxkk kkkk
Sulfonamides, tx Trimethoprim, tx & tx Quinolones
47. kktx kkAntimycobacterial tx Drugs
48. kk kk
tx Antifungal tx Agents
49. kk kk
tx Antiviral tx Agents
50. kktxkk kk kk kk kkkk
Miscellaneous tx Antimicrobial tx Agents; tx Disinfectants, tx Antiseptics, tx & tx Sterilants
51. kk kk kkkk
tx kk
Clinical tx Use tx of tx Antimicrobial tx Agents
52. kktxkk Antiprotozoal tx Drugs
53. kk kk
tx kkkk kk
Clinical kk tx Pharmacology tx of tx the tx Antihelminthic tx Drugs
54. kk kk
tx Cancer tx Chemotherapy
55. kktx Immunopharmacology
56. kk kkkk kk
tx kkkk
Introduction tx to tx Toxicology: tx Occupational tx & tx Environmental
57. kk kk kk kkkk
tx Heavy tx Metal tx Intoxication tx & tx Chelators
58. kk kkkk kk kk
tx Management tx of tx the tx Poisoned tx Patient
59. kktx Special kk kkkk kkkk kk
tx Aspects tx of tx Perinatal tx & tx Pediatric tx Pharmacology
60. kktx Special kk kkkk kk
tx Aspects tx of tx Geriatric tx Pharmacology
61. kktx kk
Dermatologic tx Pharmacology
62. kktx Drugs kk kkkk kk kkkk
tx kk Used tx in tx the tx Treatment tx of tx Gastrointestinal tx Diseases
63. kktx kkkk kk kkkk
Therapeutic kk tx & tx Toxic tx Potential tx of tx Over-the-Counter tx Agents
64. kktx Dietary kk kkkk kk
tx Supplements tx & tx Herbal tx Medications
65. kktx Rational kk kkkk kk tx Prescribing tx & tx Prescription tx Writing
Katzung'skBasickandkClinicalkPharmacology
, Pagek3kofk822
kk
66. tx Important kk kk
tx Drug tx Interactions kkkk kk
tx & tx Their tx Mechanisms kktx
Chapter kkkk
tx 1. tx Introduction: kk kk kkkk kkkk kk
tx The tx Nature tx of tx Drugs tx & tx Drug tx Development kkkk
tx & tx Regulation
1.
Aknursekworkingkinkradiologykadministerskiodinektokakpatientkwhokiskhavi
ngkakcomputedktomographyk(CT)kscan.kTheknursekworkingkonkthekoncologyk
unitkadministerskchemotherapyktokpatientskwhokhavekcancer.kAtkthekPublickH
ealthkDepartment,kaknursekadministerskakmeasles-mumps-
rubellak(MMR)kvaccinektokak14-month-
oldkchildkaskakroutinekimmunization.kWhichkbranchkofkpharmacologykbestkde
scribeskthekactionskofkallkthreek nurses?
A) Pharmacoeconomics
B) Pharmacotherapeutics
C) Pharmacodynamics
D) Pharmacokinetics
ANSWER: B
Feedback:
Pharmacologykiskthekstudykofkthekbiologickeffectskofkchemicals.kNurseskareki
nvolvedkwithkclinicalkpharmacologykorkpharmacotherapeutics,kwhichkiskakbr
anchkofkpharmacologykthatkdealskwithkthekuseskofkdrugsktoktreat,kprevent,kan
dkdiagnosekdisease.kThekradiologyknursekiskadministeringkakdrugktokhelpkdiag
nosekakdisease.kThekoncologyknursekiskadministeringkakdrugktokhelpktreatkakdi
sease.kPharmacoeconomicskincludeskanykcostskinvolvedkinkdrugk therapy.
Pharmacodynamicskinvolveskhowkakdrugkaffectskthekbodykan
dkpharmacokineticskiskhowkthekbodykactskonkthekbody.
2.
Akphysiciankhaskorderedkintramusculark(IM)kinjectionskofkmorphine,kaknar
cotic,keveryk4khourskaskneededkforkpainkinkakmotorkvehiclekaccidentkvictim.k
Theknursekiskawarekthiskdrugkhaskakhighkabusekpotential.kUnderkwhatkcatego
rykwouldkmorphinekbekclassified?
A) SchedulekI
B) SchedulekII
Katzung'skBasickandkClinicalkPharmacology
, Pagek4kofk822
C) SchedulekIII
D) SchedulekIV
ANSWER: B
Feedback:
NarcoticskwithkakhighkabusekpotentialkarekclassifiedkaskSchedulekIIkdrugskbe
causekofkseverekdependencekliability.kSchedulekIkdrugskhavekhighkabusekpot
entialkandknokacceptedkmedicalkuse.kSchedulekIIIkdrugskhavekaklesserkabusek
potentialkthankIIkandkankacceptedkmedicalkuse.kSchedulekIVkdrugskhaveklowk
abusekpotentialkandklimitedkdependencek liability.
3.
WhenkinvolvedkinkphasekIIIkdrugkevaluationkstudies,kwhatkresponsibili
tieskwouldktheknursekhave?
A) Workingkwithkanimalskwhokarekgivenkexperimentalk drugs
B) Choosingkappropriatekpatientsktokbekinvolvedkinkthekdrugk study
C) Monitoringkandkobservingkpatientskcloselykforkadversek effects
D) Conductingkresearchktokdeterminekeffectivenesskofkthek drug
ANSWER: C
Feedback:
PhasekIIIkstudieskinvolvekusekofkakdrugkinkakvastkclinicalkpopulationkinkwhi
chkpatientskarekaskedktokrecordkanyksymptomsktheykexperiencekwhilektaking
kthekdrugs.kNurseskmaykbekresponsiblekforkhelpingkcollectkandkanalyzektheki
nformationktokbeksharedkwithkthekFoodkandkDrugkAdministrationk(FDA)kbu
tkwouldknotkconductkresearchkindependentlykbecauseknurseskdoknotkprescrib
ekmedications.kUsekofkanimalskinkdrugktestingkiskdonekinkthekpreclinicalktri
als.kSelectkpatientskwhokarekinvolvedkinkphasekIIkstudiesktokparticipatekinkst
udieskwherekthekparticipantskhavekthekdiseasekthekdrugkiskintendedktoktreat.k
Thesekpatientskarekmonitoredkcloselykforkdrugkactionkandkadversekeffects.k
PhasekIkstudieskinvolvekhealthykhumankvolunteerskwhokarekusuallykpaidkfor
ktheirkparticipation.kNurseskmaykobservekforkadversekeffectskandktoxicity.
4.
Whatkconceptkiskconsideredkwhenkgenerickdrugskareksubstitutedkforkbr
andknamekdrugs?
Katzung'skBasickandkClinicalkPharmacology
