NURS 5315 ADVANCED PATHOPHYSIOLOGY
2025/2026 EXAM 1 QUESTIONS WITH CORRECT
ANSWERS ACTUAL EXAM UTA
Alpha Fetoprotein Origin
Liver and germ cell tumors
Carcinoembryonic Antigen
GI, pancreas, lung, breast tumors
Beta Human Chorionic gonadotropin origin
germ cell tumors
Prostate Specific Antigen
prostate tumors
Carcino-
from epithelial tissue- renal cell carcinoma
Sarco-
from connective tissue- chondrosarcoma
-oma
benign tumor- lipoma
Carcinoma in situ
preinvasive epithelial malignant tumors of glandular or squamous cells- cervix
-blastoma
from blasts or immature cells- neuroblastoma
, Lung ca metastasis
Multiple organs including brain
Colorectal ca metastasis
Liver, lungs
Testicular ca metastasis
Liver, lungs, brain
Prostate ca metastasis
Bones (especially lumbar spine), liver
Breast ca metastasis
Liver, lungs, brain, bones
Free radical and ROS
E. normal byproduct of ATP production, will overwhelm the mitochondria- exhaust intracellular
antioxidants
P. lipid peroxidation, damage proteins, fragment DNA
C.M. development in Alzheimer's, heart disease, Parkinson's disease, Amyotrophic Lateral
Sclerosis
Ethanol
E. mood altering drug, long term effects on liver and nutritional status
P. metabolized by liver, generates free radicals
C.M. CNS depression, nutrient deficiencies-Mag, Vit B6, thiamine, PO4, inflammation and fatty
infiltration of liver, hepatomegaly, leads to liver failure irreversible
Oncosis
Na and H2O enter cell and cause swelling. Organ increases in weight, becomes distended and
pale. Associated with high fever, hypocalcemia, certain infections
Fatty Infiltration
2025/2026 EXAM 1 QUESTIONS WITH CORRECT
ANSWERS ACTUAL EXAM UTA
Alpha Fetoprotein Origin
Liver and germ cell tumors
Carcinoembryonic Antigen
GI, pancreas, lung, breast tumors
Beta Human Chorionic gonadotropin origin
germ cell tumors
Prostate Specific Antigen
prostate tumors
Carcino-
from epithelial tissue- renal cell carcinoma
Sarco-
from connective tissue- chondrosarcoma
-oma
benign tumor- lipoma
Carcinoma in situ
preinvasive epithelial malignant tumors of glandular or squamous cells- cervix
-blastoma
from blasts or immature cells- neuroblastoma
, Lung ca metastasis
Multiple organs including brain
Colorectal ca metastasis
Liver, lungs
Testicular ca metastasis
Liver, lungs, brain
Prostate ca metastasis
Bones (especially lumbar spine), liver
Breast ca metastasis
Liver, lungs, brain, bones
Free radical and ROS
E. normal byproduct of ATP production, will overwhelm the mitochondria- exhaust intracellular
antioxidants
P. lipid peroxidation, damage proteins, fragment DNA
C.M. development in Alzheimer's, heart disease, Parkinson's disease, Amyotrophic Lateral
Sclerosis
Ethanol
E. mood altering drug, long term effects on liver and nutritional status
P. metabolized by liver, generates free radicals
C.M. CNS depression, nutrient deficiencies-Mag, Vit B6, thiamine, PO4, inflammation and fatty
infiltration of liver, hepatomegaly, leads to liver failure irreversible
Oncosis
Na and H2O enter cell and cause swelling. Organ increases in weight, becomes distended and
pale. Associated with high fever, hypocalcemia, certain infections
Fatty Infiltration
