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Chapterl01:lDruglRegulation,lActions,landlResponses
Workmanl&lLaCharity:lUnderstandinglPharmacology:lEssentialslforlMedicationlSafety,l3rd Editlio ai
n
MULTIPLElCHOICElBlASI
ClCONCEPTS
1. Whichlhealthlcarelprofessionallhaslthelmajorlresponsibilitylforldispensinglprescribed l d ai
rugslunderltheldirectionloflalpharmacist?
a. Physician
b Nurselpractitioner
.
c. Licensedlnurse
d Pharmacy technician ai
.
ANS:l l D
Thelphysicianlandlnurselpractitionerlhavelthelmajorlresponsibilitylforlprescribingldrugs,lnotldisplen
singlthem.lThellicensedlnurselhaslthelprimarylresponsibilitylforladministeringldrugs,lalthough l und a
erlsomelcircumstanceslallicensedlnurselmayldispenselprescribedldrugslbutlthislis notlhislorlhelrlmajor
ai
lresponsibilitylinldrugltherapy.lThelpharmacyltechnicianlhaslthelmajorlresponsibilitylofldlispensing ai
prescribedldrugslunderltheldirectionloflallicensedlpharmacist.
DIF:l l CognitivelLevel:lRememberingl l l l REF:l l p.l3
2. Whichltermldescribesltheleffectloflaldruglthatlimproveslbodylfunction?
a. Sideleffect
b Intended action
ai
.
c. Adverselreaction
d Idiosyncraticlresponse
.
ANS:l l B
Thelpurposelofldrugltherapylisltoltakelaldrugltolprevent,lreduce,lorlcorrectlalhealthlproblem.lThis
lresponselislanyldrug’slintendedlactionlalsolknownlaslaltherapeuticlresponse.
DIF: CognitivelLevel:lRemembering REF: p.l3
3. Whichltypelofldruglnamelisl―owned‖lbylthelcompanylthatlmanufactureslit?
a. Genericlname
b Chemicallname
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.
c. Categorylname
d Trade name ai
.
ANS: D
Thelchemicallnamelislaldrug’slexactlchemicallcomposition.lThelgenericlnamelislthelnamelassiglnedlt
oltheldruglbylthelU.S.lAdoptedlNameslCouncillandlislnotlownedlbylanyone.lThelcategorylnlamelrefersl
toltheltypelofldrugl(whatlitldoeslorlwhatlitlislusedlfor)landlislnotlanlactual druglname.lTheltradelnamel(b
ai
randlname)lislthelnamelprovided andlowned bylalspecificldrug’slmanufacturer
ai ai
.
DIF: CognitivelLevel:lRemembering REF: p.l4
4. Which drug or drug class is a ―high alert‖ drug?
ai ai ai ai ai ai ai ai ai
a. Penicillin
b Insulin
.
c. NSAIDs
d Calcium
.
ANS: B
Alhighlalertldruglislonelinlwhichlharmlisllikelyltolresultliflgivenlatlthelwrong dose,ltolthelwrong platientai ai
,lorlnotlgivenltolthelcorrectlpatient.lDrugslclassifiedlaslhighlalertldrugslincludelpotassium, nlarcoticsl( ai
opioids),linsulin,lcancerlchemotherapyldrugs,landlheparinl(orlanyldruglthatlstronglylafflectslbloodlclo
tting).lPenicillin,lNSAIDs,landlcalciumlarelnotlconsideredlhighlalertldrugs.
DIF: CognitivelLevel:lRemembering REF: p.l4
5. Whatlisltheltermlforlaldruglthatlhaslthelsamelactionlaslalnaturallyloccurringlbodylhor
monelorlenzyme?
a. Agonist
b Blockinglagent
.
c. Chemical
d Duplicator
.
ANS: A
Aldruglagonistlislanlextrinsicldruglthatlactivateslthelreceptorlsitesloflalcelllandlmimicslthe l action ai
sloflnaturallyloccurringlbodylsubstancesl(intrinsicldrugs).lAblockinglagentlislaldrug
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antagonist.lAchemicallwouldlnotlnecessarilylbelaldruglatlall.lAduplicatorlislnot alpharmacologic tler ai ai
m.
DIF:l l CognitivelLevel:lRememberingl l l l REF:l l pp.l6-7
6. Whichltermldescribeslhowlthelbodylaffectsldrug activity? ai
a. Druglpotency
b Pharmacodynamics
.
c. Therapeuticl effect
d Pharmacokinetics
.
ANS:l l D
Theltermlpharmacokineticslrefersltoldruglmetabolismlandlhowlthelbodylchangeslaldrug.lPharmaclod
ynamicslrefersltolhowlaldruglworksltolchangelbodylfunction.lDruglpotencylreferslto howlstrongllylorlt ai
olwhatldegreelaldruglexertslitsleffects.lTheltherapeuticleffectlislcloserltolpharmacodynamics,lmeanin
glhowlaldruglworksltolchangelbodylfunction.
DIF:l l CognitivelLevel:lRememberingl l l l REF:l l p.l10
7. InlthelUnitedlStates,lwhichlgrouplislresponsiblelforlenforcing establishedlstandardslforldr ai
uglmanufacturing?
a. U.S.lPharmacopeia
b NationallInstitutesloflHealth
.
c. Food and Drug Administration
ai ai ai
d AssociationloflPharmaceuticallManufacturers
.
ANS:l l C
ThelstandardslforldruglmanufacturelarelestablishedlbylthelU.S.lPharmacopeia.lTheselstandardslalrel
enforcedlbylthelFoodlandlDruglAdministration.lNeitherlthelNationallInstitutesloflHealthlnorthlelAss
ociationloflPharmaceuticallManufacturerslhaslanylauthorityltolenforceldruglstandards.
DIF:l l CognitivelLevel:lRememberingl l l l REF:l l p.l5
8. Which factor is a major disadvantage of the transdermal drug delivery route?
ai ai ai ai ai ai ai ai ai ai ai
a. Onlylalprescriberlcanladministerldrugslbyltheltransdermallroute.
b Transdermalldrugslmustlbelsterilelratherlthanlclean.
.
c. Firstlpassldrugllosslbylthislroutelislthelmostlextensive.
d Drug absorption is dependent on adequate circulation.
ai ai ai ai ai ai