https://www.stuvia.com/
TEST BANK FOR MODERN BLOOD BANKING &
l l l l l l l
TRANSFUSION PRACTICES 7TH EDITION BY DE
l l l l l
NISE M HARMENING
l l
9780803668881 CHAPTER 1-
l l
29 COMPLETE GUIDE
l l
,https://www.stuvia.com/
Chapterl1lRBCslandlPlateletlPreservation:lHistoricallPerspectiveslandlCurrentlTrends
MultiplelChoice
Identifylthelchoicelthatlbestlcompleteslthelstatementlorlanswerslthelquestion.
1. Whichlmetaboliclpathwaylislresponsiblelforlgeneratingl90%loflthelATPlforlthelRBC?
a. Pentoselphosphatelshunt c. Glycolysis
b. Luebering-Rapoportlshunt d.l Methemoglobinlreductase
2. Alunitloflbloodlwaslreturnedltolthelbloodlbanklbeforelitlwaslspiked.lApparentlylthelpatient’slIVlfailed.lTheluni
tloflbloodlwasloutsidelthelbloodlbanklforl35lminutes.lWhichloflthelstatementslbelowlislmostlaccurate?
a. Thelunitloflbloodlshouldlbeldiscardedlimmediately.
b. Thelunitloflbloodlcanlbelreturnedltolinventory.
c. Thelunitloflbloodlmustlbeltransfusedlwithinl4lhourslorlbeldiscardedlatlthelendloflthatltime.
d. Thelunitloflbloodlmustlbeltransfusedlwithl24lhours.
3. Whatlislthelaverageldiameterloflalplatelet?
a. 5ltol10lµm c. 1ltol2lµm
b. 2ltol4lµm d.l l 4ltol6lµm
4. Inlthelnormallhemoglobin-
oxygenldissociationlcurve,lwhatlpercentagelofloxygenlislreleasedltoltheltissueslwhenlPO2l averagesl40lmml
Hg?
a. 75% c. 100%
b. 25% d.l 50%
5. Whatlfactorslarelknownltolinfluencelplateletlmetabolismlandlfunction?
a. Storageltemperature c. Plateletlcount
b. InitiallpH d.l Allloflthelabove
6. Whichloflthelfollowinglredlbloodlcelllmorphologieslmaylbelpresentlonlthelperipherallbloodlsmearlaslalresultlofll
ossloflRBClmembrane?
a. Spherocytes c. Burrlcells
b. Targetlcells d.l Schistocytes
7. Whatldoesltheltermlautologousltransfusionlreferlto?
a. Alparentldonatinglbloodlforlhislorlherlchild
b. Anlindividualldonatinglbloodlforlalfriend
c. Anlindividualldonatinglbloodlforlalrelative
d. Anlindividualldonatinglbloodlforlhislorlherlownltransfusion
8. Whatlislthelprimarylfunctionloflhemoglobin?
a. Ironlmetabolism c. Oxygenltransport
b. Porphyrinlsynthesis d.l Signalltransduction
9. Allloflthelfollowinglareasloflredlbloodlcelllbiologylarelcruciallforlnormallerythrocytelsurvivall except:
a. Cellularlmetabolism. c. SiteloflthelABOlantigenlattachment.
b. RBClmembrane. d.l Hemoglobinlstructure.
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l 10.l WhatlislthelcorrectlbiochemicallcompositionloflthelRBClmembrane?
a. 52%lprotein,l40%llipid,l8%lcarbohydrate
b. 40%lprotein,l8%llipid,l52%lcarbohydrate
c. 8%lprotein,l52%llipid,l40%lcarbohydrate
d. 8%llipid,l40%lcarbohydrate,l52%lprotein
l 11.l Allloflthelfollowinglbiochemicallchangeslarelassociatedlwithllossloflredlbloodlcelllviabilityluponlstorage
except:
a. DecreasedlpH. c. IncreasedlATPllevel.
b. Lossloflredlbloodlcelllfunction. d.l Decreasedlglucoselconsumption.
l 12.l Whichlredlbloodlcelllpreservativelhaslalstorageltimelofl35ldays?
a. ACD c. AS-1
b. CPDA-1 d.l l CPD
l 13.l ThelRBClmembranelislrelativelylpermeableltolallloflthelfollowinglexcept:
a. Chloride. c. Bicarbonate.
b. Sodium. d.l Water.
l 14.lWhatlpercentageloflplateletslislsequesteredlinlthelspleenlaslfunctionallreservelafterlbeinglreleasedlfromlthelbo
nelmarrow?
a. 30% c. 10%
b. 50% d.l l 25%
l 15.l Whatlislthelmajorlbiochemicallconsiderationlinlplateletlstorage?
a. Glucoselmetabolism c. Productionloflcarbonldioxide
b. Oxygenlsupply d.l RegulationloflpH
l 16.lWhatlwouldlthelhemoglobin-
oxygenldissociationlcurveldepictlinlalpatientlexhibitinglclinicallsignsloflalkalosis?
a. Normal c. Shiftltolthelright
b. Shiftltolthelleft d.l Noneloflthelabove
l 17.l Namelthelmainllipidlcomponentsloflalredlbloodlcelllmembrane.
a. Phospholipid c. Glycolipid
b. Sphingomyelin d.l GlycophorinlA
l 18.l ThelABOlbloodlgroupslwereldiscoveredlinl1901lbylwhom?
a. CharleslDrew c. LoutitlandlMollison
b. KarllLandsteiner d.l EdwardlLindeman
l 19.lAlstandinglorderloflplateletslwaslshippedltolyourlfacilitylbylyourlsupplier.lItlwaslinadvertentlylleftlinlthelcornerl
ofltheldepartmentluntilldiscoveredl36lhoursllater.lWhatlwouldlthelappropriatelactionlbelforlthelbloodlbanker?
a. Ifltheltemperaturelinlthelboxlwasl22l+/-
l2°ClandlthelplateletlswirllseemedlOK,litlwouldlbelOKltolacceptlthelunitlintolinventory.
b. Thelplateletslhavelfallenloutsidelthelsupplier’slqualitylassurance.lThelunitlshouldlbeldisca
rdedlbecauselthelpHlhaslprobablyldroppedltoollowlandlplateletlactivationlhaslbeenlcompro
mised.
c. Ifltheltemperaturelwasl1°Cltol6°ClandlthelplateletlswirllseemedlOK,litlwouldlbelOKlto
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acceptlthelunitlintolinventory.
d. IflthelplateletslappearedlOKlandlpassedlthelplateletlswirlltestlafterlbeinglplacedlonlthelag
itator,ltheylcouldlbelacceptedlintolthelinventory.
l 20.l Whichlmetaboliclpathwaylpermitslthelaccumulationlofl2,3ldiphosphoglyceratel(2,3-DPG)?
a. Glycolysis c. Pentoselphosphatelshunt
b. Luebering-Rapoportlshunt d.l Methemoglobinlreductase
l 21.l Allloflthelfollowinglarelconsistentlwithlal"shiftltolthelright"loflthelhemoglobin-oxygenldissociationlcurve
except:
a. Increasedl2,3-DPG.
b. 50%lO2l saturationltoltissues.
c. Decreasedl2,3-DPG.
d. DecreasedlhemoglobinlaffinitylforlO2.
l 22.l Whatlislthelnormallplateletlcountlrangelperlcubiclmillimeter?
a. 100ltol350 c. 50,000ltol200,000
b. 150,000ltol350,000 d.l 350,000ltol500,000
l 23.l Whatlcryoprotectivelagentlisladdedltolredlbloodlcellsluponlfreezing?
a. Dextrose c. Glycerol
b. Adsol d.l Allloflthelabove
l 24.l Iflplateletslareltolbelstoredlforl5ldayslonlalrotator,lwhatlisltheloptimallstorageltemperature?
a. 1°Cltol6°C c. 35°Cltol37°C
b. 20°Cltol24°C d.l 1°Cltol10°C
l 25.l Whatlroleldolplateletslplaylinlhemostasis?
a. Maintenanceloflvascularlintegrity
b. Initiallarrestloflbleedinglbylplateletlpluglformation
c. Stabilizationloflthelhemostaticlplug
d. Allloflthelabove
l 26.l Whichloflthelfollowinglbestldescribesl"integral"lmembranelproteins?
a. Residelatlthelcytoplasmiclsurfaceloflmembrane
b. Spanlthelentirelmembranelsurface
c. Formlthelredlbloodlcelllcytoskeleton
d. Noneloflthelabove
l 27.l Howlislstroma-freelhemoglobinlsolutionlprepared?
a. Outdatedlredlbloodlcellslarelconcentrated,landlstromalislremoved.
b. Outdatedlredlbloodlcellslareldilutedlwithlsaline,landlstromalislremoved.
c. Outdatedlredlbloodlcellslarellysed,landlstromalislremoved.
d. Noneloflthelabove
l 28.l WhatlislthelnormalllifelspanloflanlRBC?
a. 100ldays c. 120lhours
b. 120ldays d.l 2ldays
l 29.l RegardingllossloflRBClmembraneldeformability,lallloflthelfollowinglareltruelexcept:
a. IncreaselinlATPllevel.
b. DecreaselinlATPllevel.
Thislstudylsourcelwasldownloadedlbyl100000826342158lfromlCourseHero.comlonl09-15-2021l17:54:15lGMTl-05:00
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TEST BANK FOR MODERN BLOOD BANKING &
l l l l l l l
TRANSFUSION PRACTICES 7TH EDITION BY DE
l l l l l
NISE M HARMENING
l l
9780803668881 CHAPTER 1-
l l
29 COMPLETE GUIDE
l l
,https://www.stuvia.com/
Chapterl1lRBCslandlPlateletlPreservation:lHistoricallPerspectiveslandlCurrentlTrends
MultiplelChoice
Identifylthelchoicelthatlbestlcompleteslthelstatementlorlanswerslthelquestion.
1. Whichlmetaboliclpathwaylislresponsiblelforlgeneratingl90%loflthelATPlforlthelRBC?
a. Pentoselphosphatelshunt c. Glycolysis
b. Luebering-Rapoportlshunt d.l Methemoglobinlreductase
2. Alunitloflbloodlwaslreturnedltolthelbloodlbanklbeforelitlwaslspiked.lApparentlylthelpatient’slIVlfailed.lTheluni
tloflbloodlwasloutsidelthelbloodlbanklforl35lminutes.lWhichloflthelstatementslbelowlislmostlaccurate?
a. Thelunitloflbloodlshouldlbeldiscardedlimmediately.
b. Thelunitloflbloodlcanlbelreturnedltolinventory.
c. Thelunitloflbloodlmustlbeltransfusedlwithinl4lhourslorlbeldiscardedlatlthelendloflthatltime.
d. Thelunitloflbloodlmustlbeltransfusedlwithl24lhours.
3. Whatlislthelaverageldiameterloflalplatelet?
a. 5ltol10lµm c. 1ltol2lµm
b. 2ltol4lµm d.l l 4ltol6lµm
4. Inlthelnormallhemoglobin-
oxygenldissociationlcurve,lwhatlpercentagelofloxygenlislreleasedltoltheltissueslwhenlPO2l averagesl40lmml
Hg?
a. 75% c. 100%
b. 25% d.l 50%
5. Whatlfactorslarelknownltolinfluencelplateletlmetabolismlandlfunction?
a. Storageltemperature c. Plateletlcount
b. InitiallpH d.l Allloflthelabove
6. Whichloflthelfollowinglredlbloodlcelllmorphologieslmaylbelpresentlonlthelperipherallbloodlsmearlaslalresultlofll
ossloflRBClmembrane?
a. Spherocytes c. Burrlcells
b. Targetlcells d.l Schistocytes
7. Whatldoesltheltermlautologousltransfusionlreferlto?
a. Alparentldonatinglbloodlforlhislorlherlchild
b. Anlindividualldonatinglbloodlforlalfriend
c. Anlindividualldonatinglbloodlforlalrelative
d. Anlindividualldonatinglbloodlforlhislorlherlownltransfusion
8. Whatlislthelprimarylfunctionloflhemoglobin?
a. Ironlmetabolism c. Oxygenltransport
b. Porphyrinlsynthesis d.l Signalltransduction
9. Allloflthelfollowinglareasloflredlbloodlcelllbiologylarelcruciallforlnormallerythrocytelsurvivall except:
a. Cellularlmetabolism. c. SiteloflthelABOlantigenlattachment.
b. RBClmembrane. d.l Hemoglobinlstructure.
Thislstudylsourcelwasldownloadedlbyl100000826342158lfromlCourseHero.comlonl09-15-2021l17:54:15lGMTl-05:00
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l 10.l WhatlislthelcorrectlbiochemicallcompositionloflthelRBClmembrane?
a. 52%lprotein,l40%llipid,l8%lcarbohydrate
b. 40%lprotein,l8%llipid,l52%lcarbohydrate
c. 8%lprotein,l52%llipid,l40%lcarbohydrate
d. 8%llipid,l40%lcarbohydrate,l52%lprotein
l 11.l Allloflthelfollowinglbiochemicallchangeslarelassociatedlwithllossloflredlbloodlcelllviabilityluponlstorage
except:
a. DecreasedlpH. c. IncreasedlATPllevel.
b. Lossloflredlbloodlcelllfunction. d.l Decreasedlglucoselconsumption.
l 12.l Whichlredlbloodlcelllpreservativelhaslalstorageltimelofl35ldays?
a. ACD c. AS-1
b. CPDA-1 d.l l CPD
l 13.l ThelRBClmembranelislrelativelylpermeableltolallloflthelfollowinglexcept:
a. Chloride. c. Bicarbonate.
b. Sodium. d.l Water.
l 14.lWhatlpercentageloflplateletslislsequesteredlinlthelspleenlaslfunctionallreservelafterlbeinglreleasedlfromlthelbo
nelmarrow?
a. 30% c. 10%
b. 50% d.l l 25%
l 15.l Whatlislthelmajorlbiochemicallconsiderationlinlplateletlstorage?
a. Glucoselmetabolism c. Productionloflcarbonldioxide
b. Oxygenlsupply d.l RegulationloflpH
l 16.lWhatlwouldlthelhemoglobin-
oxygenldissociationlcurveldepictlinlalpatientlexhibitinglclinicallsignsloflalkalosis?
a. Normal c. Shiftltolthelright
b. Shiftltolthelleft d.l Noneloflthelabove
l 17.l Namelthelmainllipidlcomponentsloflalredlbloodlcelllmembrane.
a. Phospholipid c. Glycolipid
b. Sphingomyelin d.l GlycophorinlA
l 18.l ThelABOlbloodlgroupslwereldiscoveredlinl1901lbylwhom?
a. CharleslDrew c. LoutitlandlMollison
b. KarllLandsteiner d.l EdwardlLindeman
l 19.lAlstandinglorderloflplateletslwaslshippedltolyourlfacilitylbylyourlsupplier.lItlwaslinadvertentlylleftlinlthelcornerl
ofltheldepartmentluntilldiscoveredl36lhoursllater.lWhatlwouldlthelappropriatelactionlbelforlthelbloodlbanker?
a. Ifltheltemperaturelinlthelboxlwasl22l+/-
l2°ClandlthelplateletlswirllseemedlOK,litlwouldlbelOKltolacceptlthelunitlintolinventory.
b. Thelplateletslhavelfallenloutsidelthelsupplier’slqualitylassurance.lThelunitlshouldlbeldisca
rdedlbecauselthelpHlhaslprobablyldroppedltoollowlandlplateletlactivationlhaslbeenlcompro
mised.
c. Ifltheltemperaturelwasl1°Cltol6°ClandlthelplateletlswirllseemedlOK,litlwouldlbelOKlto
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acceptlthelunitlintolinventory.
d. IflthelplateletslappearedlOKlandlpassedlthelplateletlswirlltestlafterlbeinglplacedlonlthelag
itator,ltheylcouldlbelacceptedlintolthelinventory.
l 20.l Whichlmetaboliclpathwaylpermitslthelaccumulationlofl2,3ldiphosphoglyceratel(2,3-DPG)?
a. Glycolysis c. Pentoselphosphatelshunt
b. Luebering-Rapoportlshunt d.l Methemoglobinlreductase
l 21.l Allloflthelfollowinglarelconsistentlwithlal"shiftltolthelright"loflthelhemoglobin-oxygenldissociationlcurve
except:
a. Increasedl2,3-DPG.
b. 50%lO2l saturationltoltissues.
c. Decreasedl2,3-DPG.
d. DecreasedlhemoglobinlaffinitylforlO2.
l 22.l Whatlislthelnormallplateletlcountlrangelperlcubiclmillimeter?
a. 100ltol350 c. 50,000ltol200,000
b. 150,000ltol350,000 d.l 350,000ltol500,000
l 23.l Whatlcryoprotectivelagentlisladdedltolredlbloodlcellsluponlfreezing?
a. Dextrose c. Glycerol
b. Adsol d.l Allloflthelabove
l 24.l Iflplateletslareltolbelstoredlforl5ldayslonlalrotator,lwhatlisltheloptimallstorageltemperature?
a. 1°Cltol6°C c. 35°Cltol37°C
b. 20°Cltol24°C d.l 1°Cltol10°C
l 25.l Whatlroleldolplateletslplaylinlhemostasis?
a. Maintenanceloflvascularlintegrity
b. Initiallarrestloflbleedinglbylplateletlpluglformation
c. Stabilizationloflthelhemostaticlplug
d. Allloflthelabove
l 26.l Whichloflthelfollowinglbestldescribesl"integral"lmembranelproteins?
a. Residelatlthelcytoplasmiclsurfaceloflmembrane
b. Spanlthelentirelmembranelsurface
c. Formlthelredlbloodlcelllcytoskeleton
d. Noneloflthelabove
l 27.l Howlislstroma-freelhemoglobinlsolutionlprepared?
a. Outdatedlredlbloodlcellslarelconcentrated,landlstromalislremoved.
b. Outdatedlredlbloodlcellslareldilutedlwithlsaline,landlstromalislremoved.
c. Outdatedlredlbloodlcellslarellysed,landlstromalislremoved.
d. Noneloflthelabove
l 28.l WhatlislthelnormalllifelspanloflanlRBC?
a. 100ldays c. 120lhours
b. 120ldays d.l 2ldays
l 29.l RegardingllossloflRBClmembraneldeformability,lallloflthelfollowinglareltruelexcept:
a. IncreaselinlATPllevel.
b. DecreaselinlATPllevel.
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