GCE
Biology B
H022/01: Foundations of biology
*1327104584*
AS Level
INSTRUCTIONS
• Use black ink. You can use an HB pencil, but only for graphs and diagrams.
• Write your answer to each question in the space provided. If you need extra space use
the lined pages at the end of this booklet. The question numbers must be clearly shown.
• Answer all the questions.
• Where appropriate, your answer should be supported with working. Marks might be
given for using a correct method, even if your answer is wrong.
INFORMATION
• The total mark for this paper is 70.
• The marks for each question are shown in brackets [ ].
• This document has 28 pages.
ADVICE
• Read each question carefully before you start your answer.
© OCR 2025 [601/4721/0] DC (CE/SG) 329633/4
OCR is an exempt Charity
Turn over
Section A
You should spend a maximum of 25 minutes on this section.
Write your answer for each question in the box provided.
1 Which of the statements about peak expiratory flow rate (PEFR) is correct?
A It increases as the age of a person increases.
B It is calculated by multiplying tidal volume by breathing rate.
C It is the maximum rate at which air can be forced out through the mouth.
D It is the volume of air breathed out in the first second of forced exhalation.
, 2
Your answer
[1]
2 Which option about why multicellular plants need transport systems is not correct?
A Assimilates must be transported from source to sink
B Diffusion distances are too long
C Multicellular plants have large surface area to volume ratios
D Water and mineral ions must be transported from roots to leaves
Your answer
[1] 3 The transmission electron micrograph shows the ultrastructure of a mammalian
cell.
P
Which option describes the function of the structure labelled P?
A It produces ATP.
B It stores glycogen.
C It synthesises proteins.
D It synthesises ribosomes.
Your answer
© OCR 2025
, 3
[1] 4 A student observed a blood sample using a light microscope with a calibrated
eyepiece graticule. They measured the diameter of a lymphocyte and calculated its actual
diameter as 12 μm.
One unit of the calibrated eyepiece graticule = 2.4 μm.
What is the diameter of the lymphocyte measured by the student in eyepiece graticule
units?
A 0.2
B 5.0
C 9.6
D 28.8
Your answer
[1]
5 The graph shows the rate of an enzyme-controlled reaction with and without the
addition of a fixed quantity of substance Z.
Without substance Z
Rate of
reaction With substance Z
Substrate concentration
What is the molecule in substance Z?
A Cofactor
B Competitive inhibitor
C Non-competitive inhibitor
D Prosthetic group
Your answer
[1] 6 What would not be included in the emergency treatment given to an adult suffering a
suspected heart attack?
© OCR 2025 Turn over
, 4
A Help them take their usual angina medication.
B Offer them an aspirin tablet to chew, if available.
C Sit them up with their knees bent.
D Use a defibrillator to restore the normal rhythm of the heart.
Your answer
[1]
7 The table shows descriptions of some of the stages and features of apoptosis.
Which of the rows, A to D, is correct ?
Karyorrhexis Pyknosis Role of
phosphatidylserine
A nucleus breaks down nucleus condenses binds to receptors on
lymphocytes
B nucleus breaks down nucleus condenses binds to receptors on
macrophages
C nucleus condenses nucleus breaks down binds to receptors on
lymphocytes
D nucleus condenses nucleus breaks down binds to receptors on
macrophages
Your answer
[1] The karyogram shows chromosomes from a human fetus.
Use the karyogram to answer questions 8 and 9.
© OCR 2025
Biology B
H022/01: Foundations of biology
*1327104584*
AS Level
INSTRUCTIONS
• Use black ink. You can use an HB pencil, but only for graphs and diagrams.
• Write your answer to each question in the space provided. If you need extra space use
the lined pages at the end of this booklet. The question numbers must be clearly shown.
• Answer all the questions.
• Where appropriate, your answer should be supported with working. Marks might be
given for using a correct method, even if your answer is wrong.
INFORMATION
• The total mark for this paper is 70.
• The marks for each question are shown in brackets [ ].
• This document has 28 pages.
ADVICE
• Read each question carefully before you start your answer.
© OCR 2025 [601/4721/0] DC (CE/SG) 329633/4
OCR is an exempt Charity
Turn over
Section A
You should spend a maximum of 25 minutes on this section.
Write your answer for each question in the box provided.
1 Which of the statements about peak expiratory flow rate (PEFR) is correct?
A It increases as the age of a person increases.
B It is calculated by multiplying tidal volume by breathing rate.
C It is the maximum rate at which air can be forced out through the mouth.
D It is the volume of air breathed out in the first second of forced exhalation.
, 2
Your answer
[1]
2 Which option about why multicellular plants need transport systems is not correct?
A Assimilates must be transported from source to sink
B Diffusion distances are too long
C Multicellular plants have large surface area to volume ratios
D Water and mineral ions must be transported from roots to leaves
Your answer
[1] 3 The transmission electron micrograph shows the ultrastructure of a mammalian
cell.
P
Which option describes the function of the structure labelled P?
A It produces ATP.
B It stores glycogen.
C It synthesises proteins.
D It synthesises ribosomes.
Your answer
© OCR 2025
, 3
[1] 4 A student observed a blood sample using a light microscope with a calibrated
eyepiece graticule. They measured the diameter of a lymphocyte and calculated its actual
diameter as 12 μm.
One unit of the calibrated eyepiece graticule = 2.4 μm.
What is the diameter of the lymphocyte measured by the student in eyepiece graticule
units?
A 0.2
B 5.0
C 9.6
D 28.8
Your answer
[1]
5 The graph shows the rate of an enzyme-controlled reaction with and without the
addition of a fixed quantity of substance Z.
Without substance Z
Rate of
reaction With substance Z
Substrate concentration
What is the molecule in substance Z?
A Cofactor
B Competitive inhibitor
C Non-competitive inhibitor
D Prosthetic group
Your answer
[1] 6 What would not be included in the emergency treatment given to an adult suffering a
suspected heart attack?
© OCR 2025 Turn over
, 4
A Help them take their usual angina medication.
B Offer them an aspirin tablet to chew, if available.
C Sit them up with their knees bent.
D Use a defibrillator to restore the normal rhythm of the heart.
Your answer
[1]
7 The table shows descriptions of some of the stages and features of apoptosis.
Which of the rows, A to D, is correct ?
Karyorrhexis Pyknosis Role of
phosphatidylserine
A nucleus breaks down nucleus condenses binds to receptors on
lymphocytes
B nucleus breaks down nucleus condenses binds to receptors on
macrophages
C nucleus condenses nucleus breaks down binds to receptors on
lymphocytes
D nucleus condenses nucleus breaks down binds to receptors on
macrophages
Your answer
[1] The karyogram shows chromosomes from a human fetus.
Use the karyogram to answer questions 8 and 9.
© OCR 2025
