D236 Objective Assessment
Pathophysiology WGU (Updated for
2026/2027 – Verified Questions and
Answers for an A Grade| PDF
Question 1
Turner syndrome
Correct Answer
A chromosomal disorder in females in which either an X chromosome is missing, making
the person XO instead of XX, or part of one X chromosome is deleted.
Question 2
Tay-Sachs Disease
Correct Answer
A human genetic disease caused by a recessive allele for a dysfunctional enzyme leads to the
accumulation of certain lipids in the brain.
Seizures, blindness, and degeneration of motor and mental performance usually become
manifest a few months after birth, followed by death within a few years.
Question 3
Down syndrome
,Correct Answer
A condition of mild to severe intellectual disability and associated physical disorders caused
by an extra copy of chromosome 21
Question 4
Diabetes Insipidus
Correct Answer
Antidiuretic hormone is not secreted adequately, or the kidney is resistant to its effect.
The serum sodium is often elevated due to excess free water losses.
In diabetes insipidus, your blood glucose levels are normal, but your kidneys can't properly
concentrate urine.
Question 5
Cardiac Valve Disease Process
Correct Answer
In heart valve disease, one or more of the valves in your heart doesn't work properly.
Regurgitation (or leakage of the valve). When the valve(s) do not close completely, it causes
blood to flow backward through the valve. This reduces forward blood flow and can lead to
volume overload in the heart.
Stenosis (or narrowing of the valve). When the valve(s) opening becomes narrowed, it limits
the flow of blood out of the ventricles or atria. The heart is forced to pump blood with
increased force to move blood through the narrowed or stiff (stenotic) valve(s).
Question 6
Cardiac Valve Complications
,Correct Answer
Heart valve disease can cause many complications, including:
* Heart failure.
* Stroke.
* Blood clots.
* Heart rhythm abnormalities.
* Death.
Question 7
Respiratory Illness from bats
Correct Answer
Viral hemorrhagic fevers are spread by contact with infected animals or insects. The viruses
that cause viral hemorrhagic fevers live in a variety of animal and insect hosts.
Most commonly, the hosts include mosquitoes, ticks, rodents, or bats. Some viral
hemorrhagic fevers can also be spread from person to person.
Question 8
Anemia
Correct Answer
Different types of anemia include:
Anemia due to vitamin B12 deficiency
Anemia due to folate (folic acid) deficiency
Anemia due to iron deficiency
Anemia of chronic disease
Hemolytic anemia
, Idiopathic aplastic anemia
Megaloblastic anemia
Pernicious anemia
Sickle cell anemia
Thalassemia
Question 9
Acid Base Balance - lung and kidney compensation
Correct Answer
The kidneys have two main ways to maintain acid-base balance - their cells reabsorb
bicarbonate HCO3− from the urine back to the blood and they secrete hydrogen H+ ions
into the urine.
By adjusting the amounts reabsorbed and secreted, they balance the bloodstream's pH.
Question 10
Pyelonephritis
Correct Answer
Inflammation of the renal pelvis and the kidney
Question 11
Prostate cancer
Pathophysiology WGU (Updated for
2026/2027 – Verified Questions and
Answers for an A Grade| PDF
Question 1
Turner syndrome
Correct Answer
A chromosomal disorder in females in which either an X chromosome is missing, making
the person XO instead of XX, or part of one X chromosome is deleted.
Question 2
Tay-Sachs Disease
Correct Answer
A human genetic disease caused by a recessive allele for a dysfunctional enzyme leads to the
accumulation of certain lipids in the brain.
Seizures, blindness, and degeneration of motor and mental performance usually become
manifest a few months after birth, followed by death within a few years.
Question 3
Down syndrome
,Correct Answer
A condition of mild to severe intellectual disability and associated physical disorders caused
by an extra copy of chromosome 21
Question 4
Diabetes Insipidus
Correct Answer
Antidiuretic hormone is not secreted adequately, or the kidney is resistant to its effect.
The serum sodium is often elevated due to excess free water losses.
In diabetes insipidus, your blood glucose levels are normal, but your kidneys can't properly
concentrate urine.
Question 5
Cardiac Valve Disease Process
Correct Answer
In heart valve disease, one or more of the valves in your heart doesn't work properly.
Regurgitation (or leakage of the valve). When the valve(s) do not close completely, it causes
blood to flow backward through the valve. This reduces forward blood flow and can lead to
volume overload in the heart.
Stenosis (or narrowing of the valve). When the valve(s) opening becomes narrowed, it limits
the flow of blood out of the ventricles or atria. The heart is forced to pump blood with
increased force to move blood through the narrowed or stiff (stenotic) valve(s).
Question 6
Cardiac Valve Complications
,Correct Answer
Heart valve disease can cause many complications, including:
* Heart failure.
* Stroke.
* Blood clots.
* Heart rhythm abnormalities.
* Death.
Question 7
Respiratory Illness from bats
Correct Answer
Viral hemorrhagic fevers are spread by contact with infected animals or insects. The viruses
that cause viral hemorrhagic fevers live in a variety of animal and insect hosts.
Most commonly, the hosts include mosquitoes, ticks, rodents, or bats. Some viral
hemorrhagic fevers can also be spread from person to person.
Question 8
Anemia
Correct Answer
Different types of anemia include:
Anemia due to vitamin B12 deficiency
Anemia due to folate (folic acid) deficiency
Anemia due to iron deficiency
Anemia of chronic disease
Hemolytic anemia
, Idiopathic aplastic anemia
Megaloblastic anemia
Pernicious anemia
Sickle cell anemia
Thalassemia
Question 9
Acid Base Balance - lung and kidney compensation
Correct Answer
The kidneys have two main ways to maintain acid-base balance - their cells reabsorb
bicarbonate HCO3− from the urine back to the blood and they secrete hydrogen H+ ions
into the urine.
By adjusting the amounts reabsorbed and secreted, they balance the bloodstream's pH.
Question 10
Pyelonephritis
Correct Answer
Inflammation of the renal pelvis and the kidney
Question 11
Prostate cancer
