g
Genetics and Genomics in Nursing and Health Care
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by Theresa A. Beery, M. Linda Workman
g g g g g g
First Edition
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FULL TEST BANK!!!g g
, Chapterg1:gDNAgStructuregandgFunction
MultiplegChoice
Identifygthegchoicegthatgbestgcompletesgthegstatementgorganswersgthegquestion.
gg A. 1.g Ingwhichgbodygorgcellgareagaregmostggenesginghumansglocated?
A. Nucleus
B. Mitochondrion
C. Cytoplasm
D. Plasmagmembrane
gg A. 2.g Whichgconditiongorgstatementgexemplifiesgthegconceptgofggenomicsgrathergthanggenetics?
A. Theggenegforginsulingisglocatedgongchromosomeg11gingallgpeople.
B. Expressiongofganygsingleggenegisgdependentgonginheritinggtwogalleles.
C. Sex-linkedgrecessivegdisordersgaffectgmalesgmoregoftengthangfemales.
D. Onegallelegforgeachggenegisginheritedgfromgthegmother,gandgonegisginheritedgfromgth
egfather.
gg A. 3.g WhatgisgthegpurposegofgphosphorousgingagDNAgstrand?
A. Linkinggthegnucleotidesgintogagstrand
B. Holdinggcomplementarygstrandsgtogether
C. Ensuringgthatgagpurinegisgalwaysgpairedgwithgagpyrimidine
D. Preventinggthegseparationgofgdouble-strandedgDNAgintogsingle-strandedgDNA
g A.
4.gWhatgisgthegtermgusedgtogdefinegalternativegformsgofgaggenegthatgmaygresultgingdiffere
ntgexpressiongofgthegtraitgcodedgforgbygthatggene?
A. Alleles
B. Bases
C. Centromeres
D. Diploids
g D. 5.gWhatgpercentagegofgbasesgingagstretchgofgdouble-
strandedgDNAgthatgcontainsg30%gguanineg(G)gbasesgwouldgbegadenineg(A)?
A. 70%
B. 60%
C. 30%
D. 20%
g C.
6.gWhatgisgthegtermgusedgtogdescribegthegorganizedgpicturegofgthegpairedgchromosomes
gwithingagcellgusedgtogdeterminegwhethergchromosomegnumbers,gstructures,gandgbandinggpatter
nsgaregnormal?
A. Pedigree
B. Phenotype
C. Karyotype
D. Autotype
g D.
7.gWhatgwouldgbegthegsequencegofgDNAgthatgisgcomplementarygtogagDNAgsectiong
withgthegbasegsequencegofgGGTCAATCCTTAG?
A. GATTCCTAACTGG
B. TTGACCGAAGGCT
C. AACTGGCTTCCGA
D. CCAGTTAGGAATC
,gg B. 8.g Whichgofgthesegcomplementarygbasegpairsgformgthegstrongestgorg“tightest”gassociation?
A. Adeninegandgthymine
B. Cytosinegandgguanine
C. Guaninegandgthymine
D. Cytosinegandgadenine
gg A 9.g WhatgactivitygoccursgduringgMgphasegofgthegcellgcycle?
A. Thegcellgundergoesgcytokinesis.
B. Activitygstops,gandgthegcellg“sleeps.”
C. AllgDNAgisgcompletelygreplicated.
D. Thegcellggreatlygincreasesgproteingsynthesis.
gg B.g g 10.g Whichgchromosomegnumbergrepresentsgthegeuploidgstategforgnormalghumangsomaticgcells?
A. 44
B. 46
C. 47
D. 48
gg A.g 11.g Howgdoesgthegproteomegdiffergfromgtheggenome?
A. Thegproteomegchangesgingresponsegtogintracellulargandgextracellulargsignals.
B. Theggenomegchangesgingresponsegtogintracellulargandgextracellulargsignals.
C. Thegproteomegisgstablegingsomaticgcellsgandgunstableginggermgcells,gwhereasgth
eggenomegisgstablegingbothgsomaticgcellsgandggermgcells.
D. Theggenomegisgstablegingsomaticgcellsgandgunstableginggermgcells,gwhereasgth
egproteomegisgstablegingbothgsomaticgcellsgandggermgcells.
gg C.g g 12.g Whatgisgthegmostgoutstandinggfeaturegofgagmatureghaploidgcell?
A. Itgisgusuallyghomozygous.
B. Thegsexgchromosomesgaregmissing.
C. Onlygonegchromosomegofgeachgpairgisgpresent.
D. DNAgsynthesisgoccursgaftergmitosisginsteadgofgbefore.
gg D.g g 13.g Atgwhatgphasegofgthegcellgcyclegaregchromosomesgvisiblegasgseparategstructures?
A. G1
B. G2
C. S
D. M
gg B.g 14.g WhichgstatementgaboutgthegcellgcyclegphasegofgG0g isgtrue?
A. Hyperplasticggrowthgingplacegofghypertrophicggrowth
B. Performancegofgspecificgdifferentiatedgfunctions
C. Initiationgandgcompletiongofgnucleokinesis
D. ReplicationgofgDNA
gg B.g 15.g WhatgisgthegresultgofgnormalgDNAgreplication?
A. Formationgofgtwognewgdaughtergcells
B. FormationgofgtwogidenticalgsetsgofgDNA
C. Disappearancegofgthegoriginalgparentgcell
D. Activationgandgattachmentgofgspindlegfibers
, gg A.g 16.g Whichgstatementgregardinggchromosomegstructuregorgfunctiongisgtrue?
A. Thegchromatidsgofganygsinglegchromosomegaregknowngasg“sistergchromatids.”
B. Theggenesglocatedgongthegtelomeresgofgchromosomesgaregidenticalgtogtheggenesgi
ngthegcentromeres.
C. Immediatelygbeforegthegmitosisgphasegofgcellgdivision,gthegchromosomesgofgal
lgsomaticgcellsgareghaploid.
D. Agspecificggenegallelegongonegchromosomeghasgagcomplementarygallelegongthegoth
ergchromosomegofgagpair.
gg C.g g 17.g Whygdoesgagpersongwithgnormalgchromosomesgonlyghavegtwogallelesgforganygsingleggenegtrait?
A. Agminimumgofgtwogallelesgisgrequiredgforgthegexpressiongofgmonogenicgtraits.
B. Whengagdominantgallelegisgpairedgwithgagrecessivegallele,gonlygthegdominantgallelegi
sgexpressed,gandgthegrecessivegallelegisgsilent.
C. Onegallelegforgthegmonogenicgtraitgisgongthegpaternallygderivedgchromosome,gan
dgthegothergallelegisgongthegmaternallygderivedgchromosome.
D. Expressiongofgmoregthangtwogallelesgofganygsingle-
genegtraitgresultsgingenhancedgexpressiongofgrecessivegallelesgandgsuppressedge
xpressiongofgdominantgalleles.
gg C 18.g Undergwhatgnormalgconditiongareggenotypegandgphenotypegalwaysgthegsame?
A. Euploidygofgalleles
B. Aneuploidygofgalleles
C. Homozygositygofgalleles
D. Heterozygositygofgalleles
g g D.g 19.g Whatgwouldgbegthegexpectedgresultgofgagdruggthatgaffectedgagparticulargtissuegbygcausinggnewg
DNAgtogformgwithgcovalentgbondsginsteadgofghydrogengbonds?
A. NonegofgthegcellsgingthegaffectedgtissuegwouldgbegablegtogleavegG0g andgentergthegc
ellgcycle.
B. ReplicationgofgDNAgwouldgresultgingidenticalgDNAgstrandsginsteadgo
fgcomplementarygstrands.
C. Mitosisgofgcellsgingthegtissuegwouldgresultgingthegproductiongofgthreegnewgdaught
ergcellsginsteadgofgjustgtwo.
D. Thegnewgcellsgthatgformedgwithingthisgtissuegwouldgnotgbegablegtogcompletegthegne
xtgroundgofgmitosisgsuccessfully.
gg B.g 20.g HowgdoesgthegDNAgenzymegtopoisomerasegcontributegtogDNAgreplication?
A. Unwindsgthegdoubleghelixgandgseparatesgthegdouble-strandedgDNA
B. Createsgag“nick”gingthegDNAgsupercoils,gallowinggthemgtogstraightengbefor
egreplication
C. InitiatesgDNAgsynthesisgingmultiplegsitesgdowngthegstrand,gmakinggthegprocessgmor
egefficient
D. ConnectsgandglinksgthegindividualgpiecesgofgnewlygsynthesizedgDNAgtogformg
agsinglegstrand
gg A.g 21.g WheregisgtelomericgDNAglocated?
A. Atgthegtipsgofgthegpgandgqgarmsgofgchromosomes.
B. Ingthegmitochondriagofgallgsomaticgcells
C. Onlygingtheggermgcellsg(ovagandgsperm)
D. Withingtheghistonesgofgthegsolenoid