PN1005 Pharmacology Midterm questions with answers

PN1005 Pharmacology Midterm |\ |\ |\




questions with answers |\ |\




Pharmacokinetics - CORRECT ANSWERS ✔✔How the body |\ |\ |\ |\ |\ |\ |\



affects the drug |\ |\




4 stages of pharmacokinetics - CORRECT ANSWERS ✔✔1.
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Absorption
2. Distribution
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3. Metabolism
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4. Excretion
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Absorption - CORRECT ANSWERS ✔✔what happens to a
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drug from the time it enters the body until it enters the
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circulating fluid; intravenous administration causes the
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drug to directly enter the circulating blood, bypassing the
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many complications of absorption from other routes.
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Distribution - CORRECT ANSWERS ✔✔The movement of |\ |\ |\ |\ |\ |\ |\



drug to and from the bloodstream and various tissues of
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the body |\

, Pharmacodynamics - CORRECT ANSWERS ✔✔How the |\ |\ |\ |\ |\ |\



drug affects the body |\ |\ |\




Controlled Drugs and Substances Act - CORRECT |\ |\ |\ |\ |\ |\ |\



ANSWERS ✔✔Class 1: heroin |\ |\ |\




Class 2: hydromorphone |\ |\ |\




Class 3: Codeine |\ |\




Biotransformation (metabolism) - CORRECT ANSWERS |\ |\ |\ |\ |\



✔✔the process by which drugs are changed into new, less
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active chemicals
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first pass effect - CORRECT ANSWERS ✔✔a phenomenon
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in which drugs given orally are carried directly to the liver
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after absorption, where they may be largely inactivated
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by liver enzymes before they can enter the general
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circulation; oral drugs frequently are given in higher |\ |\ |\ |\ |\ |\ |\ |\



doses than drugs given by other routes because of this
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early breakdown |\




Protein bound drugs - CORRECT ANSWERS ✔✔Affects the
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distribution of a drug; when the drug is bound to protein, |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\



it is unable to pass through capillary walls; may cause
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drug toxicity. when the patient has a lower-than-expected
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protein level, the distribution of the drug is altered.
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