Which of the following statements about disulfiram [Antabuse] are true? (Select all
that apply.)
Give this one a try later!
, *Disulfiram has no applications outside the treatment of alcoholism.
*Acetaldehyde syndrome may occur from drinking less than an ounce of
alcohol.
*In the absence of alcohol, disulfiram rarely causes significant effects.
*Acetaldehyde syndrome symptoms can last 2 weeks after ingesting
alcohol.
Disulfiram [Antabuse] helps alcoholics avoid drinking by causing
unpleasant effects if alcohol is ingested. Disulfiram has no applications
outside the treatment of alcoholism. This reaction, which may last from 30
minutes to several hours, can be brought on by consuming as little as 7 mL
of alcohol. In the absence of alcohol, disulfiram rarely causes significant
effects. Patients should be made aware that the effects of disulfiram will
persist about 2 weeks after the last dose, and hence continued abstinence
is necessary. Naltrexone [ReVia] reduces the high from drinking alcohol.
Which is a true statement about new drug development? (Select all that apply.)
Give this one a try later!
*Drug trials require that those involved not know which subjects are
receiving the drug or control.
*During preclinical testing, drugs are evaluated for toxicities, kinetic
properties, and useful effects.
Preclinical drug testing is not performed in humans; it is done mostly in
animals. Because drug testing occurs in a relatively small number of
patients, those patients are carefully selected, the drug is taken for a
relatively short time, and not all adverse effects are detected during the
drug testing process. During the testing process, randomized controlled
trials are used, in which the participants are unaware of which subjects are
getting drug, placebo, or control. Kinetics, toxicities, and effectiveness are
tested during the preclinical phase of drug testing.
,A patient is seen daily in a community clinic for the treatment of narcotic addiction.
The nurse would anticipate administration of which medication to support the
patient's recovery efforts?
Give this one a try later!
*Methadone
Methadone is a long-acting oral opioid agonist most often used to help
patients withdraw from opioid dependence. Because opioids are
characterized by cross-dependence, the patient avoids abstinence
symptoms while taking methadone. Later, the patient can be withdrawn
slowly from the methadone, which should be easier, because it is a long-
acting drug.
Why is it important for drugs to have ease of administration?
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*Fewer administration errors
Ease of administration increases convenience and adherence and can
reduce administration errors. Ease of administration is not related to side
effects, chemical stability, or reversibility.
The nurse is teaching a patient about the use of disulfiram [Antabuse]. Which
statement by the patient indicates that the teaching has been effective?
Give this one a try later!
, *"I need to avoid all forms of alcohol, including cough syrups and
aftershave."
Disulfiram [Antabuse] helps alcoholics avoid drinking by causing
unpleasant effects if alcohol is ingested. This reaction, which may last from
30 minutes to several hours, can be brought on by consuming as little as 7
mL of alcohol. Patients must be made aware that consuming any alcohol
while taking disulfiram may produce a severe, potentially fatal, reaction.
Patients must be warned to avoid all forms of alcohol, including alcohol
found in sauces and cough syrups, and alcohol applied to the skin in
aftershave lotions, cologne, and liniments.
The nurse in the emergency department is caring for a patient admitted with cocaine
overdose. Which symptom is most likely associated with this condition?
Give this one a try later!
*Seizure
Overdose is a common problem in cocaine users. Overdose produces
agitation, dizziness, tremor, blurred vision, hyperpyrexia, convulsions,
ventricular dysrhythmias, and hemorrhagic stroke.
When administering a central nervous system depressant, the nurse should closely
observe for drug toxicity in which patient?
Give this one a try later!
*A 3-week-old neonate
The blood-brain barrier is not fully developed at birth. As a result,
that apply.)
Give this one a try later!
, *Disulfiram has no applications outside the treatment of alcoholism.
*Acetaldehyde syndrome may occur from drinking less than an ounce of
alcohol.
*In the absence of alcohol, disulfiram rarely causes significant effects.
*Acetaldehyde syndrome symptoms can last 2 weeks after ingesting
alcohol.
Disulfiram [Antabuse] helps alcoholics avoid drinking by causing
unpleasant effects if alcohol is ingested. Disulfiram has no applications
outside the treatment of alcoholism. This reaction, which may last from 30
minutes to several hours, can be brought on by consuming as little as 7 mL
of alcohol. In the absence of alcohol, disulfiram rarely causes significant
effects. Patients should be made aware that the effects of disulfiram will
persist about 2 weeks after the last dose, and hence continued abstinence
is necessary. Naltrexone [ReVia] reduces the high from drinking alcohol.
Which is a true statement about new drug development? (Select all that apply.)
Give this one a try later!
*Drug trials require that those involved not know which subjects are
receiving the drug or control.
*During preclinical testing, drugs are evaluated for toxicities, kinetic
properties, and useful effects.
Preclinical drug testing is not performed in humans; it is done mostly in
animals. Because drug testing occurs in a relatively small number of
patients, those patients are carefully selected, the drug is taken for a
relatively short time, and not all adverse effects are detected during the
drug testing process. During the testing process, randomized controlled
trials are used, in which the participants are unaware of which subjects are
getting drug, placebo, or control. Kinetics, toxicities, and effectiveness are
tested during the preclinical phase of drug testing.
,A patient is seen daily in a community clinic for the treatment of narcotic addiction.
The nurse would anticipate administration of which medication to support the
patient's recovery efforts?
Give this one a try later!
*Methadone
Methadone is a long-acting oral opioid agonist most often used to help
patients withdraw from opioid dependence. Because opioids are
characterized by cross-dependence, the patient avoids abstinence
symptoms while taking methadone. Later, the patient can be withdrawn
slowly from the methadone, which should be easier, because it is a long-
acting drug.
Why is it important for drugs to have ease of administration?
Give this one a try later!
*Fewer administration errors
Ease of administration increases convenience and adherence and can
reduce administration errors. Ease of administration is not related to side
effects, chemical stability, or reversibility.
The nurse is teaching a patient about the use of disulfiram [Antabuse]. Which
statement by the patient indicates that the teaching has been effective?
Give this one a try later!
, *"I need to avoid all forms of alcohol, including cough syrups and
aftershave."
Disulfiram [Antabuse] helps alcoholics avoid drinking by causing
unpleasant effects if alcohol is ingested. This reaction, which may last from
30 minutes to several hours, can be brought on by consuming as little as 7
mL of alcohol. Patients must be made aware that consuming any alcohol
while taking disulfiram may produce a severe, potentially fatal, reaction.
Patients must be warned to avoid all forms of alcohol, including alcohol
found in sauces and cough syrups, and alcohol applied to the skin in
aftershave lotions, cologne, and liniments.
The nurse in the emergency department is caring for a patient admitted with cocaine
overdose. Which symptom is most likely associated with this condition?
Give this one a try later!
*Seizure
Overdose is a common problem in cocaine users. Overdose produces
agitation, dizziness, tremor, blurred vision, hyperpyrexia, convulsions,
ventricular dysrhythmias, and hemorrhagic stroke.
When administering a central nervous system depressant, the nurse should closely
observe for drug toxicity in which patient?
Give this one a try later!
*A 3-week-old neonate
The blood-brain barrier is not fully developed at birth. As a result,
