ASCP Hematology BUNDLED exams 2023 with 100% correct answers

____________ and ____________ are required for heme synthesis iron and protoporphyrin Fe Transport protein Transferrin Major Fe storage form Ferritin H2O insoluble Fe storage form (long-term) Hemosiderin Excess iron that is stored in tissues and body organs can lead t...

The light-colored zone adjacent to the nucleus in a plasmacyte is the: A. ribosome B. chormatin C. mitochondira D. Golgi area D. Golgi area The majority of the iron in an adult is found as a constituent of: A. hemoglobin B. hemosiderin C. myglobin D. transferrin A. hemoglobin ...

Acanthocytes may be associated with: Severe liver disease. Splenectomy. Malabsorption. Hypothyroidism. Vitamin E deficiency. Abetalipoproteinemia. Schistocytes may be associated with: Hemolytic uremic syndrome. Thrombotic thrombocytopenia purpura. Disseminated intravascular coagulati...

The light-colored zone adjacent to the nucleus in a plasmacyte is the: A. ribosome B. chromatin C. mitochondria D. Golgi area D. Golgi area The majority of the iron in an adult is found as a constituent of: A. hemoglobin B. hemosiderin C. myoglobin D. transferrin A. hemoglobin ...

Dohle bodies Light blue patches in cytoplasm of neutrophils. Infection, burns Erythrocytes O2 transport. Produced in BM Mean Corpuscular Hemoglobin (MCH) formula (HGBx10)/RBC Mean Corpuscular Hemoglobin Concentration (MCHC) formulao (HGBx100)/HCT Granulocytes Defense...

The majority of the iron in an adult is found as a constituent of hemoglobin In order for hemoglobin to combine reversibly with oxygen, the iron must In the ferrous state Which description best fits the Donath-Landsteiner antibody IgG biphasic hemolysin Spherocytes are a defi...

Insufficient centrifugation will result in: A. A false increase in hematocrit (Hct) value B. A false decrease in Hct value C. No effect on Hct value D. All of these options, depending on the patient A. Insufficient centrifugation does not pack down the red blood cells; therefore, the Hct, wh...

Bone marrow and Peripheral blood Growth factors that stimulate cell line maturation are: Locations of active marrow in adults Flat bones What conditions are associated with increased storage of iron Hemosiderosis Hemochromatosis Transferrin iron transport protein Iro...

Order of heme synthesis Porphobilinogen, Uroporphyrinogen, Coproporphyrinogen, Protoporphyrinogen Macrocytic The characteristic erythrocyte found in pernicious anemia Idiopathic Hemochromatosis Results in iron overload in tissues Phlebotomy treatment Causes iron deficiency d...

hexose monohosphate shunt found in the erythrocyte to provide reduced glutathione to prevent oxidation of hemoglobin May-hegglin anomaly Dohle bodies and giant platelets. Autosomal dominant disorder Chediak-Higashi syndrome associated w/ cytoplasmic granule fusion Shift to th...

CMP Common Myeloid Progenitor -Granulocyte -Erythrocyte -Monocyte -Megakaryocyte CLP Common Lymphoid Progenitor -T-lymphocyte -B-lymphocyte -NK cell Pronormoblast 14-24 um N:C ratio 8:1 1-3 nucleoli Fine chromatin Basophilic Normoblast 12-17 um N:C ratio 6:1 No n...

Right shift Decreased oxygen affinity/increased O2 release high 2,3-DPG, increased body temperature, decreased pH Left shift Increased oxygen affinity low 2,3-DPG levels, decreased body temp, increased pH Howell-Jolly bodies DNA, remnants of nuceli/nuclear fragments, aggregates of...

Paroxysmal Cold Hemoglobinuria (PCH) Stem cell mutation in the PIGA gene that causes abnormal differentiated hematopoietic cells to be cloned. These cells bind large amounts of complement, causing hemolysis. Spurr Cell Anemia Acquired hemolytic anemia due to liver disease in which serum lip...