Latest Update 2026/2027 (Verified Answers) | GRADED
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A 48-year-old man with a known history of asthma takes daily theophylline. He is
found unconscious in his bathroom with an open bottle of theophylline that
is now empty nearby. He is found by EMS to be apneic and pulseless. What is the
most likely cause of death in this patient?
(A) Apnea
(B) Cardiac arrhythmia
(C) Pulmonary embolism
(D) Seizures
(E) Tetany
(B) Cardiac arrhythmia
A 23-year-old man is a driver who is involved in a motor vehicle accident. He is
brought to the emergency department for evaluation. He is found to have a
blood alcohol level of 850 mg/dL. Because of the way the body handles ethanol,
the conventional "halflife" to describe its metabolism does not apply. Which of
the following drugs at therapeutic concentrations exhibits the same property?
(A) Ibuprofen
(B) Phenytoin
(C) Simvastatin
(D) Tolbutamide (E) Valproic acid
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,(B) Phenytoin
An 18-year-old woman presents to her primary
care physician after experiencing a one-sided
headache for the fourth time in the last 2 years.
Her headaches have all been similar in nature.
She says the pain is worst right behind her eye
and that she feels nauseous and cannot stand
bright lights or loud noises while she is having a
headache. The physician prescribes sumatriptan.
What is the mechanism of action of this
medication?
(A) Blocking cyclooxygenase enzymes in the CNS
(B) Blocking serotonin-mediated nociceptive signaling (C) Blocking
synthesis of proinflammatory prostaglandins around nerve
endings
(D) Stimulating m-receptors in the brain
(E) Stimulating k-receptors in the brain
(B) Blocking serotonin-mediated nociceptive signaling
Recent studies into the pathogenesis of halothane induced malignant
hyperthermia indicate which of the following as the likely implicating cause?
(A) Drug toxicity
(B) Excitation-contraction coupling defect
(C) Myoplasmic sodium defect
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,(D) Oxygen-hemoglobin concentration deficit
(E) Neural overmodulation
(B) Excitation-contraction coupling defect
Thiopental is used as an anesthetic agent during surgery to repair a small-bowel
obstruction in a 78-year-old man. Approximately 1 day after his surgery,
toxicology studies still reveal some thiopental present in the bloodstream. What is
the most likely explanation for this finding?
(A) Hepatitis
(B) Hepatic insufficiency
(C) Physiologic metabolism
(D) Renal failure
(E) Trauma to bowel vasculature
(C) Physiologic metabolism
A 17-year-old man is brought to the emergency department with severe right
lower quadrant pain that he first felt around his umbilicus. His white blood cell
count is 12,000/mL of blood. He is taken to the operating
room for emergent laparoscopic appendectomy. About an hour into the surgery,
his body temperature
spikes and CO2 production rises uncontrollably. What is the next step in the
treatment of this patient?
(A) Acetaminophen
(B) Bromocriptine
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, (C) Dantrolene
(D) Diazepam
(E) Naproxen
(C) Dantrolene
A 39-year-old man who suffered a work-related injury has chronic back pain. A
morphine pain pump was implanted to control his chronic pain. Formerly, he had
chronic diarrhea which is now much improved. What is the most likely
explanation for this finding?
(A) Improved gastrointestinal motility
(B) Improved intestinal circular muscle tone
(C) Weakened anal sphincter tone
(D) Weakened rectal balloon dilation pressure
(E) Weakened transverse colonic musculature
(B) Improved intestinal circular muscle tone
A 6-year-old boy presents to the emergency department with an altered mental
status. He is hyperventilating, has a rash on his hands, and a high fever. His
mother has been giving him an antipyretic for his fever for the past 2 days. The
patient's liver enzymes are elevated. His mental status continues to decline. What
is the mechanism of action of the most likely medication given to this child by his
mother?
(A) Inhibits phospholipase A2
(B) Irreversibly inhibits cyclooxygenases 1 and 2
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