NUR 328 Exam 3 Questions with Correct Answers
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Terms in this set (233)
basic diuretics MOAs block Na+ and Cl- reabsorption, increase urine output
three basic renal filtration, reabsorption, active tubular secretion
processes
99% of water, nutrients, and electrolytes, and any laid
What can be reabsorbed
soluble drugs are reabsorbed back in to the blood
in the nephron?
stream .
Where does tubular The proximal convoluted tubule
secretion occur?
What is actively secreted Organic acid and bases, drugs are secreted from
in the PCT? blood to urine
PCT(65%), ascending LofH(20%), and DCT(10% early,
Sites of Action of Diuretics
5-1% in distal)
Loop, Thiazides, K+ sparing, Osmotic, Carbonic
Classifications of Diuretics
Anhydrase inhibitors
Loop Diuretics furosemide, bumetanide, torsemide, ethacrynic acid
Saying for Loop Diuretics Furry Bums Tour Ecstasy
Block Na+/Cl- reabsorption in the ascending LofH,
Furosemide (Lasix) MOA
which causes increased H20 excretion(urine)
Therapeutic Use of Pulmonary , hepatic, cardiac, and renal edema, HTN,
Furosemide low renal blood flow/GFR(kidney failure)
, Hypo(Na, Cl, K, Mg, Ca+), hyperglycemia,
Adverse effects of
hyperuricemia, hypotension, ototoxicity(high doses
Furosemide
and is reversible), lipid change low HDL.
What must you monitor Blood pressure, urine output, and weight
with Furosemide?
Drug interactions of Digoxin, ototoxic drugs, K+ sparring, lithium,
Furosemide antihypertensive drugs, NSAIDSf
Hydrochlorothiazide, Chlorothiazide,
Thiazides methyclothiazide, chlorthalidone, Indapamide,
metolazone
Saying for Thiazide Drugs HideYour, Methy, 2Children, Inda, Me
Blocks NA/Cl reabsorption in the early
MOA of thiazides
DCT(10%=lower diuresis than Loop Diuretics)
Are thiazides effective No, they can't be used for patients with kidney
with GFR? damage
TU of Thiazides and Essential HTN(predisposed, or overweight) AND
related diuretics edema
HYPO(Na, CL, K, Mg, ), HypoVOLemia,
Adverse Effects of
HYPER:glycemia, uricemia, and calcemia
Thiazides
Increases Bad Cholesterol and TG
Drug Interactions of Digoxin, antihypertensive drugs, lithium toxicity,
Thiazides NSAIDS, CAN be used with Ototoxic drugs
Potassium Sparing Drugs: Spironolactone
Aldosterone Antagonist
Potassium Sparing Drugs: Triamterene, Amiloride
Non-Aldosterone
Antagonist
How to remember K+ SPARING and SPIRO
Sparing Alodsterone
Antagonist
Save
Terms in this set (233)
basic diuretics MOAs block Na+ and Cl- reabsorption, increase urine output
three basic renal filtration, reabsorption, active tubular secretion
processes
99% of water, nutrients, and electrolytes, and any laid
What can be reabsorbed
soluble drugs are reabsorbed back in to the blood
in the nephron?
stream .
Where does tubular The proximal convoluted tubule
secretion occur?
What is actively secreted Organic acid and bases, drugs are secreted from
in the PCT? blood to urine
PCT(65%), ascending LofH(20%), and DCT(10% early,
Sites of Action of Diuretics
5-1% in distal)
Loop, Thiazides, K+ sparing, Osmotic, Carbonic
Classifications of Diuretics
Anhydrase inhibitors
Loop Diuretics furosemide, bumetanide, torsemide, ethacrynic acid
Saying for Loop Diuretics Furry Bums Tour Ecstasy
Block Na+/Cl- reabsorption in the ascending LofH,
Furosemide (Lasix) MOA
which causes increased H20 excretion(urine)
Therapeutic Use of Pulmonary , hepatic, cardiac, and renal edema, HTN,
Furosemide low renal blood flow/GFR(kidney failure)
, Hypo(Na, Cl, K, Mg, Ca+), hyperglycemia,
Adverse effects of
hyperuricemia, hypotension, ototoxicity(high doses
Furosemide
and is reversible), lipid change low HDL.
What must you monitor Blood pressure, urine output, and weight
with Furosemide?
Drug interactions of Digoxin, ototoxic drugs, K+ sparring, lithium,
Furosemide antihypertensive drugs, NSAIDSf
Hydrochlorothiazide, Chlorothiazide,
Thiazides methyclothiazide, chlorthalidone, Indapamide,
metolazone
Saying for Thiazide Drugs HideYour, Methy, 2Children, Inda, Me
Blocks NA/Cl reabsorption in the early
MOA of thiazides
DCT(10%=lower diuresis than Loop Diuretics)
Are thiazides effective No, they can't be used for patients with kidney
with GFR? damage
TU of Thiazides and Essential HTN(predisposed, or overweight) AND
related diuretics edema
HYPO(Na, CL, K, Mg, ), HypoVOLemia,
Adverse Effects of
HYPER:glycemia, uricemia, and calcemia
Thiazides
Increases Bad Cholesterol and TG
Drug Interactions of Digoxin, antihypertensive drugs, lithium toxicity,
Thiazides NSAIDS, CAN be used with Ototoxic drugs
Potassium Sparing Drugs: Spironolactone
Aldosterone Antagonist
Potassium Sparing Drugs: Triamterene, Amiloride
Non-Aldosterone
Antagonist
How to remember K+ SPARING and SPIRO
Sparing Alodsterone
Antagonist
