All Correct Answers 2025-2026
Updated.
What metabolic events occur in the Cori cycle?
A)Lactate produced in the liver is converted to glucose in the muscle.
B)Lactate produced in the active muscle is converted to glucose in the liver.
C)Lactate can exit the muscle into the bloodstream and then enters the liver to be converted to
galactose
via galactoneogenesis.
D)Glucose is converted to pyruvate via the glycolysis pathway in the skeletal muscle and that
pyruvate
exits the muscle into the bloodstream and then enters the liver to be oxidized to acetyl-CoA via
the pyruvate dehydrogenase pathway. - Answer B
Which enzyme below can be used in both glycolysis and gluconeogenesis?
A.Triose phosphate isomerase
B.Phosphofructokinase
C.Pyruvatecarboxylase
D.Hexokinase
E. Phosphoenolpyruvatecarboxykinase - Answer A
Which reactions below occur in the mitochondria? Select all that apply.
A.oxaloacetate+NADH→malate+NAD+
B.oxaloacetate+GTP→phosphoenolpyruvate+GDP+CO2
C.glucose-6-phosphate+H2O→glucose+Pi
D.pyruvate + CO2 + ATP + H2O → oxaloacetate + ADP + Pi + 2 H+
E.fructose-1,6-bisphosphate + H2O → fructose-6-phosphate + Pi
F. lactate + NAD+ → pyruvate + NADH - Answer A and D
Which enzyme would be directly impacted when you have a deficiency of vitamin B7?
A.Glycerolkinase
, E.
Phosphoenolpyruvatecarboxykinase - Answer C
Energy is consumed in 3 reactions of the gluconeogenic pathway. What are the enzymes for two
of those reactions? (Directly taken from Dr. Dre's practice exam 5)
A.Malate dehydrogenase and phosphoenol pyruvate carboxykinase(PEPCK)
B.Fructose-1,6-bis phosphatase and pyruvate carboxylase
C.Pyruvate carboxylase and phosphoenolpyruvate carboxykinase (PEPCK)
D.Fructose-1,6-bis phosphatase and phosphoenol pyruvate carboxykinase (PEPCK)
E.Pyruvate carboxylase and glucose-6-phosphatase - Answer C
Which of the following reactions in gluconeogenesis involves the consumption of ATP? (Not all
reactants/products for each reaction are shown.)
A.Fructose 1,6-bisphosphate → Fructose 6-phosphate
B.3-Phosphoglycerate→1,3-Bisphosphoglycerate
C.Glucose6-phosphate→Glucose
D.Oxaloacetate→Phosphoenolpyruvate
E. A and D - Answer B
The pathway of gluconeogenesis contains three hydrolysis reactions. Which reaction below is
NOT one of those three hydrolysis reactions? (Not all reactants/products for each reaction are
shown.)
A. Dihydroxyacetone phosphate + glyceraldehyde 3-phosphate → Fructose 1,6-bisphosphate
.BGlucose6-phosphate→Glucose
C. Phosphoenolpyruvate→2-Phosphoglycerate
D. Fructose 1,6-bisphosphate → Fructose 6-phosphate - Answer A
How many ATPs are required to synthesize 12 molecules of glucose in the liver? (For the
purpose of this question, assume that all the glucose molecules came from the reduction of
pyruvates and glycerol doesn'tcontribute to the DHAPs in the gluconeogenic pathway.)
A. 36
B. 72