Gottesman & Shields (1966) → Twin study
G -large sample (teenagers → 60’s)
50/50 mix men and women
-may not be representative twins unusual
Most admitted hospital 40’s 50’s after experience WW11
Trauma → schizophrenia
R -deliberately replicating small-scale studies (reliable)
-by modern not reliable // no DNA tests
Assigned by physical resemble and fingerprints
-Diagnosed using DSM-1
Classification schizophrenia changed 4x since
A -people know they have a genetic preposition
Know to avoid triggers (excessive alcohol)
V -Vague ‘psychotic disorders relating to schizophrenia
Subjective
E -parents heavily involved in the process if young
-mentally ill, full consent?
-high benefits
, Kety et al. (1968) → Adoption study
G -large sample (teenagers → women in ’40s)
Taken from the Danish adoption register
R -Replicated study ‘75 ‘78 ‘94 got similar (test-retest)
-inter-rater 4 psychologists diagnosed (only 4 cases psych not agree)
-diagnostic categories vague/unscientific/subjective
A -If families are aware of a genetic
Diathesis-stress model suggests predisposition requires a trigger
V -concurrent validity (from prev. Studies, Gott)
-construct validity (from theory diathe)
E -pp not approached / only data used
Under Danish law no consent needed
-if Kety manipulated results could cause distress to the public
of schizophrenia is genetically heritable.
G -large sample (teenagers → 60’s)
50/50 mix men and women
-may not be representative twins unusual
Most admitted hospital 40’s 50’s after experience WW11
Trauma → schizophrenia
R -deliberately replicating small-scale studies (reliable)
-by modern not reliable // no DNA tests
Assigned by physical resemble and fingerprints
-Diagnosed using DSM-1
Classification schizophrenia changed 4x since
A -people know they have a genetic preposition
Know to avoid triggers (excessive alcohol)
V -Vague ‘psychotic disorders relating to schizophrenia
Subjective
E -parents heavily involved in the process if young
-mentally ill, full consent?
-high benefits
, Kety et al. (1968) → Adoption study
G -large sample (teenagers → women in ’40s)
Taken from the Danish adoption register
R -Replicated study ‘75 ‘78 ‘94 got similar (test-retest)
-inter-rater 4 psychologists diagnosed (only 4 cases psych not agree)
-diagnostic categories vague/unscientific/subjective
A -If families are aware of a genetic
Diathesis-stress model suggests predisposition requires a trigger
V -concurrent validity (from prev. Studies, Gott)
-construct validity (from theory diathe)
E -pp not approached / only data used
Under Danish law no consent needed
-if Kety manipulated results could cause distress to the public
of schizophrenia is genetically heritable.
