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ADVANCED PATHOPHYSIOLOGY- UTMB 5355 EXAM -1 EXAM WITH CORRECT ANSWERS

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ADVANCED PATHOPHYSIOLOGY- UTMB 5355 EXAM -1 EXAM WITH CORRECT ANSWERS

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ADVANCED PATHOPHYSIOLOGY- UTMB ||\\||\\ ||\\||\\ ||\\||\\




5355 EXAM #1 EXAM WITH CORRECT ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\




ANSWERS

Transcription - correct answer✔✔synthesis of RNA from DNA ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\




Transcription results in - correct answer✔✔mRNA ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\




RNA polymerase makes - correct answer✔✔mRNA
||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\




mRNA - correct answer✔✔makes proteins
||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\




RNA polymerase - correct answer✔✔binds to DNA
||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\




Transcription factors (TFs) - correct answer✔✔A regulatory protein that binds ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\




to DNA and affects transcription of specific genes. Can wither activate or repress
||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\




expression of genes
||\\||\\ ||\\||\\ ||\\||\\




Termination of transcription - correct answer✔✔RNA polymerase reaches a ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\




terminator sequence (Stop codon) and detaches from the template ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\




Translation - correct answer✔✔Process by which mRNA is decoded and a ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\




protein is produced. Protein assembly ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\




Translation takes place in the - correct answer✔✔cytoplasm ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\

,Codon - correct answer✔✔A specific sequence of three bases on a strand of
||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\




DNA or RNA that provides genetic code information for a amino acid
||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\




Amino acids are - correct answer✔✔building blocks of proteins
||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\




tRNA - correct answer✔✔An RNA molecule that functions as an interpreter
||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\




between nucleic acid and protein language by picking up specific amino acids
||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\




and recognizing the appropriate codons in the mRNA
||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\




Codons allow - correct answer✔✔for DNA and RNA to communicate
||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\




Gene Regulation - correct answer✔✔the process of turning genes on and off
||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\




Gene Regulation occurs - correct answer✔✔during transcription
||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\




Transcription factors (TFs) determine - correct answer✔✔amount of protein ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\




product made ||\\||\\




Nucleotide - correct answer✔✔DNA subunit; 1 DNA, 1 phosphate, 1 ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\




nitrogenous base ||\\||\\




Mutation - correct answer✔✔permanent change in a DNA /RNA sequence that ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\




affects genetic information ||\\||\\ ||\\||\\




germline mutation - correct answer✔✔happens in germ cells, inheritable, in all
||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\




cells

,somatic mutation - correct answer✔✔A mutation that occurs in the body cells
||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\




from spontaneous development. Cannot be inherited. Acquired
||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\




causes of mutations - correct answer✔✔• Incorrect copying of the DNA
||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\




sequence/
Environmental
•Exposure ||\\||\\




•Spontaneous


silent mutation - correct answer✔✔alters a base but does not change the
||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\




amino acid ||\\||\\




DNA is - correct answer✔✔master blueprint for human being
||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\




Gene - correct answer✔✔the basic unit of inheritance
||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\




DNA makes - correct answer✔✔proteins
||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\




Chromosomes - correct answer✔✔threadlike structures made of DNA ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\




molecules that contain the genes ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\




23 pairs of - correct answer✔✔chromosomes
||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\




Allele - correct answer✔✔variant of a gene
||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\




A cell holds how many alleles of each gene? - correct answer✔✔2, one from
||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\




mom and one from dad ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\

, Phenotype - correct answer✔✔An organism's physical appearance, or visible ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\




traits. Affected by environment ||\\||\\ ||\\||\\ ||\\||\\




Genotype - correct answer✔✔genetic makeup of an organism ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\




locus - correct answer✔✔Location of a gene on a chromosome
||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\




Homozygous - correct answer✔✔An organism that has two identical alleles for ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\




a trait ||\\||\\




Heterozygous - correct answer✔✔An organism that has two different alleles for ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\




a trait
||\\||\\ ||\\||\\




Recessive - correct answer✔✔trait of an organism that can be masked by the ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\




dominant form of a trait ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\




Dominant - correct answer✔✔An allele that is always expressed ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\




Carrier - correct answer✔✔A person whose genotype includes a gene with
||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\




disease that is not expressed in the phenotype. ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\




Expresstivity - correct answer✔✔the degree to which a particular genotype is ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\




expressed in the phenotype ||\\||\\ ||\\||\\ ||\\||\\




Spontaneous mutations are - correct answer✔✔mutation that occurs within the ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\




body cells and NOT the germline cells, caused by errors in DNA
||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\ ||\\||\\

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