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NR 507 MIDTERM EXAM QUESTIONS & VERIFIED CORRECT ANSWERS RATED 100% COMPLETE

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November 14, 2025
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Written in
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NR 507 MIDTERM EXAM QUESTIONS
& VERIFIED CORRECT ANSWERS
RATED 100% COMPLETE

Hypersensitivity: Type 1 - correct answer ✔✔-Mediated IgE

-inflammation due to mast cell degranultion

-anaphylactic, asthma, hay fever

treatment: epinephrine



Hypersensitivity: Type 2 - correct answer ✔✔-Cytotoxic reaction: tissue specific

-binds to the antigen ON THE CELL SURFACE

-macrophages are primary effectors cells involved

cause tissue damage or alter function



Hypersensitivity 2 - correct answer ✔✔-Graves Disease (hyperthyroidism) -alters function not
destroy

-blood transfusions reaction- transfused erythrocytes are destroyed by agglutination or lysis

-drug allergies

-hemolytic anemia



Hypersensitivity: type 3 - correct answer ✔✔-Not organ specific

-antibody binds to soluble antigen OUTSIDE THE CELL SURFACE that was released into the blood
or bodily fluids, and the complex is then deposited in the tissues



Hypersensitivity: Type 3 - correct answer ✔✔-rheumatoid arthritis

,-Systemic Lupus Erythematosus (SLE)

-Raynaud's



Hives (urticaria) - correct answer ✔✔Hypersensitivity Type 1



First responders to innate the immune system - correct answer ✔✔Neutrophils



Allergic contact dermatitis - correct answer ✔✔Hypersensitivity Type IV



Type 2 cytotoxic hypersensitivity mediated by: - correct answer ✔✔-IgG IgM

-macrophages are primary effort cells

-



Serum Sickness - correct answer ✔✔type 3 hypersensitivity



Hypersensitivity IV, - correct answer ✔✔-is more of a delayed immune response.

-mediated T-cells attack tissue directly (no antibodies)



Autoimmune - correct answer ✔✔-diseases in which the body makes antibodies directed
against its own tissues

-



Primary immunodeficiency - correct answer ✔✔-Genetic; inherited

-result of single gene defects

-B and T cell deficiencies

, secondary immunodeficiency - correct answer ✔✔-acquired



Common cause of secondary immunodeficiency - correct answer ✔✔Malnutrition



Most patients diagnosed with SLE will have a positive ? - correct answer ✔✔antinuclear
antibody (ANA)



SLE (lupus) - correct answer ✔✔-Facial rash

-vasculitis

- tissue inflammation



Renal disease associated with autoimmunity? - correct answer ✔✔Glomerulonephritis



Sjogren's syndrome - correct answer ✔✔Inflammation in salivary and lacrimal glands



SLE - correct answer ✔✔Autoantibodies and auto-active t-cells against DNA and nucleoprotein



Sjögren's syndrome immune changes: - correct answer ✔✔Autoantibodies and auto-reactive t-
cells against apoptotic cells



rheumatoid arthritis manifestations: - correct answer ✔✔Joint inflammation, stiffness, pain,
loss of range of motion



Rheumatoid Arthritis immune changes: - correct answer ✔✔T-cells and B cells against joint
associated antigens



MS manifestations - correct answer ✔✔Formation of sclerotic plaque in the brain, leads to
Muscle weakness and ataxia
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