MY NR 565 WEEK 4 STUDY GUIDE
QUESTIONS & CORRECT ANSWERS
pharm treatment for osteoarthritis.
NSAIDS – inhibit COX1 (aspirin, ibuprofen)
COX2-(celexicob)
non pharm treatment for osteoarthritis
heat, yoga, accupuncture
· Complications of untreated gout
Can cause erosion and irreversible joint damage, renal damage, tophi
treatment of acute gout flare w colchicine
Low dose colchicine for acute gout.
Colchicine: 1.2 mg intitally, followed by 0.6 mg after 1 hr, maximum 1.8mg total dose
colchicine adverse effects
diarrhea, nausea, vomiting, cramps, abd, pain, fatigue, HA, pharyngolaryngeal pain
, colchicine and statin
should be avoided - muscle injury/rhabdo
colchicine pt education
low sperm count, avoid in pregnancy, avoid grapefruit, increased side effects > 65yo, don't take
with statin
long term tx of gout
allopurinol
allopurinol can cause
rash, Stephen Jhonson's syndrome
allopurinol drug interactions
aspirin, warfarin antibiotics, ACEI
NSAIDS/colchicine
should be administered with febuxostat
QUESTIONS & CORRECT ANSWERS
pharm treatment for osteoarthritis.
NSAIDS – inhibit COX1 (aspirin, ibuprofen)
COX2-(celexicob)
non pharm treatment for osteoarthritis
heat, yoga, accupuncture
· Complications of untreated gout
Can cause erosion and irreversible joint damage, renal damage, tophi
treatment of acute gout flare w colchicine
Low dose colchicine for acute gout.
Colchicine: 1.2 mg intitally, followed by 0.6 mg after 1 hr, maximum 1.8mg total dose
colchicine adverse effects
diarrhea, nausea, vomiting, cramps, abd, pain, fatigue, HA, pharyngolaryngeal pain
, colchicine and statin
should be avoided - muscle injury/rhabdo
colchicine pt education
low sperm count, avoid in pregnancy, avoid grapefruit, increased side effects > 65yo, don't take
with statin
long term tx of gout
allopurinol
allopurinol can cause
rash, Stephen Jhonson's syndrome
allopurinol drug interactions
aspirin, warfarin antibiotics, ACEI
NSAIDS/colchicine
should be administered with febuxostat
