2025/2026 Exam Questions with 100%
Correct Answers | Latest Update
How does hypoalbuminemia affect the process of prescribing? - 🧠
ANSWER ✔✔Low albumin = more free drug (bc the drug can't bind to
albumin aka protein) = increased adverse effects
What is a Black Box Warning: - 🧠 ANSWER ✔✔is considered a
contraindication to administer that drug.
What is the drugs half-life? - 🧠 ANSWER ✔✔Half-life specifically means the
amount of time it takes for an administered drug to be halfway cleared from
the system.
Peak of action: - 🧠 ANSWER ✔✔the time between drug administration and
maximum concentration of drug in the blood stream. Best therapeutic
effect.
,Duration of action: - 🧠 ANSWER ✔✔the time between onset of action and
metabolism of drug below the minimum needed for an effect. The length of
time you have the drug in your system.
According to the WHO what is the first step in the prescribing process? - 🧠
ANSWER ✔✔The first step is to define the patient's problem
The second step is to - 🧠 ANSWER ✔✔specify the therapeutic objective
The third step is to - 🧠 ANSWER ✔✔choose which drug or treatment is
needed.
Step 4 of the WHO approach: - 🧠 ANSWER ✔✔Start the treatment
Step 5 of the WHO approach: - 🧠 ANSWER ✔✔Educate the patient
Step 6 of the WHO approach: - 🧠 ANSWER ✔✔Monitor the treatment
Phase 1 of drug development: - 🧠 ANSWER ✔✔The drug is tested on
healthy volunteers
Phase 2 of drug development: - 🧠 ANSWER ✔✔trials with people who have
the disease for which the drug is thought to be effective
,Phase 3 of drug development: - 🧠 ANSWER ✔✔Large numbers of patients
in medical research centers receive the drug in phase 3. This larger
sampling provides information about infrequent or rare adverse effects. The
FFA will approve a new drug application if phase 3 studies are satisfactory.
Phase 4 of drug development: - 🧠 ANSWER ✔✔This phase is voluntary
and involves postmarket surveillance of the drug's therapeutic effects at the
completion of phase 3. The pharmaceutical company receives reports from
doctors and other health care professionals about the therapeutic results
and adverse effects of the drug. Some medications, for example, have
been found to be toxic and have been removed from the market after their
initial release.
Explain first pass metabolism - 🧠 ANSWER ✔✔much of the drug is lost in
the absorption process. The liver metabolizes many drugs, thus reduces
the bioavailabilty of the drug.
What is the fasted route of absorption: - 🧠 ANSWER ✔✔The fastest route
of absorption is inhalation, and not as mistakenly considered the IV
administration.
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, Why does the GI tract take longer to absorb? - 🧠 ANSWER ✔✔The GI tract
is lined with epithelial cells; drugs must permeate through these cells in
order to be absorbed into the circulatory system.
What is One particular cellular barrier that may prevent absorption of a
given drug? - 🧠 ANSWER ✔✔the cell membrane. Cell membranes are
essentially lipid bilayers which form a semipermeable membrane. Pure lipid
bilayers are generally permeable only to small and uncharged solutes,
hence whether or not a molecule is ionized will affect its absorption, since
ionic molecules are charged.
What is solubility? - 🧠 ANSWER ✔✔Solubility favors charged species,
permeability favors neutral species. Some molecules have special
exchange proteins and channels to facilitate movement from the lumen into
the circulation.
Why does absorption occur at a slower rate for oral, IM, SQ routes? - 🧠
ANSWER ✔✔Absorption occurs at a slower rate because the complex
membrane systems of GI mucosal layers, muscle, and skin delay drug
passage.